Smooth muscle cell phenotypic transition associated with calcification: upregulation of Cbfa1 and downregulation of smooth muscle lineage markers SA Steitz, MY Speer, G Curinga, HY Yang, P Haynes, R Aebersold, ... Circulation research 89 (12), 1147-1154, 2001 | 1034 | 2001 |
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness AL Durham, MY Speer, M Scatena, CM Giachelli, CM Shanahan Cardiovascular research 114 (4), 590-600, 2018 | 810 | 2018 |
Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries MY Speer, HY Yang, T Brabb, E Leaf, A Look, WL Lin, A Frutkin, D Dichek, ... Circulation research 104 (6), 733-741, 2009 | 654 | 2009 |
Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification SA Steitz, MY Speer, MD McKee, L Liaw, M Almeida, H Yang, ... The American journal of pathology 161 (6), 2035-2046, 2002 | 585 | 2002 |
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein–deficient mice: evidence for osteopontin as an inducible inhibitor of vascular … MY Speer, MD McKee, RE Guldberg, L Liaw, HY Yang, E Tung, ... The Journal of experimental medicine 196 (8), 1047-1055, 2002 | 450 | 2002 |
Regulation of vascular calcification: roles of phosphate and osteopontin CM Giachelli, MY Speer, X Li, RM Rajachar, H Yang Circulation research 96 (7), 717-722, 2005 | 415 | 2005 |
Regulation of cardiovascular calcification MY Speer, CM Giachelli Cardiovascular Pathology 13 (2), 63-70, 2004 | 305 | 2004 |
Activation of paracrine TGF‐β1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase KA Lindstedt, Y Wang, N Shiota, J Saarinen, M Hyytiäinen, JO Kokkonen, ... The FASEB Journal 15 (8), 1377-1388, 2001 | 254 | 2001 |
Activation of paracrine TGF‐β1 signaling upon stimulation and degranulation of rat serosal mast cells: a novel function for chymase KA Lindstedt, Y Wang, N Shiota, J Saarinen, M Hyytiäinen, JO Kokkonen, ... The FASEB Journal 15 (8), 1377-1388, 2001 | 254 | 2001 |
Smooth muscle cell plasticity: fact or fiction? AT Nguyen, D Gomez, RD Bell, JH Campbell, AW Clowes, G Gabbiani, ... Circulation research 112 (1), 17-22, 2013 | 210 | 2013 |
Calcification of advanced atherosclerotic lesions in the innominate arteries of ApoE-deficient mice: potential role of chondrocyte-like cells M Rattazzi, BJ Bennett, F Bea, EA Kirk, JL Ricks, M Speer, SM Schwartz, ... Arteriosclerosis, thrombosis, and vascular biology 25 (7), 1420-1425, 2005 | 187 | 2005 |
Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study V Naik, EM Leaf, JH Hu, HY Yang, NB Nguyen, CM Giachelli, MY Speer Cardiovascular research 94 (3), 545-554, 2012 | 169 | 2012 |
Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis MY Speer, X Li, PG Hiremath, CM Giachelli Journal of cellular biochemistry 110 (4), 935-947, 2010 | 162 | 2010 |
Mast cell chymase induces smooth muscle cell apoptosis by a mechanism involving fibronectin degradation and disruption of focal adhesions MJ Leskinen, KA Lindstedt, Y Wang, PT Kovanen Arteriosclerosis, thrombosis, and vascular biology 23 (2), 238-243, 2003 | 158 | 2003 |
Runx2 expression in smooth muscle cells is required for arterial medial calcification in mice ME Lin, T Chen, EM Leaf, MY Speer, CM Giachelli The American journal of pathology 185 (7), 1958-1969, 2015 | 145 | 2015 |
Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro MY Speer, YC Chien, M Quan, HY Yang, H Vali, MD McKee, CM Giachelli Cardiovascular research 66 (2), 324-333, 2005 | 145 | 2005 |
Runx2 deletion in smooth muscle cells inhibits vascular osteochondrogenesis and calcification but not atherosclerotic lesion formation ME Lin, TM Chen, MC Wallingford, NB Nguyen, S Yamada, ... Cardiovascular research 112 (2), 606-616, 2016 | 126 | 2016 |
Mast cell chymase induces apoptosis of vascular smooth muscle cells M Leskinen, Y Wang, D Leszczynski, KA Lindstedt, PT Kovanen Arteriosclerosis, thrombosis, and vascular biology 21 (4), 516-522, 2001 | 125 | 2001 |
Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-κB-mediated survival signaling MJ Leskinen, HM Heikkilä, MY Speer, JK Hakala, M Laine, PT Kovanen, ... Experimental cell research 312 (8), 1289-1298, 2006 | 94 | 2006 |
Mast cell chymase inhibits smooth muscle cell growth and collagen expression in vitro: transforming growth factor-β1-dependent and-independent effects Y Wang, N Shiota, MJ Leskinen, KA Lindstedt, PT Kovanen Arteriosclerosis, thrombosis, and vascular biology 21 (12), 1928-1933, 2001 | 86 | 2001 |