Georgina S. Butler
Georgina S. Butler
Research Associate, Center for Blood Research, University of British Columbia, Canada.
Verified email at ubc.ca
TitleCited byYear
The TIMP2 membrane type 1 metalloproteinase “receptor” regulates the concentration and efficient activation of progelatinase AA kinetic study
GS Butler, MJ Butler, SJ Atkinson, H Will, T Tamura, SS van Westrum, ...
Journal of Biological Chemistry 273 (2), 871-880, 1998
6831998
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell-derived factor-1
GA McQuibban, GS Butler, JH Gong, L Bendall, C Power, I Clark-Lewis, ...
Journal of Biological Chemistry 276 (47), 43503-43508, 2001
6732001
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation Regulation by TIMP-2 …
H Will, SJ Atkinson, GS Butler, B Smith, G Murphy
Journal of Biological Chemistry 271 (29), 17119-17123, 1996
6401996
Mechanisms for pro matrix metalloproteinase activation
G MURPHY, H STANTON, S COWELL, G BUTLER, V KNÄUPER, ...
Apmis 107 (1‐6), 38-44, 1999
5271999
Membrane‐type matrix metalloproteinases 1 and 2 exhibit broad‐spectrum proteolytic capacities comparable to many matrix metalloproteinases
MP D'ortho, H Will, S Atkinson, G Butler, A Messent, J Gavrilovic, B Smith, ...
European Journal of Biochemistry 250 (3), 751-757, 1997
4911997
HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration
K Zhang, GA McQuibban, C Silva, GS Butler, JB Johnston, J Holden, ...
Nature neuroscience 6 (10), 1064, 2003
3262003
Matrix metalloproteinase proteomics: substrates, targets, and therapy
CJ Morrison, GS Butler, D Rodríguez, CM Overall
Current opinion in cell biology 21 (5), 645-653, 2009
2492009
Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics
A Prudova, U auf dem Keller, GS Butler, CM Overall
Molecular & Cellular Proteomics 9 (5), 894-911, 2010
2232010
Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway
CJ Morrison, GS Butler, HF Bigg, CR Roberts, PD Soloway, CM Overall
Journal of Biological Chemistry 276 (50), 47402-47410, 2001
2152001
Updated biological roles for matrix metalloproteinases and new “intracellular” substrates revealed by degradomics
GS Butler, CM Overall
Biochemistry 48 (46), 10830-10845, 2009
2142009
Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth …
RA Dean, GS Butler, Y Hamma-Kourbali, J Delbé, DR Brigstock, J Courty, ...
Molecular and cellular biology 27 (24), 8454-8465, 2007
1982007
Membrane‐type‐2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases
GS Butler, H Will, SJ Atkinson, G Murphy
European journal of biochemistry 244 (2), 653-657, 1997
1941997
Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase
HF Bigg, CJ Morrison, GS Butler, MA Bogoyevitch, Z Wang, PD Soloway, ...
Cancer research 61 (9), 3610-3618, 2001
1702001
A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity
DJ Marchant, CL Bellac, TJ Moraes, SJ Wadsworth, A Dufour, GS Butler, ...
Nature medicine 20 (5), 493, 2014
1602014
Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding
GS Butler, RA Dean, EM Tam, CM Overall
Molecular and cellular biology 28 (15), 4896-4914, 2008
1552008
Characterization of the Distinct Collagen Binding, Helicase and Cleavage Mechanisms of Matrix Metalloproteinase 2 and 14 (Gelatinase A and MT1-MMP) THE DIFFERENTIAL ROLES OF …
EM Tam, TR Moore, GS Butler, CM Overall
Journal of Biological Chemistry 279 (41), 43336-43344, 2004
1552004
Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin c domain the ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits …
EM Tam, YI Wu, GS Butler, MS Stack, CM Overall
Journal of Biological Chemistry 277 (41), 39005-39014, 2002
1542002
Metadegradomics: toward in vivo quantitative degradomics of proteolytic post-translational modifications of the cancer proteome
A Doucet, GS Butler, D Rodríguez, A Prudova, CM Overall
Molecular & Cellular Proteomics 7 (10), 1925-1951, 2008
1422008
Human Tissue Inhibitor of Metalloproteinases 3 Interacts with Both the N-and C-terminal Domains of Gelatinases A and B REGULATION BY POLYANIONS
GS Butler, SS Apte, F Willenbrock, G Murphy
Journal of Biological Chemistry 274 (16), 10846-10851, 1999
1411999
Evaluation of some newer matrix metalloproteinases
G Murphy, V KNÄUPER, S Cowell, R Hembry, H Stanton, G Butler, ...
Annals of the New York Academy of Sciences 878 (1), 25-39, 1999
1271999
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