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Lulzim Shkreta
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hnRNP proteins and splicing control
R Martinez-Contreras, P Cloutier, L Shkreta, JF Fisette, T Revil, B Chabot
Alternative splicing in the postgenomic era, 123-147, 2007
4812007
Defective control of pre–messenger RNA splicing in human disease
B Chabot, L Shkreta
Journal of Cell Biology 212 (1), 13-27, 2016
2332016
The RNA splicing response to DNA damage
L Shkreta, B Chabot
Biomolecules 5 (4), 2935-2977, 2015
1472015
Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators
L Michelle, A Cloutier, J Toutant, L Shkreta, P Thibault, M Durand, ...
Molecular and cellular biology 32 (5), 954-967, 2012
1362012
TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis
JE Deshaies, L Shkreta, AJ Moszczynski, H Sidibé, S Semmler, A Fouillen, ...
Brain 141 (5), 1320-1333, 2018
1322018
Insulin-like growth factor binding protein-5 (IGFBP-5) potentially regulates programmed cell death and plasminogen activation in the mammary gland
E Tonner, G Allan, L Shkreta, J Webster, C Bruce, A Whitelaw, DJ Flint
Biology of the Mammary Gland, 45-53, 2002
992002
Antagonistic effects of the SRp30c protein and cryptic 5′ splice sites on the alternative splicing of the apoptotic regulator Bcl-x
P Cloutier, J Toutant, L Shkreta, S Goekjian, T Revil, B Chabot
Journal of Biological Chemistry 283 (31), 21315-21324, 2008
882008
Protein kinase C-dependent control of Bcl-x alternative splicing
T Revil, J Toutant, L Shkreta, D Garneau, P Cloutier, B Chabot
Molecular and cellular biology, 2007
872007
Anticancer drugs affect the alternative splicing of Bcl-x and other human apoptotic genes
L Shkreta, U Froehlich, ER Paquet, J Toutant, SA Elela, B Chabot
Molecular cancer therapeutics 7 (6), 1398-1409, 2008
862008
The effect of plasminogen activator inhibitor type 1 on apoptosis
DJ Schneider, Y Chen, BE Sobel
Thrombosis and haemostasis 100 (12), 1037-1040, 2008
752008
hnRNP I/PTB can antagonize the splicing repressor activity of SRp30c
C Paradis, P Cloutier, L Shkreta, J Toutant, K Klarskov, B Chabot
Rna 13 (8), 1287-1300, 2007
732007
SRSF10 connects DNA damage to the alternative splicing of transcripts encoding apoptosis, cell-cycle control, and DNA repair factors
L Shkreta, J Toutant, M Durand, JL Manley, B Chabot
Cell reports 17 (8), 1990-2003, 2016
682016
The DNA damage response pathway regulates the alternative splicing of the apoptotic mediator Bcl-x
L Shkreta, L Michelle, J Toutant, ML Tremblay, B Chabot
Journal of biological chemistry 286 (1), 331-340, 2011
652011
Cancer-associated perturbations in alternative pre-messenger RNA splicing
L Shkreta, B Bell, T Revil, JP Venables, P Prinos, SA Elela, B Chabot
RNA and Cancer, 41-94, 2013
632013
Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication
L Shkreta, M Blanchette, J Toutant, E Wilhelm, B Bell, BA Story, ...
Nucleic acids research 45 (7), 4051-4067, 2017
432017
Redirecting splicing with bifunctional oligonucleotides
JP Brosseau, JF Lucier, AA Lamarche, L Shkreta, D Gendron, E Lapointe, ...
Nucleic acids research 42 (6), e40-e40, 2014
412014
hnRNP A1/A2 and Sam68 collaborate with SRSF10 to control the alternative splicing response to oxaliplatin-mediated DNA damage
A Cloutier, L Shkreta, J Toutant, M Durand, P Thibault, B Chabot
Scientific reports 8 (1), 2206, 2018
362018
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells
M Sohail, L Shkreta, J Toutant, S Rabea, JP Babeu, C Huard, ...
NAR cancer 3 (2), zcab019, 2021
152021
Interplay between CMGC kinases targeting SR proteins and viral replication: splicing and beyond
F Pastor, L Shkreta, B Chabot, D Durantel, A Salvetti
Frontiers in Microbiology 12, 658721, 2021
132021
Pre-mRNA alternative splicing in cancer: functional impact, molecular mechanisms and therapeutic perspectives
T Revil, L Shkreta, B Chabot
Bulletin du Cancer 93 (9), 909-919, 2006
132006
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Articles 1–20