Ksenia Blinova
Ksenia Blinova
Verified email at fda.hhs.gov
TitleCited byYear
Distribution of mitochondrial NADH fluorescence lifetimes: steady-state kinetics of matrix NADH interactions
K Blinova, S Carroll, S Bose, AV Smirnov, JJ Harvey, JR Knutson, ...
Biochemistry 44 (7), 2585-2594, 2005
1362005
Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias
K Blinova, J Stohlman, J Vicente, D Chan, L Johannesen, ...
Toxicological Sciences 155 (1), 234-247, 2016
892016
Late sodium current block for drug‐induced long QT syndrome: results from a prospective clinical trial
L Johannesen, J Vicente, JW Mason, C Erato, C Sanabria, K Waite‐Labott, ...
Clinical Pharmacology & Therapeutics 99 (2), 214-223, 2016
802016
Mitochondrial NADH fluorescence is enhanced by complex I binding
K Blinova, RL Levine, ES Boja, GL Griffiths, ZD Shi, B Ruddy, RS Balaban
Biochemistry 47 (36), 9636-9645, 2008
712008
Use of 32P To Study Dynamics of the Mitochondrial Phosphoproteome
AM Aponte, D Phillips, RK Hopper, DT Johnson, RA Harris, K Blinova, ...
Journal of proteome research 8 (6), 2679-2695, 2009
452009
International multisite study of human-induced pluripotent stem cell-derived cardiomyocytes for drug proarrhythmic potential assessment
K Blinova, Q Dang, D Millard, G Smith, J Pierson, L Guo, M Brock, HR Lu, ...
Cell reports 24 (13), 3582-3592, 2018
442018
Common genetic variant risk score is associated with drug-induced QT prolongation and torsade de pointes risk: a pilot study
DG Strauss, J Vicente, L Johannesen, K Blinova, JW Mason, P Weeke, ...
Circulation 135 (14), 1300-1310, 2017
422017
Use of human MonoMac6 cells for development of in vitro assay predictive of adjuvant safety in vivo
M Zaitseva, T Romantseva, K Blinova, J Beren, L Sirota, D Drane, ...
Vaccine 30 (32), 4859-4865, 2012
422012
32P labeling of protein phosphorylation and metabolite association in the mitochondria matrix
AM Aponte, D Phillips, RA Harris, K Blinova, S French, DT Johnson, ...
Methods in enzymology 457, 63-80, 2009
352009
Fluctuation analysis of mitochondrial NADH fluorescence signals in confocal and two‐photon microscopy images of living cardiac myocytes
K Blinova, C Combs, P Kellman, RS Balaban
Journal of microscopy 213 (1), 70-75, 2004
252004
Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1β and TRIF/IRF3
Y Endo, K Blinova, T Romantseva, H Golding, M Zaitseva
PloS one 9 (5), e98517, 2014
232014
Clinical trials in a dish
DG Strauss, K Blinova
Trends in pharmacological sciences 38 (1), 4-7, 2017
172017
Comprehensive in vitro proarrhythmia assay (CiPA) update from a cardiac safety research consortium/health and environmental sciences institute/FDA Meeting
DG Strauss, G Gintant, Z Li, W Wu, K Blinova, J Vicente, JR Turner, ...
Therapeutic innovation & regulatory science 53 (4), 519-525, 2019
132019
Comparative analysis of media effects on human induced pluripotent stem cell-derived cardiomyocytes in proarrhythmia risk assessment
D Schocken, J Stohlman, J Vicente, D Chan, D Patel, MK Matta, V Patel, ...
Journal of pharmacological and toxicological methods 90, 39-47, 2018
122018
Laser-induced saturation of fluorescence for complex organic molecules
VI Yuzhakov, KG Yevsyukhina, SV Patsayeva
ALT'97 International Conference on Laser Surface Processing 3404, 388-396, 1998
91998
Acute effects of nonexcitatory electrical stimulation during systole in isolated cardiac myocytes and perfused heart
K Blinova, J Stohlman, V Krauthamer, A Knapton, E Bloomquist, RA Gray
Physiological reports 2 (8), e12106, 2014
22014
Assessment of proarrhythmic potential of drugs in optogenetically paced induced pluripotent stem cell-derived cardiomyocytes
D Patel, J Stohlman, Q Dang, DG Strauss, K Blinova
Toxicological Sciences 170 (1), 167-179, 2019
12019
Steady state kinetic properties of NADH binding and utilization in the mitochondrial matrix. A NADH fluorescence lifetime study.
K Blinova, S Carroll, SK Bose, AV Smirnov, JJ Harvey, JR Knutson, ...
Biophysical Journal 86 (1), 469A-469A, 2004
12004
Clinical Trial in a Dish: Personalized Stem Cell–Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT‐Prolonging Drugs
K Blinova, D Schocken, D Patel, C Daluwatte, J Vicente, JC Wu, ...
Clinical and translational science, 2019
2019
Evaluating the use of microelectrode array technology and cell-based neuronal culture models for proconvulsant risk assessment: progress from the HESI NeuTox consortium
DC Millard, AM Nicolini, CA Arrowood, HB Hayes, JA Bradley, CJ Strock, ...
Journal of Pharmacological and Toxicological Methods 99, 106595, 2018
2018
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