Nicole Sampson
Nicole Sampson
University Professor of Chemistry, University of Rochester
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A Thiolase of Mycobacterium tuberculosis Is Required for Virulence and Production of Androstenedione and Androstadienedione from Cholesterol
NM Nesbitt, X Yang, P Fontán, I Kolesnikova, I Smith, NS Sampson, ...
Infection and immunity 78 (1), 275-282, 2010
Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration
K Zarrabi, A Dufour, J Li, C Kuscu, A Pulkoski-Gross, J Zhi, Y Hu, ...
Journal of Biological Chemistry 286 (38), 33167-33177, 2011
Role of the hemopexin domain of matrix metalloproteinases in cell migration
A Dufour, NS Sampson, S Zucker, J Cao
Journal of cellular physiology 217 (3), 643-651, 2008
Pathogen roid rage: Cholesterol utilization by Mycobacterium tuberculosis
MF Wipperman, NS Sampson, ST Thomas
Critical reviews in biochemistry and molecular biology 49 (4), 269-293, 2014
Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox …
PI Lario, N Sampson, A Vrielink
Journal of molecular biology 326 (5), 1635-1650, 2003
Crystal Structure Determination of Cholesterol Oxidase from Streptomyces and Structural Characterization of Key Active Site Mutants,
QK Yue, IJ Kass, NS Sampson, A Vrielink
Biochemistry 38 (14), 4277-4286, 1999
Mediation of sperm-egg fusion: evidence that mouse egg α6β1 integrin is the receptor for sperm fertilinβ
H Chen, NS Sampson
Chemistry & biology 6 (1), 1-10, 1999
Segmental motion in catalysis: investigation of a hydrogen bond critical for loop closure in the reaction of triosephosphate isomerase
NS Sampson, JR Knowles
Biochemistry 31 (36), 8488-8494, 1992
Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides
A Dufour, S Zucker, NS Sampson, C Kuscu, J Cao
Journal of Biological Chemistry 285 (46), 35944-35956, 2010
Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9
A Dufour, NS Sampson, J Li, C Kuscu, RC Rizzo, JL DeLeon, J Zhi, ...
Cancer research 71 (14), 4977-4988, 2011
Rv1106c from Mycobacterium tuberculosis Is a 3β-Hydroxysteroid Dehydrogenase
X Yang, E Dubnau, I Smith, NS Sampson
Biochemistry 46 (31), 9058-9067, 2007
Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase
NS Sampson, JR Knowles
Biochemistry 31 (36), 8482-8487, 1992
Cholesterol Metabolism Increases the Metabolic Pool of Propionate in Mycobacterium tuberculosis
X Yang, NM Nesbitt, E Dubnau, I Smith, NS Sampson
Biochemistry 48 (18), 3819-3821, 2009
Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism
ST Thomas, BC VanderVen, DR Sherman, DG Russell, NS Sampson
Journal of Biological Chemistry 286 (51), 43668-43678, 2011
Synthesis of copolymers by alternating ROMP (AROMP)
A Song, KA Parker, NS Sampson
Journal of the American Chemical Society 131 (10), 3444-3445, 2009
Antibacterial studies of cationic polymers with alternating, random, and uniform backbones
A Song, SG Walker, KA Parker, NS Sampson
ACS chemical biology 6 (6), 590-599, 2011
Hit generation in TB drug discovery: from genome to granuloma
T Yuan, NS Sampson
Chemical reviews 118 (4), 1887-1916, 2018
Dynamic requirements for a functional protein hinge
JG Kempf, J Jung, C Ragain, NS Sampson, JP Loria
Journal of Molecular Biology 368 (1), 131-149, 2007
Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease
N Ueki, S Lee, NS Sampson, MJ Hayman
Nature communications 4 (1), 2735, 2013
Cholesterol oxidase: physiological functions
J Kreit, NS Sampson
The FEBS journal 276 (23), 6844-6856, 2009
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