D‐Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis J Sasabe, T Chiba, M Yamada, K Okamoto, I Nishimoto, M Matsuoka, ... The EMBO journal 26 (18), 4149-4159, 2007 | 311 | 2007 |
Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons T Chiba, M Yamada, J Sasabe, K Terashita, M Shimoda, M Matsuoka, ... Molecular psychiatry 14 (2), 206-222, 2009 | 230 | 2009 |
D-amino acid oxidase controls motoneuron degeneration through D-serine J Sasabe, Y Miyoshi, M Suzuki, M Mita, R Konno, M Matsuoka, K Hamase, ... Proceedings of the National Academy of Sciences 109 (2), 627-632, 2012 | 222 | 2012 |
Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota J Sasabe, Y Miyoshi, S Rakoff-Nahoum, T Zhang, M Mita, BM Davis, ... Nature microbiology 1 (10), 1-7, 2016 | 179 | 2016 |
Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin … T Chiba, M Yamada, Y Hashimoto, M Sato, J Sasabe, Y Kita, K Terashita, ... Journal of Neuroscience 25 (44), 10252-10261, 2005 | 118 | 2005 |
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant … K Kanekura, Y Hashimoto, Y Kita, J Sasabe, S Aiso, I Nishimoto, ... Journal of biological chemistry 280 (6), 4532-4543, 2005 | 116 | 2005 |
Deciphering the landscape of host barriers to Listeria monocytogenes infection T Zhang, S Abel, P Abel zur Wiesch, J Sasabe, BM Davis, DE Higgins, ... Proceedings of the National Academy of Sciences 114 (24), 6334-6339, 2017 | 81 | 2017 |
Implanted cannula-mediated repetitive administration of Aβ25–35 into the mouse cerebral ventricle effectively impairs spatial working memory M Yamada, T Chiba, J Sasabe, M Nawa, H Tajima, T Niikura, K Terashita, ... Behavioural brain research 164 (2), 139-146, 2005 | 80 | 2005 |
Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer's disease M Yamada, T Chiba, J Sasabe, K Terashita, S Aiso, M Matsuoka Neuropsychopharmacology 33 (8), 2020-2032, 2008 | 77 | 2008 |
Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers J Sasabe, M Suzuki, Y Miyoshi, Y Tojo, C Okamura, S Ito, R Konno, ... PloS one 9 (1), e86504, 2014 | 70 | 2014 |
Emerging role of d-amino acid metabolism in the innate defense J Sasabe, M Suzuki Frontiers in microbiology 9, 371372, 2018 | 68 | 2018 |
Chemoproteomic profiling of host and pathogen enzymes active in cholera SK Hatzios, S Abel, J Martell, T Hubbard, J Sasabe, D Munera, L Clark, ... Nature chemical biology 12 (4), 268-274, 2016 | 60 | 2016 |
Chemoproteomic profiling of host and pathogen enzymes active in cholera SK Hatzios, S Abel, J Martell, T Hubbard, J Sasabe, D Munera, L Clark, ... Nature chemical biology 12 (4), 268-274, 2016 | 60 | 2016 |
High-resolution genetic analysis of the requirements for horizontal transmission of the ESBL plasmid from Escherichia coli O104:H4 Y Yamaichi, MC Chao, J Sasabe, L Clark, BM Davis, N Yamamoto, H Mori, ... Nucleic acids research 43 (1), 348-360, 2015 | 59 | 2015 |
Activity of D-amino acid oxidase is widespread in the human central nervous system J Sasabe, M Suzuki, N Imanishi, S Aiso Frontiers in synaptic neuroscience 6, 14, 2014 | 56 | 2014 |
Glycolytic flux controls D-serine synthesis through glyceraldehyde-3-phosphate dehydrogenase in astrocytes M Suzuki, J Sasabe, Y Miyoshi, K Kuwasako, Y Muto, K Hamase, ... Proceedings of the National Academy of Sciences 112 (17), E2217-E2224, 2015 | 53 | 2015 |
Alteration of intrinsic amounts of d-serine in the mice lacking serine racemase and d-amino acid oxidase Y Miyoshi, R Konno, J Sasabe, K Ueno, Y Tojo, M Mita, S Aiso, K Hamase Amino acids 43, 1919-1931, 2012 | 50 | 2012 |
Distinctive roles of d-amino acids in the homochiral world: chirality of amino acids modulates mammalian physiology and pathology J Sasabe, M Suzuki The Keio journal of medicine 68 (1), 1-16, 2018 | 47 | 2018 |
Colivelin prolongs survival of an ALS model mouse T Chiba, M Yamada, J Sasabe, K Terashita, S Aiso, M Matsuoka, ... Biochemical and biophysical research communications 343 (3), 793-798, 2006 | 47 | 2006 |
Host-microbe cross-talk governs amino acid chirality to regulate survival and differentiation of B cells M Suzuki, T Sujino, S Chiba, Y Harada, M Goto, R Takahashi, M Mita, ... Science Advances 7 (10), eabd6480, 2021 | 38 | 2021 |