Apolipoprotein E: cholesterol transport protein with expanding role in cell biology RW Mahley Science 240 (4852), 622-630, 1988 | 5115 | 1988 |
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2476 | 2010 |
Apolipoprotein E: far more than a lipid transport protein RW Mahley, SC Rall Jr Annual review of genomics and human genetics 1 (1), 507-537, 2000 | 2163 | 2000 |
Plasma lipoproteins: apolipoprotein structure and function. RW Mahley, TL Innerarity, SC Rall Jr, KH Weisgraber Journal of lipid research 25 (12), 1277-1294, 1984 | 1647 | 1984 |
Ancient human genomes suggest three ancestral populations for present-day Europeans I Lazaridis, N Patterson, A Mittnik, G Renaud, S Mallick, K Kirsanow, ... Nature 513 (7518), 409-413, 2014 | 1486 | 2014 |
The Simons genome diversity project: 300 genomes from 142 diverse populations S Mallick, H Li, M Lipson, I Mathieson, M Gymrek, F Racimo, M Zhao, ... Nature 538 (7624), 201-206, 2016 | 1382 | 2016 |
Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer’s disease RW Mahley, KH Weisgraber, Y Huang Proceedings of the National Academy of Sciences 103 (15), 5644-5651, 2006 | 1211 | 2006 |
Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro BP Nathan, S Bellosta, DA Sanan, KH Weisgraber, RW Mahley, RE Pitas Science 264 (5160), 850-852, 1994 | 1010 | 1994 |
Human apolipoprotein E. The complete amino acid sequence. SC Rall Jr, KH Weisgraber, RW Mahley Journal of Biological Chemistry 257 (8), 4171-4178, 1982 | 1010 | 1982 |
Lipoprotein receptors and cholesterol homeostasis RW Mahley, TL Innerarity Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 737 (2), 197-222, 1983 | 1005 | 1983 |
Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. JK Boyles, RE Pitas, E Wilson, RW Mahley, JM Taylor The Journal of clinical investigation 76 (4), 1501-1513, 1985 | 983 | 1985 |
Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins RE Pitas, JK Boyles, SH Lee, D Foss, RW Mahley Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism 917 (1), 148-161, 1987 | 885 | 1987 |
Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E C Wilson, MR Wardell, KH Weisgraber, RW Mahley, DA Agard Science 252 (5014), 1817-1822, 1991 | 870 | 1991 |
Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E RW Mahley, ZS Ji Journal of lipid research 40 (1), 1-16, 1999 | 868 | 1999 |
Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site. KH Weisgraber, TL Innerarity, RW Mahley Journal of Biological Chemistry 257 (5), 2518-2521, 1982 | 833 | 1982 |
Complete protein sequence and identification of structural domains of human apolipoprotein B TJ Knott, RJ Pease, LM Powell, SC Wallis, SC Rall Jr, TL Innerarity, ... Nature 323 (6090), 734-738, 1986 | 758 | 1986 |
Expression of apolipoprotein E during nerve degeneration and regeneration. MJ Ignatius, PJ Gebicke-Härter, JH Skene, JW Schilling, KH Weisgraber, ... Proceedings of the National Academy of Sciences 83 (4), 1125-1129, 1986 | 732 | 1986 |
Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts. KH Weisgraber, TL Innerarity, RW Mahley Journal of Biological Chemistry 253 (24), 9053-9062, 1978 | 725 | 1978 |
Meta-analysis and imputation refines the association of 15q25 with smoking quantity JZ Liu, F Tozzi, DM Waterworth, SG Pillai, P Muglia, L Middleton, ... Nature genetics 42 (5), 436-440, 2010 | 718 | 2010 |
Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases Y Huang, RW Mahley Neurobiology of disease 72, 3-12, 2014 | 700 | 2014 |