| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 8 (4), 445-544, 2012 | 11713* | 2012 |
| International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ... The Lancet 391 (10135), 2128-2139, 2018 | 1423 | 2018 |
| Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ... The Journal of pathology 232 (2), 199-209, 2014 | 1308 | 2014 |
| Hypoxia signalling through mTOR and the unfolded protein response in cancer BG Wouters, M Koritzinsky Nature Reviews Cancer 8 (11), 851-864, 2008 | 999 | 2008 |
| Apoptosis, p53, and tumor cell sensitivity to anticancer agents JM Brown, BG Wouters Cancer research 59 (7), 1391-1399, 1999 | 976 | 1999 |
| ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ... The EMBO journal 24 (19), 3470-3481, 2005 | 852 | 2005 |
| Cancer classification using the Immunoscore: a worldwide task force J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ... Journal of translational medicine 10, 1-10, 2012 | 851 | 2012 |
| The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5 KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ... The Journal of clinical investigation 120 (1), 127-141, 2010 | 808 | 2010 |
| Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ... Molecular and cellular biology 22 (21), 7405-7416, 2002 | 803 | 2002 |
| Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ... Molecular and cellular biology 21 (10), 3436-3444, 2001 | 728 | 2001 |
| Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and-Independent Mechanisms and Contributes to Drug Resistance JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ... Molecular and Cellular Biology 24 (7), 2875-2889, 2004 | 499 | 2004 |
| Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis JC Sluimer, JM Gasc, JL van Wanroij, N Kisters, M Groeneweg, ... Journal of the American College of Cardiology 51 (13), 1258-1265, 2008 | 490 | 2008 |
| Activating transcription factor 4 is translationally regulated by hypoxic stress JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ... Molecular and cellular biology 24 (17), 7469-7482, 2004 | 480 | 2004 |
| Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer D De Ruysscher, M Pijls-Johannesma, SM Bentzen, A Minken, ... J Clin Oncol 24 (7), 1057-1063, 2006 | 399 | 2006 |
| Cells at intermediate oxygen levels can be more important than the" hypoxic fraction" in determining tumor response to fractionated radiotherapy BG Wouters, JM Brown Radiation research 147 (5), 541-550, 1997 | 397 | 1997 |
| Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ... The EMBO journal 25 (5), 1114-1125, 2006 | 388 | 2006 |
| Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ... Cancer research 68 (2), 605-614, 2008 | 329 | 2008 |
| The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ... Nature 510 (7504), 268-272, 2014 | 319 | 2014 |
| Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ... Clinical cancer research 19 (24), 6741-6750, 2013 | 285 | 2013 |
| Low-Dose Hyper-radiosensitivity: A Consequence of Ineffective Cell Cycle Arrest of Radiation-Damaged G2-Phase Cells B Marples, BG Wouters, SJ Collis, AJ Chalmers, MC Joiner Radiation research 161 (3), 247-255, 2004 | 280 | 2004 |
Philippe LambinProfessor of Precision Medicine, Maastricht UniversityVerified email at maastrichtuniversity.nl
