Marcel Kool

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Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center Heidelberg (KiTZ)Verified email at kitz-heidelberg.de
Paul A. NorthcottSt. Jude Children's Research HospitalVerified email at stjude.org
Michael TaylorTorontoVerified email at sickkids.ca
David T. W. JonesHead of Division - 'Pediatric Glioma Research', DKFZVerified email at dkfz.de
Torsten PietschProfessor and Chairman, Institute of Neuropathology, University of BonnVerified email at uni-bonn.de
Yoon-Jae ChoProfessor of PediatricsVerified email at ohsu.edu
K PajtlerVerified email at dkfz.de
Scott L. PomeroyBronson Crothers Professor of Neurology, Harvard Medical SchoolVerified email at childrens.harvard.edu
Just VlakProfessor of Virology, Wageningen UniversityVerified email at wur.nl
Lukas ChavezAssistant Professor, Department of Medicine, University of California, San Diego (UCSD)Verified email at ucsd.edu
Frank BaasLUMCVerified email at lumc.nl
Vijay RamaswamyHospital for Sick Children, University of TorontoVerified email at sickkids.ca
Jan KosterGroupleader Bioinformatics, AUMC, location AMCVerified email at amsterdamumc.nl
James M. OlsonSeattle Children's Research InstituteVerified email at seattlechildrens.org
Jens BuntSenior Researcher at Princess Máxima Center for Pediatric OncologyVerified email at prinsesmaximacentrum.nl
Steve CliffordDirector, Newcastle University Centre for CancerVerified email at ncl.ac.uk
Nada JabadoMcGill Univ.Verified email at mcgill.ca
Jan Molenaar-Verified email at prinsesmaximacentrum.nl
Alexander EGGERMONTPrincess Maxima Center & University Medical Center Utrecht, Netherlands alexander.eggermontVerified email at prinsesmaximacentrum.nl
Leendert LooijengaProfessor Translational Patho-OncologyVerified email at prinsesmaximacentrum.nl

Marcel Kool

PI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology Utrecht

Verified email at dkfz.de

Pediatric Neurooncology cancer genomics brain tumors medulloblastoma ependymoma


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013	8985	2013
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012	2415	2012
A family of drug transporters: the multidrug resistance-associated proteins P Borst, R Evers, M Kool, J Wijnholds Journal of the National Cancer Institute 92 (16), 1295-1302, 2000	2259	2000
Molecular subgroups of medulloblastoma: the current consensus MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ... Acta neuropathologica 123, 465-472, 2012	1863	2012
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012	1799	2012
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018	1788	2018
Analysis of Expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, Homologues of the Multidrug Resistance-associated Protein Gene (MRP1), in Human … M Kool, M de Haas, GL Scheffer, RJ Scheper, MJT van Eijk, JA Juijn, ... Cancer research 57 (16), 3537-3547, 1997	1153	1997
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1146	2020
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123, 473-484, 2012	1055	2012
The landscape of genomic alterations across childhood cancers SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ... Nature 555 (7696), 321-327, 2018	1040	2018
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015	945	2015
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012	898	2012
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ... Acta neuropathologica 124, 439-447, 2012	878	2012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012	876	2012
The multidrug resistance protein family P Borst, R Evers, M Kool, J Wijnholds Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999	861	1999
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1-2), 59-71, 2012	853	2012
The whole-genome landscape of medulloblastoma subtypes PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ... Nature 547 (7663), 311-317, 2017	803	2017
MRP3, an organic anion transporter able to transport anti-cancer drugs M Kool, M Van Der Linden, M de Haas, GL Scheffer, JML De Vree, ... Proceedings of the National Academy of Sciences 96 (12), 6914-6919, 1999	796	1999
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ... PloS one 3 (8), e3088, 2008	786	2008
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ... Journal of clinical oncology 29 (11), 1424, 2011	770	2011

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