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Mei Y. Speer
Mei Y. Speer
Verified email at uw.edu
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Year
Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers
SA Steitz, MY Speer, G Curinga, HY Yang, P Haynes, R Aebersold, ...
Circulation research 89 (12), 1147-1154, 2001
10342001
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness
AL Durham, MY Speer, M Scatena, CM Giachelli, CM Shanahan
Cardiovascular research 114 (4), 590-600, 2018
8102018
Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries
MY Speer, HY Yang, T Brabb, E Leaf, A Look, WL Lin, A Frutkin, D Dichek, ...
Circulation research 104 (6), 733-741, 2009
6542009
Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification
SA Steitz, MY Speer, MD McKee, L Liaw, M Almeida, H Yang, ...
The American journal of pathology 161 (6), 2035-2046, 2002
5852002
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein–deficient mice: evidence for osteopontin as an inducible inhibitor of vascular …
MY Speer, MD McKee, RE Guldberg, L Liaw, HY Yang, E Tung, ...
The Journal of experimental medicine 196 (8), 1047-1055, 2002
4502002
Regulation of vascular calcification: roles of phosphate and osteopontin
CM Giachelli, MY Speer, X Li, RM Rajachar, H Yang
Circulation research 96 (7), 717-722, 2005
4152005
Regulation of cardiovascular calcification
MY Speer, CM Giachelli
Cardiovascular Pathology 13 (2), 63-70, 2004
3052004
Activation of paracrine TGF‐β1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase
KA Lindstedt, Y Wang, N Shiota, J Saarinen, M Hyytiäinen, JO Kokkonen, ...
The FASEB Journal 15 (8), 1377-1388, 2001
2542001
Activation of paracrine TGF‐β1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase
KA Lindstedt, Y Wang, N Shiota, J Saarinen, M Hyytiäinen, JO Kokkonen, ...
The FASEB Journal 15 (8), 1377-1388, 2001
2542001
Smooth muscle cell plasticity: fact or fiction?
AT Nguyen, D Gomez, RD Bell, JH Campbell, AW Clowes, G Gabbiani, ...
Circulation research 112 (1), 17-22, 2013
2102013
Calcification of advanced atherosclerotic lesions in the innominate arteries of ApoE-deficient mice: potential role of chondrocyte-like cells
M Rattazzi, BJ Bennett, F Bea, EA Kirk, JL Ricks, M Speer, SM Schwartz, ...
Arteriosclerosis, thrombosis, and vascular biology 25 (7), 1420-1425, 2005
1872005
Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study
V Naik, EM Leaf, JH Hu, HY Yang, NB Nguyen, CM Giachelli, MY Speer
Cardiovascular research 94 (3), 545-554, 2012
1692012
Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis
MY Speer, X Li, PG Hiremath, CM Giachelli
Journal of cellular biochemistry 110 (4), 935-947, 2010
1622010
Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions
MJ Leskinen, KA Lindstedt, Y Wang, PT Kovanen
Arteriosclerosis, thrombosis, and vascular biology 23 (2), 238-243, 2003
1582003
Runx2 expression in smooth muscle cells is required for arterial medial calcification in mice
ME Lin, T Chen, EM Leaf, MY Speer, CM Giachelli
The American journal of pathology 185 (7), 1958-1969, 2015
1452015
Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro
MY Speer, YC Chien, M Quan, HY Yang, H Vali, MD McKee, CM Giachelli
Cardiovascular research 66 (2), 324-333, 2005
1452005
Runx2 deletion in smooth muscle cells inhibits vascular osteochondrogenesis and calcification but not atherosclerotic lesion formation
ME Lin, TM Chen, MC Wallingford, NB Nguyen, S Yamada, ...
Cardiovascular research 112 (2), 606-616, 2016
1262016
Mast cell chymase induces apoptosis of vascular smooth muscle cells
M Leskinen, Y Wang, D Leszczynski, KA Lindstedt, PT Kovanen
Arteriosclerosis, thrombosis, and vascular biology 21 (4), 516-522, 2001
1252001
Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-κB-mediated survival signaling
MJ Leskinen, HM Heikkilä, MY Speer, JK Hakala, M Laine, PT Kovanen, ...
Experimental cell research 312 (8), 1289-1298, 2006
942006
Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: transforming growth factor-β1-dependent and-independent effects
Y Wang, N Shiota, MJ Leskinen, KA Lindstedt, PT Kovanen
Arteriosclerosis, thrombosis, and vascular biology 21 (12), 1928-1933, 2001
862001
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