Bradly Wouters
Bradly Wouters
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Verified email at
Cited by
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
F Pagès, B Mlecnik, F Marliot, G Bindea, FS Ou, C Bifulco, A Lugli, ...
The Lancet 391 (10135), 2128-2139, 2018
Towards the introduction of the ‘Immunoscore’in the classification of malignant tumours
J Galon, B Mlecnik, G Bindea, HK Angell, A Berger, C Lagorce, A Lugli, ...
The Journal of pathology 232 (2), 199-209, 2014
Hypoxia signalling through mTOR and the unfolded protein response in cancer
BG Wouters, M Koritzinsky
Nature Reviews Cancer 8 (11), 851-864, 2008
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
JM Brown, BG Wouters
Cancer research 59 (7), 1391-1399, 1999
Cancer classification using the Immunoscore: a worldwide task force
J Galon, F Pagès, FM Marincola, HK Angell, M Thurin, A Lugli, I Zlobec, ...
Journal of translational medicine 10, 1-10, 2012
ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ...
The EMBO journal 24 (19), 3470-3481, 2005
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
KMA Rouschop, T van den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
C Koumenis, C Naczki, M Koritzinsky, S Rastani, A Diehl, N Sonenberg, ...
Molecular and cellular biology 22 (21), 7405-7416, 2002
Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells
TN Seagroves, HE Ryan, H Lu, BG Wouters, M Knapp, P Thibault, ...
Molecular and cellular biology 21 (10), 3436-3444, 2001
Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and-Independent Mechanisms and Contributes to Drug Resistance
JT Erler, CJ Cawthorne, KJ Williams, M Koritzinsky, BG Wouters, C Wilson, ...
Molecular and Cellular Biology 24 (7), 2875-2889, 2004
Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis
JC Sluimer, JM Gasc, JL van Wanroij, N Kisters, M Groeneweg, ...
Journal of the American College of Cardiology 51 (13), 1258-1265, 2008
Activating transcription factor 4 is translationally regulated by hypoxic stress
JD Blais, V Filipenko, M Bi, HP Harding, D Ron, C Koumenis, BG Wouters, ...
Molecular and cellular biology 24 (17), 7469-7482, 2004
Cells at intermediate oxygen levels can be more important than the" hypoxic fraction" in determining tumor response to fractionated radiotherapy
BG Wouters, JM Brown
Radiation research 147 (5), 541-550, 1997
Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer
D De Ruysscher, M Pijls-Johannesma, SM Bentzen, A Minken, ...
J Clin Oncol 24 (7), 1057-1063, 2006
Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
M Koritzinsky, MG Magagnin, T van den Beucken, R Seigneuric, ...
The EMBO journal 25 (5), 1114-1125, 2006
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance
N Chan, M Koritzinsky, H Zhao, R Bindra, PM Glazer, S Powell, ...
Cancer research 68 (2), 605-614, 2008
Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response
VE Zannella, A Dal Pra, H Muaddi, TD McKee, S Stapleton, J Sykes, ...
Clinical cancer research 19 (24), 6741-6750, 2013
Low-Dose Hyper-radiosensitivity: A Consequence of Ineffective Cell Cycle Arrest of Radiation-Damaged G2-Phase Cells
B Marples, BG Wouters, SJ Collis, AJ Chalmers, MC Joiner
Radiation research 161 (3), 247-255, 2004
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