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Dr. Renata Kasprzyk
Dr. Renata Kasprzyk
University of Konstanz
Verified email at fuw.edu.pl
Title
Cited by
Cited by
Year
Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies
MR Baranowski, A Nowicka, AM Rydzik, M Warminski, R Kasprzyk, ...
The Journal of organic chemistry 80 (8), 3982-3997, 2015
392015
2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to …
K Drazkowska, R Tomecki, M Warminski, N Baran, D Cysewski, A Depaix, ...
Nucleic acids research 50 (16), 9051-9071, 2022
292022
Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase
R Kasprzyk, TJ Spiewla, M Smietanski, S Golojuch, L Vangeel, ...
Antiviral Research 193, 105142, 2021
262021
Structural insights into the interaction of clinically relevant phosphorothioate mRNA cap analogs with translation initiation factor 4E reveal stabilization via electrostatic …
M Warminski, J Kowalska, E Nowak, D Kubacka, R Tibble, R Kasprzyk, ...
ACS Chemical Biology 16 (2), 334-343, 2021
202021
7-Methylguanosine monophosphate analogues with 5′-(1, 2, 3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase
M Kozarski, D Kubacka, BA Wojtczak, R Kasprzyk, MR Baranowski, ...
Bioorganic & Medicinal Chemistry 26 (1), 191-199, 2018
172018
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
M Zmudzinski, W Rut, K Olech, J Granda, M Giurg, M Burda-Grabowska, ...
Scientific reports 13 (1), 9161, 2023
122023
Enzymatic assays to explore viral mRNA capping machinery
R Kasprzyk, J Jemielity
ChemBioChem 22 (23), 3236-3253, 2021
122021
Acetylpyrene-labelled 7-methylguanine nucleotides: unusual fluorescence properties and application to decapping scavenger activity monitoring
R Kasprzyk, J Kowalska, Z Wieczorek, M Szabelski, R Stolarski, ...
Organic & Biomolecular Chemistry 14 (16), 3863-3868, 2016
122016
Fluorescent Turn‐On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap‐Recognizing Proteins
R Kasprzyk, BJ Starek, S Ciechanowicz, D Kubacka, J Kowalska, ...
Chemistry–A European Journal 25 (27), 6728-6740, 2019
102019
Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators
S Walczak, PJ Sikorski, R Kasprzyk, J Kowalska, J Jemielity
Organic & Biomolecular Chemistry 16 (36), 6741-6748, 2018
102018
Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications
N Kleczewska, PJ Sikorski, Z Warminska, L Markiewicz, R Kasprzyk, ...
Chemical Science 12 (30), 10242-10251, 2021
72021
N1-Propargylguanosine Modified mRNA Cap Analogs: Synthesis, reactivity, and applications to the study of cap-binding proteins
M Kopcial, BA Wojtczak, R Kasprzyk, J Kowalska, J Jemielity
Molecules 24 (10), 1899, 2019
72019
Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy
A Wojtczak, R Kasprzyk, M Warmiński, K Ubych, D Kubacka, PJ Sikorski, ...
Scientific Reports 11 (1), 7687, 2021
62021
Direct High‐Throughput Screening Assay for mRNA Cap Guanine‐N7 Methyltransferase Activity
R Kasprzyk, M Fido, A Mamot, P Wanat, M Smietanski, M Kopcial, ...
Chemistry–A European Journal 26 (49), 11266-11275, 2020
62020
ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions
P Wanat, R Kasprzyk, M Kopcial, PJ Sikorski, D Strzelecka, J Jemielity, ...
Chemical communications 54 (70), 9773-9776, 2018
62018
Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation
S Golojuch, M Kopcial, D Strzelecka, R Kasprzyk, N Baran, PJ Sikorski, ...
Bioorganic & Medicinal Chemistry 28 (13), 115523, 2020
52020
Fluorescence anisotropy assay with guanine nucleotides provides access to functional analysis of Gαi1 proteins
A Pepanian, P Sommerfeld, R Kasprzyk, T Kühl, FA Binbay, C Hauser, ...
Analytical Chemistry 94 (41), 14410-14418, 2022
22022
Fluorescence-based activity screening assay reveals small molecule inhibitors of vaccinia virus mRNA decapping enzyme D9
M Bednarczyk, JK Peters, R Kasprzyk, J Starek, M Warminski, T Spiewla, ...
ACS Chemical Biology 17 (6), 1460-1471, 2022
22022
A desthiobiotin labelled NAD+ analogue to uncover Poly (ADP‐ribose) polymerase 1 protein targets
S Rieth, D Spliesgar, J Orth, M Lehner, R Kasprzyk, F Stengel, A Marx
ChemBioChem, e202300797, 2024
2024
Metody badania białek związanych z metabolizmem końca 5'mRNA oparte na nukleotydowych sondach molekularnych
R Kasprzyk
2021
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