| Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of A lzheimer's Disease C Tapia‐Rojas, F Aranguiz, L Varela‐Nallar, NC Inestrosa Brain Pathology 26 (1), 62-74, 2016 | 196 | 2016 |
| Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics A Carreras-Sureda, F Jaña, H Urra, S Durand, DE Mortenson, A Sagredo, ... Nature cell biology 21 (6), 755-767, 2019 | 187 | 2019 |
| It’s all about tau C Tapia-Rojas, F Cabezas-Opazo, CA Deaton, EH Vergara, ... Progress in neurobiology 175, 54-76, 2019 | 170 | 2019 |
| Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease ÁO Ardiles, CC Tapia-Rojas, M Mandal, F Alexandre, A Kirkwood, ... Proceedings of the National Academy of Sciences 109 (34), 13835-13840, 2012 | 153 | 2012 |
| Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents E Viayna, I Sola, M Bartolini, A De Simone, C Tapia-Rojas, FG Serrano, ... Journal of medicinal chemistry 57 (6), 2549-2567, 2014 | 152 | 2014 |
| Loss of canonical Wnt signaling is involved in the pathogenesis of Alzheimer's disease C Tapia-Rojas, NC Inestrosa Neural regeneration research 13 (10), 1705, 2018 | 115 | 2018 |
| Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice FG Serrano, C Tapia-Rojas, FJ Carvajal, J Hancke, W Cerpa, ... Molecular neurodegeneration 9 (1), 61, 2014 | 111 | 2014 |
| Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral … C Tapia-Rojas, CB Lindsay, C Montecinos-Oliva, MS Arrazola, ... Molecular neurodegeneration 10 (1), 62, 2015 | 96 | 2015 |
| Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK-3β in vivo C Tapia-Rojas, A Schüller, CB Lindsay, RC Ureta, C Mejías-Reyes, ... Biochemical Journal 466 (2), 415-430, 2015 | 86 | 2015 |
| Wnt signaling loss accelerates the appearance of neuropathological hallmarks of Alzheimer's disease in J20‐APP transgenic and wild‐type mice C Tapia‐Rojas, NC Inestrosa Journal of neurochemistry 144 (4), 443-465, 2018 | 80 | 2018 |
| Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid‐β (Aβ)42 peptides C Tapia‐Rojas, PV Burgos, NC Inestrosa Journal of neurochemistry 139 (6), 1175-1191, 2016 | 79 | 2016 |
| Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus C Jara, A Aránguiz, W Cerpa, C Tapia-Rojas, RA Quintanilla Redox biology 18, 279-294, 2018 | 74 | 2018 |
| Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect … NC Inestrosa, C Tapia-Rojas, TN Griffith, FJ Carvajal, MJ Benito, ... Translational psychiatry 1 (7), e20-e20, 2011 | 74 | 2011 |
| Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease NC Inestrosa, FJ Carvajal, JM Zolezzi, C Tapia-Rojas, F Serrano, ... Journal of Alzheimer's Disease 33 (4), 941-959, 2013 | 73 | 2013 |
| Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss MA Olesen, AK Torres, C Jara, MP Murphy, C Tapia-Rojas Redox Biology, 101558, 2020 | 71 | 2020 |
| Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment C Tapia-Rojas, FJ Carvajal, RG Mira, C Arce, JM Lerma-Cabrera, ... Molecular neurobiology 55 (5), 4473-4491, 2018 | 66 | 2018 |
| Andrographolide stimulates neurogenesis in the adult hippocampus L Varela-Nallar, SB Arredondo, C Tapia-Rojas, J Hancke, NC Inestrosa Neural plasticity 2015, 2015 | 62 | 2015 |
| Alzheimer’s disease-related protein expression in the retina of Octodon degus LY Du, LYL Chang, AO Ardiles, C Tapia-Rojas, J Araya, NC Inestrosa, ... PLoS One 10 (8), 2015 | 51 | 2015 |
| Pathologically phosphorylated tau at S396/404 (PHF-1) is accumulated inside of hippocampal synaptic mitochondria of aged Wild-type mice AK Torres, C Jara, MA Olesen, C Tapia-Rojas Scientific Reports 11 (1), 1-17, 2021 | 45 | 2021 |
| Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease NC Inestrosa, JA Ríos, P Cisternas, C Tapia‐Rojas, DS Rivera, N Braidy, ... Brain Pathology 25 (6), 679-691, 2015 | 45 | 2015 |
