| Cytoplasmic chromatin triggers inflammation in senescence and cancer Z Dou, K Ghosh, MG Vizioli, J Zhu, P Sen, KJ Wangensteen, J Simithy, ... Nature 550 (7676), 402-406, 2017 | 1019 | 2017 |
| Autophagy mediates degradation of nuclear lamina Z Dou, C Xu, G Donahue, T Shimi, JA Pan, J Zhu, A Ivanov, BC Capell, ... Nature 527 (7576), 105-109, 2015 | 605 | 2015 |
| Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth J Zhu, MA Sammons, G Donahue, Z Dou, M Vedadi, M Getlik, ... Nature 525 (7568), 206-211, 2015 | 489 | 2015 |
| Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function N Jaber, Z Dou, JS Chen, J Catanzaro, YP Jiang, LM Ballou, E Selinger, ... Proceedings of the National Academy of Sciences 109 (6), 2003-2008, 2012 | 438 | 2012 |
| SIRT1 is downregulated by autophagy in senescence and ageing C Xu, L Wang, P Fozouni, G Evjen, V Chandra, J Jiang, C Lu, M Nicastri, ... Nature cell biology 22 (10), 1170-1179, 2020 | 351 | 2020 |
| Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence MG Vizioli, T Liu, KN Miller, NA Robertson, K Gilroy, AB Lagnado, ... Genes & development 34 (5-6), 428-445, 2020 | 226 | 2020 |
| TRIM21 ubiquitylates SQSTM1/p62 and suppresses protein sequestration to regulate redox homeostasis JA Pan, Y Sun, YP Jiang, AJ Bott, N Jaber, Z Dou, B Yang, JS Chen, ... Molecular cell 61 (5), 720-733, 2016 | 222 | 2016 |
| MLL1 is essential for the senescence-associated secretory phenotype BC Capell, AM Drake, J Zhu, PP Shah, Z Dou, J Dorsey, DF Simola, ... Genes & development 30 (3), 321-336, 2016 | 145 | 2016 |
| Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex NC McKnight, Y Zhong, MS Wold, S Gong, GR Phillips, Z Dou, Y Zhao, ... PLoS genetics 10 (10), e1004626, 2014 | 140 | 2014 |
| Class IA PI3K p110β subunit promotes autophagy through Rab5 small GTPase in response to growth factor limitation Z Dou, JA Pan, HA Dbouk, LM Ballou, JL DeLeon, Y Fan, JS Chen, ... Molecular cell 50 (1), 29-42, 2013 | 137 | 2013 |
| TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I–like receptor-mediated innate immune response Z Zhou, X Jia, Q Xue, Z Dou, Y Ma, Z Zhao, Z Jiang, B He, Q Jin, J Wang Proceedings of the National Academy of Sciences 111 (2), E245-E254, 2014 | 134 | 2014 |
| Inhibition of protein degradation induces apoptosis through a microtubule-associated protein 1 light chain 3-mediated activation of caspase-8 at intracellular membranes JA Pan, E Ullman, Z Dou, WX Zong Molecular and cellular biology 31 (15), 3158-3170, 2011 | 106 | 2011 |
| Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence P Sen, Y Lan, CY Li, S Sidoli, G Donahue, Z Dou, B Frederick, Q Chen, ... Molecular cell 73 (4), 684-698. e8, 2019 | 104 | 2019 |
| The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy Z Dou, M Chattopadhyay, JA Pan, JL Guerriero, YP Jiang, LM Ballou, ... Journal of cell biology 191 (4), 827-843, 2010 | 103 | 2010 |
| Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus N Jaber, N Mohd-Naim, Z Wang, JL DeLeon, S Kim, H Zhong, ... Journal of cell science 129 (23), 4424-4435, 2016 | 84 | 2016 |
| Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform KJ Wangensteen, YJ Wang, Z Dou, AW Wang, E Mosleh‐Shirazi, ... Hepatology 68 (2), 663-676, 2018 | 73 | 2018 |
| Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV-2 infection Z Zhou, X Zhang, X Lei, X Xiao, T Jiao, R Ma, X Dong, Q Jiang, W Wang, ... Signal Transduction and Targeted Therapy 6 (1), 382, 2021 | 66 | 2021 |
| SIRT1–a new mammalian substrate of nuclear autophagy L Wang, C Xu, T Johansen, SL Berger, Z Dou Autophagy 17 (2), 593-595, 2021 | 65 | 2021 |
| Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 57 | 2023 |
| Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress Z Dou, A Ivanov, PD Adams, SL Berger Autophagy 12 (8), 1416-1417, 2016 | 51 | 2016 |
