David E. Kaplan, MD MSc FACP FAASLD
David E. Kaplan, MD MSc FACP FAASLD
University of Pennsylvania Perelman School of Medicine
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Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization
N Nakamoto, DE Kaplan, J Coleclough, Y Li, ME Valiga, M Kaminski, ...
Gastroenterology 134 (7), 1927-1937. e2, 2008
Increased risk for hepatocellular carcinoma persists up to 10 years after HCV eradication in patients with baseline cirrhosis or high FIB-4 scores
GN Ioannou, LA Beste, PK Green, AG Singal, EB Tapper, AK Waljee, ...
Gastroenterology 157 (5), 1264-1278. e4, 2019
Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 T-cell responses in acute hepatitis C
DE Kaplan, K Sugimoto, K Newton, ME Valiga, F Ikeda, A Aytaman, ...
Gastroenterology 132 (2), 654-666, 2007
Risk factors and incidence of gastric cancer after detection of Helicobacter pylori infection: a large cohort study
S Kumar, DC Metz, S Ellenberg, DE Kaplan, DS Goldberg
Gastroenterology 158 (3), 527-536. e7, 2020
Association of provider specialty and multidisciplinary care with hepatocellular carcinoma treatment and mortality
M Serper, TH Taddei, R Mehta, K D’Addeo, F Dai, A Aytaman, ...
Gastroenterology 152 (8), 1954-1964, 2017
Incidence and mortality of acute‐on‐chronic liver failure using two definitions in patients with compensated cirrhosis
N Mahmud, DE Kaplan, TH Taddei, DS Goldberg
Hepatology 69 (5), 2150-2163, 2019
Association of distance from a transplant center with access to waitlist placement, receipt of liver transplantation, and survival among US veterans
DS Goldberg, B French, KA Forde, PW Groeneveld, T Bittermann, ...
Jama 311 (12), 1234-1243, 2014
Delta hepatitis within the Veterans Affairs medical system in the United States: Prevalence, risk factors, and outcomes
T Kushner, M Serper, DE Kaplan
Journal of hepatology 63 (3), 586-592, 2015
Dysfunctional B‐cell activation in cirrhosis resulting from hepatitis C infection associated with disappearance of CD27‐Positive B‐cell population
H Doi, TK Iyer, E Carpenter, H Li, KM Chang, RH Vonderheide, ...
Hepatology 55 (3), 709-719, 2012
Identifying barriers to hepatocellular carcinoma surveillance in a national sample of patients with cirrhosis
DS Goldberg, TH Taddei, M Serper, R Mehta, E Dieperink, A Aytaman, ...
Hepatology 65 (3), 864-874, 2017
Development and performance of an algorithm to estimate the Child-Turcotte-Pugh score from a national electronic healthcare database
DE Kaplan, F Dai, A Aytaman, M Baytarian, R Fox, K Hunt, A Knott, ...
Clinical Gastroenterology and Hepatology 13 (13), 2333-2341. e6, 2015
A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease
CA Emdin, ME Haas, AV Khera, K Aragam, M Chaffin, D Klarin, G Hindy, ...
PLoS genetics 16 (4), e1008629, 2020
Effects of hypercholesterolemia and statin exposure on survival in a large national cohort of patients with cirrhosis
DE Kaplan, MA Serper, R Mehta, R Fox, B John, A Aytaman, M Baytarian, ...
Gastroenterology 156 (6), 1693-1706. e12, 2019
Relationship between adherence to hepatitis C virus therapy and virologic outcomes: a cohort study
V Lo Re III, V Teal, AR Localio, VK Amorosa, DE Kaplan, R Gross
Annals of internal medicine 155 (6), 353-360, 2011
Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis
DE Kaplan, F Ikeda, Y Li, N Nakamoto, S Ganesan, ME Valiga, FA Nunes, ...
Journal of hepatology 48 (6), 903-913, 2008
Background progenitor activation is associated with recurrence after hepatectomy of combined hepatocellular‐cholangiocarcinoma
X Cai, J Zhai, DE Kaplan, Y Zhang, L Zhou, X Chen, G Qian, Q Zhao, Y Li, ...
Hepatology 56 (5), 1804-1816, 2012
Starting dose of sorafenib for the treatment of hepatocellular carcinoma: a retrospective, multi-institutional study
KA Reiss, S Yu, R Mamtani, R Mehta, K D’Addeo, EP Wileyto, TH Taddei, ...
Journal of Clinical Oncology 35 (31), 3575, 2017
Hepatitis C viraemia reversibly maintains subset of antigen‐specific T‐bet+ tissue‐like memory B cells
LY Chang, Y Li, DE Kaplan
Journal of viral hepatitis 24 (5), 389-396, 2017
Declining cirrhosis hospitalizations in the wake of the COVID-19 pandemic: a national cohort study
N Mahmud, RA Hubbard, DE Kaplan, M Serper
Gastroenterology 159 (3), 1134-1136. e3, 2020
Focal distribution of hepatitis C virus RNA in infected livers
JD Stiffler, M Nguyen, JA Sohn, C Liu, D Kaplan, C Seeger
PloS one 4 (8), e6661, 2009
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