| High-potency ligands for DREADD imaging and activation in rodents and monkeys J Bonaventura, MAG Eldridge, F Hu, JL Gomez, M Sanchez-Soto, ... Nature communications 10 (1), 4627, 2019 | 145 | 2019 |
| Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays H Yano, A Bonifazi, M Xu, DA Guthrie, SN Schneck, AM Abramyan, ... Neuropharmacology 133, 264-275, 2018 | 61 | 2018 |
| Identification of a putative binding site critical for general anesthetic activation of TRPA1 HT Ton, TX Phan, AM Abramyan, L Shi, GP Ahern Proceedings of the National Academy of Sciences 114 (14), 3762-3767, 2017 | 56 | 2017 |
| The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter P Plenge, AM Abramyan, G Sørensen, A Mørk, P Weikop, U Gether, ... Nature Communications 11 (1), 1491, 2020 | 38 | 2020 |
| Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders AH Newman, J Cao, JD Keighron, CJ Jordan, GH Bi, Y Liang, ... Neuropsychopharmacology 44 (8), 1435-1444, 2019 | 38 | 2019 |
| The isomeric preference of an atypical dopamine transporter inhibitor contributes to its selection of the transporter conformation AM Abramyan, S Stolzenberg, Z Li, CJ Loland, F Noé, L Shi ACS Chemical Neuroscience 8 (8), 1735-1746, 2017 | 36 | 2017 |
| Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism JR Lane, AM Abramyan, P Adhikari, AC Keen, KH Lee, J Sanchez, ... Elife 9, e52189, 2020 | 32 | 2020 |
| The LeuT-fold neurotransmitter: sodium symporter MhsT has two substrate sites M Quick, AM Abramyan, P Wiriyasermkul, H Weinstein, L Shi, JA Javitch Proceedings of the National Academy of Sciences 115 (34), E7924-E7931, 2018 | 29 | 2018 |
| Computational prediction and rationalization, and experimental validation of handedness induction in helical aromatic oligoamide foldamers Z Liu, X Hu, AM Abramyan, Á Mészáros, M Csékei, A Kotschy, I Huc, ... Chemistry–A European Journal 23 (15), 3605-3615, 2017 | 24 | 2017 |
| Helix handedness inversion in arylamide foldamers: elucidation and free energy profile of a hopping mechanism AM Abramyan, Z Liu, V Pophristic Chemical communications 52 (4), 669-672, 2016 | 24 | 2016 |
| Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics AM Abramyan, RD Slack, S Meena, BA Davis, AH Newman, SK Singh, ... Neuropharmacology 161, 107411, 2019 | 21 | 2019 |
| The E2.65A mutation disrupts dynamic binding poses of SB269652 at the dopamine D2 and D3 receptors RK Verma, AM Abramyan, M Michino, RB Free, DR Sibley, JA Javitch, ... PLoS Computational Biology 14 (1), e1005948, 2018 | 20 | 2018 |
| Structure–activity relationship studies on a series of 3α-[Bis (4-fluorophenyl) methoxy] tropanes and 3α-[Bis (4-fluorophenyl) methylamino] tropanes as novel atypical dopamine … MF Zou, J Cao, AM Abramyan, T Kopajtic, C Zanettini, DA Guthrie, R Rais, ... Journal of medicinal chemistry 60 (24), 10172-10187, 2017 | 18 | 2017 |
| Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D3 Dopamine Receptor Agonist AE Moritz, RB Free, WS Weiner, EO Akano, D Gandhi, A Abramyan, ... Journal of medicinal chemistry 63 (10), 5526-5567, 2020 | 17 | 2020 |
| The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor AM Abramyan, H Yano, M Xu, L Liu, S Naing, AD Fant, L Shi Computational and Structural Biotechnology Journal 18, 199-206, 2020 | 17 | 2020 |
| Helical arylamide foldamers: structure prediction by molecular dynamics simulations Z Liu, AM Abramyan, V Pophristic New Journal of Chemistry 39 (5), 3229-3240, 2015 | 17 | 2015 |
| The action of a negative allosteric modulator at the dopamine D2 receptor is dependent upon sodium ions CJ Draper-Joyce, RK Verma, M Michino, J Shonberg, A Kopinathan, ... Scientific Reports 8 (1), 1208, 2018 | 16 | 2018 |
| Chemogenetic ligands for translational neurotheranostics J Bonaventura, MA Eldridge, F Hu, JL Gomez, M Sanchez-Soto, ... bioRxiv, 487637, 2018 | 12 | 2018 |
| A novel Bromine-Containing paroxetine analogue provides mechanistic clues for binding ambiguity at the central primary binding site of the serotonin transporter RD Slack, AM Abramyan, H Tang, S Meena, BA Davis, A Bonifazi, ... ACS chemical neuroscience 10 (9), 3946-3952, 2019 | 11 | 2019 |
| Mechanistic and dynamic insights into ligand encapsulation by helical arylamide foldamers AM Abramyan, Z Liu, V Pophristic Physical Chemistry Chemical Physics 16 (38), 20406-20410, 2014 | 11 | 2014 |
Jhenny GalanTexas A&M University at GalvestonVerified email at tamug.edu
