charles eberhart
charles eberhart
Professor of Pathology, Ophthalmology and Oncology, Johns Hopkins University School of Medicine
Verified email at jhmi.edu
TitleCited byYear
Molecular subgroups of medulloblastoma: the current consensus
MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ...
Acta neuropathologica 123 (4), 465-472, 2012
11402012
Medulloblastoma comprises four distinct molecular variants
PA Northcott, A Korshunov, H Witt, T Hielscher, CG Eberhart, S Mack, ...
Journal of Clinical Oncology 29 (11), 1408, 2011
9932011
Medulloblastoma growth inhibition by hedgehog pathway blockade
DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ...
Science 297 (5586), 1559-1561, 2002
9202002
Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
X Fan, W Matsui, L Khaki, D Stearns, J Chun, YM Li, CG Eberhart
Cancer research 66 (15), 7445-7452, 2006
7112006
Altered telomeres in tumors with ATRX and DAXX mutations
CM Heaphy, RF De Wilde, Y Jiao, AP Klein, BH Edil, C Shi, C Bettegowda, ...
Science 333 (6041), 425-425, 2011
6902011
Cyclopamine‐mediated hedgehog pathway inhibition depletes stem‐like cancer cells in glioblastoma
EE Bar, A Chaudhry, A Lin, X Fan, K Schreck, W Matsui, S Piccirillo, ...
Stem cells 25 (10), 2524-2533, 2007
6472007
NOTCH pathway blockade depletes CD133‐positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
X Fan, L Khaki, TS Zhu, ME Soules, CE Talsma, N Gul, C Koh, J Zhang, ...
Stem cells 28 (1), 5-16, 2010
6232010
Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation
BW Purow, RM Haque, MW Noel, Q Su, MJ Burdick, J Lee, T Sundaresan, ...
Cancer research 65 (6), 2353-2363, 2005
6152005
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
5682012
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of Clinical Oncology 29 (11), 1424, 2011
5532011
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927, 2013
4602013
The neurobiology of autism
CA Pardo, CG Eberhart
Brain Pathology 17 (4), 434-447, 2007
4602007
Notch1 and notch2 have opposite effects on embryonal brain tumor growth
X Fan, I Mikolaenko, I Elhassan, XZ Ni, Y Wang, D Ball, DJ Brat, A Perry, ...
Cancer research 64 (21), 7787-7793, 2004
4602004
Meiotic cell cycle requirement for a fly homologue of human Deleted in Azoospermia
CG Eberhart, JZ Maines, SA Wasserman
Nature 381 (6585), 783, 1996
4521996
Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease
CH Kwon, X Zhu, J Zhang, LL Knoop, R Tharp, RJ Smeyne, CG Eberhart, ...
Nature genetics 29 (4), 404, 2001
4442001
I nternational S ociety of N europathology‐H aarlem C onsensus G uidelines for N ervous S ystem T umor C lassification and G rading
DN Louis, A Perry, P Burger, DW Ellison, G Reifenberger, A von Deimling, ...
Brain pathology 24 (5), 429-435, 2014
4142014
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
PA Northcott, Y Nakahara, X Wu, L Feuk, DW Ellison, S Croul, S Mack, ...
Nature genetics 41 (4), 465, 2009
3972009
Clonal selection drives genetic divergence of metastatic medulloblastoma
X Wu, PA Northcott, A Dubuc, AJ Dupuy, DJH Shih, H Witt, S Croul, ...
Nature 482 (7386), 529, 2012
3632012
Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis.
DH Castrillon, P Gönczy, S Alexander, R Rawson, CG Eberhart, ...
Genetics 135 (2), 489-505, 1993
3571993
A dense poly (ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue
EA Nance, GF Woodworth, KA Sailor, TY Shih, Q Xu, G Swaminathan, ...
Science translational medicine 4 (149), 149ra119-149ra119, 2012
3412012
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