| CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence CL Stallings, NC Stephanou, L Chu, A Hochschild, BE Nickels, ... Cell 138 (1), 146-159, 2009 | 258 | 2009 |
| Structural basis for bacterial transcription-coupled DNA repair AM Deaconescu, AL Chambers, AJ Smith, BE Nickels, A Hochschild, ... Cell 124 (3), 507-520, 2006 | 241 | 2006 |
| 5′ end nicotinamide adenine dinucleotide cap in human cells promotes RNA decay through DXO-mediated deNADding X Jiao, SK Doamekpor, JG Bird, BE Nickels, L Tong, RP Hart, M Kiledjian Cell 168 (6), 1015-1027. e10, 2017 | 216 | 2017 |
| A role for interaction of the RNA polymerase flap domain with the σ subunit in promoter recognition K Kuznedelov, L Minakhin, A Niedziela-Majka, SL Dove, D Rogulja, ... Science 295 (5556), 855-857, 2002 | 202 | 2002 |
| The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA JG Bird, Y Zhang, Y Tian, N Panova, I Barvík, L Greene, M Liu, B Buckley, ... Nature 535 (7612), 444-447, 2016 | 201 | 2016 |
| Interactions between RNA polymerase and the “core recognition element” counteract pausing IO Vvedenskaya, H Vahedian-Movahed, JG Bird, JG Knoblauch, ... Science 344 (6189), 1285-1289, 2014 | 181 | 2014 |
| Direct detection of abortive RNA transcripts in vivo SR Goldman, RH Ebright, BE Nickels Science 324 (5929), 927-928, 2009 | 160 | 2009 |
| NanoRNAs prime transcription initiation in vivo SR Goldman, JS Sharp, IO Vvedenskaya, J Livny, SL Dove, BE Nickels Molecular cell 42 (6), 817-825, 2011 | 127 | 2011 |
| An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3 JM Schifano, IO Vvedenskaya, JG Knoblauch, M Ouyang, BE Nickels, ... Nature communications 5 (1), 3538, 2014 | 112 | 2014 |
| Structure of a ternary transcription activation complex D Jain, BE Nickels, L Sun, A Hochschild, SA Darst Molecular cell 13 (1), 45-53, 2004 | 109 | 2004 |
| Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17 JC Milne, RS Roy, AC Eliot, NL Kelleher, A Wokhlu, B Nickels, CT Walsh Biochemistry 38 (15), 4768-4781, 1999 | 108 | 1999 |
| The interaction between σ70 and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation BE Nickels, SJ Garrity, V Mekler, L Minakhin, K Severinov, RH Ebright, ... Proceedings of the National Academy of Sciences 102 (12), 4488-4493, 2005 | 104 | 2005 |
| Protein–protein and protein–DNA interactions of σ70 region 4 involved in transcription activation by λcI BE Nickels, SL Dove, KS Murakami, SA Darst, A Hochschild Journal of molecular biology 324 (1), 17-34, 2002 | 104 | 2002 |
| The σ70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter BE Nickels, J Mukhopadhyay, SJ Garrity, RH Ebright, A Hochschild Nature structural & molecular biology 11 (6), 544-550, 2004 | 103 | 2004 |
| tRNA is a new target for cleavage by a MazF toxin JM Schifano, JW Cruz, IO Vvedenskaya, R Edifor, M Ouyang, RN Husson, ... Nucleic acids research 44 (3), 1256-1270, 2016 | 101 | 2016 |
| Growth-regulating Mycobacterium tuberculosis VapC-mt4 toxin is an isoacceptor-specific tRNase JW Cruz, JD Sharp, ED Hoffer, T Maehigashi, IO Vvedenskaya, ... Nature communications 6 (1), 7480, 2015 | 88 | 2015 |
| Regulation of RNA polymerase through the secondary channel BE Nickels, A Hochschild Cell 118 (3), 281-284, 2004 | 86 | 2004 |
| Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction LF Westblade, EA Campbell, C Pukhrambam, JC Padovan, BE Nickels, ... Nucleic acids research 38 (22), 8357-8369, 2010 | 81 | 2010 |
| Massively systematic transcript end readout,“MASTER”: transcription start site selection, transcriptional slippage, and transcript yields IO Vvedenskaya, Y Zhang, SR Goldman, A Valenti, V Visone, DM Taylor, ... Molecular cell 60 (6), 953-965, 2015 | 75 | 2015 |
| The σ70 subunit of RNA polymerase is contacted by the λQ antiterminator during early elongation BE Nickels, CW Roberts, H Sun, JW Roberts, A Hochschild Molecular cell 10 (3), 611-622, 2002 | 75 | 2002 |
