Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway F Lessard, S Igelmann, C Trahan, G Huot, E Saint-Germain, L Mignacca, ... Nature cell biology 20 (7), 789-799, 2018 | 134 | 2018 |
The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis S Granneman, CY Lin, EA Champion, MR Nandineni, C Zorca, ... Nucleic acids research 34 (10), 3189-3199, 2006 | 79 | 2006 |
Oct-1 regulates IL-17 expression by directing interchromosomal associations in conjunction with CTCF in T cells LK Kim, E Esplugues, CE Zorca, F Parisi, Y Kluger, TH Kim, NJ Galjart, ... Molecular cell 54 (1), 56-66, 2014 | 56 | 2014 |
Single-cell profiling reveals that eRNA accumulation at enhancer–promoter loops is not required to sustain transcription S Rahman, CE Zorca, T Traboulsi, E Noutahi, MR Krause, S Mader, ... Nucleic acids research 45 (6), 3017-3030, 2017 | 53 | 2017 |
Rapid macropinocytic transfer of α-synuclein to lysosomes A Bayati, E Banks, C Han, W Luo, WE Reintsch, CE Zorca, I Shlaifer, ... Cell Reports 40 (3), 2022 | 35 | 2022 |
Myosin VI regulates gene pairing and transcriptional pause release in T cells CE Zorca, LK Kim, YJ Kim, MR Krause, D Zenklusen, CG Spilianakis, ... Proceedings of the National Academy of Sciences 112 (13), E1587-E1593, 2015 | 31 | 2015 |
Applying hiPSCs and biomaterials towards an understanding and treatment of traumatic brain injury M Lacalle-Aurioles, C Cassel de Camps, CE Zorca, LK Beitel, TM Durcan Frontiers in Cellular Neuroscience 14, 594304, 2020 | 21 | 2020 |
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson’s disease K Senkevich, CE Zorca, A Dworkind, U Rudakou, E Somerville, E Yu, ... Brain 146 (5), 1859-1872, 2023 | 18 | 2023 |
Hallmarks and molecular tools for the study of mitophagy in Parkinson’s disease T Goiran, MA Eldeeb, CE Zorca, EA Fon Cells 11 (13), 2097, 2022 | 16 | 2022 |
Tom20 gates PINK1 activity and mediates its tethering of the TOM and TIM23 translocases upon mitochondrial stress MA Eldeeb, AN Bayne, A Fallahi, T Goiran, EJ MacDougall, A Soumbasis, ... Proceedings of the National Academy of Sciences 121 (10), e2313540121, 2024 | 12 | 2024 |
Combining NGN2 programming and dopaminergic patterning for a rapid and efficient generation of hiPSC-derived midbrain neurons R Sheta, M Teixeira, W Idi, M Pierre, A de Rus Jacquet, V Emond, ... Scientific Reports 12 (1), 17176, 2022 | 12 | 2022 |
Fine‐tuning ER‐phagy by post‐translational modifications MA Eldeeb, CE Zorca, MA Ragheb, FB Rashidi, DS Salah El‐Din Bioessays 43 (2), 2000212, 2021 | 10 | 2021 |
Extracellular protein degradation via the lysosome MA Eldeeb, CE Zorca, T Goiran Communications Chemistry 3 (1), 149, 2020 | 10 | 2020 |
Bicentennial: The legacy of a founding father of modern cell biology: George Emil Palade (1912-2008) SM Zorca, CE Zorca The Yale Journal of Biology and Medicine 84 (2), 113, 2011 | 9 | 2011 |
Targeting cancer cells via N-degron-based PROTACs MA Eldeeb, CE Zorca, RP Fahlman Endocrinology 161 (12), bqaa185, 2020 | 4 | 2020 |
A dual hit of α-synuclein internalization and immune challenge leads to the formation and maintenance of Lewy body-like inclusions in human dopaminergic neurons A Bayati, R Ayoubi, A Aguila, CE Zorca, C Han, E Banks, ... bioRxiv, 2023.05. 29.542776, 2023 | 2 | 2023 |
Multifaceted targeted protein degradation systems for different cellular compartments CE Zorca, A Fallahi, S Luo, MA Eldeeb BioEssays 44 (6), 2200008, 2022 | 2 | 2022 |
Dephosphorylation Targeting Chimaera (DEPTAC): Targeting Tau Proteins in Tauopathies A Soumbasis, MA Eldeeb, MA Ragheb, CE Zorca Current Protein and Peptide Science 23 (3), 129-132, 2022 | 2 | 2022 |
Modeling Parkinson’s disease pathology in human dopaminergic neurons by sequential exposure to α-synuclein fibrils and proinflammatory cytokines A Bayati, R Ayoubi, A Aguila, CE Zorca, G Deyab, C Han, SJ Recinto, ... Nature Neuroscience, 1-16, 2024 | 1 | 2024 |
GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson’s K Senkevich, CE Zorca, A Dworkind | | 2022 |