Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C (high) monocytes K Movahedi, D Laoui, C Gysemans, M Baeten, G Stangé, ... Cancer research 70 (14), 5728-5739, 2010 | 1252 | 2010 |
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF C Rolny, M Mazzone, S Tugues, D Laoui, I Johansson, C Coulon, ... Cancer cell 19 (1), 31-44, 2011 | 778 | 2011 |
Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity A Casazza, D Laoui, M Wenes, S Rizzolio, N Bassani, M Mambretti, ... Cancer cell 24 (6), 695-709, 2013 | 619 | 2013 |
Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade M Schmittnaegel, N Rigamonti, E Kadioglu, A Cassará, C Wyser Rmili, ... Science translational medicine 9 (385), eaak9670, 2017 | 481 | 2017 |
A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling J Qian, S Olbrecht, B Boeckx, H Vos, D Laoui, E Etlioglu, E Wauters, ... Cell research 30 (9), 745-762, 2020 | 429 | 2020 |
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population D Laoui, E Van Overmeire, G Di Conza, C Aldeni, J Keirsse, Y Morias, ... Cancer research 74 (1), 24-30, 2014 | 426 | 2014 |
Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions D Laoui, K Movahedi, E Van Overmeire, J Van den Bossche, E Schouppe, ... International Journal of Developmental Biology 55 (7-8-9), 861-867, 2011 | 368 | 2011 |
Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages K Movahedi, S Schoonooghe, D Laoui, I Houbracken, W Waelput, ... Cancer research 72 (16), 4165-4177, 2012 | 318 | 2012 |
Molecular profiling reveals a tumor-promoting phenotype of monocytes and macrophages in human cancer progression M Chittezhath, MK Dhillon, JY Lim, D Laoui, IN Shalova, YL Teo, J Chen, ... Immunity 41 (5), 815-829, 2014 | 288 | 2014 |
The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity D Laoui, J Keirsse, Y Morias, E Van Overmeire, X Geeraerts, Y Elkrim, ... Nature communications 7 (1), 13720, 2016 | 257 | 2016 |
Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity C Baer, ML Squadrito, D Laoui, D Thompson, SK Hansen, A Kiialainen, ... Nature cell biology 18 (7), 790-802, 2016 | 248 | 2016 |
M-CSF and GM-CSF receptor signaling differentially regulate monocyte maturation and macrophage polarization in the tumor microenvironment E Van Overmeire, B Stijlemans, F Heymann, J Keirsse, Y Morias, Y Elkrim, ... Cancer research 76 (1), 35-42, 2016 | 236 | 2016 |
Functional relationship between tumor-associated macrophages and macrophage colony-stimulating factor as contributors to cancer progression D Laoui, E Van Overmeire, P De Baetselier, JA Van Ginderachter, G Raes Frontiers in immunology 5, 113383, 2014 | 230 | 2014 |
Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues E Van Overmeire, D Laoui, J Keirsse, JA Van Ginderachter, A Sarukhan Frontiers in immunology 5, 82149, 2014 | 190 | 2014 |
Tissue-resident versus monocyte-derived macrophages in the tumor microenvironment Q Lahmar, J Keirsse, D Laoui, K Movahedi, E Van Overmeire, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1865 (1), 23-34, 2016 | 164 | 2016 |
PET imaging of macrophage mannose receptor–expressing macrophages in tumor stroma using 18F-radiolabeled camelid single-domain antibody fragments A Blykers, S Schoonooghe, C Xavier, K D’hoe, D Laoui, M D’Huyvetter, ... Journal of Nuclear Medicine 56 (8), 1265-1271, 2015 | 147 | 2015 |
Myeloid cell heterogeneity in cancer: not a single cell alike M Kiss, S Van Gassen, K Movahedi, Y Saeys, D Laoui Cellular immunology 330, 188-201, 2018 | 138 | 2018 |
Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site D Laoui, E Van Overmeire, K Movahedi, J Van den Bossche, E Schouppe, ... Immunobiology 216 (11), 1192-1202, 2011 | 121 | 2011 |
Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy H Van Damme, B Dombrecht, M Kiss, H Roose, E Allen, E Van Overmeire, ... Journal for immunotherapy of cancer 9 (2), 2021 | 108 | 2021 |
Systemic reprogramming of monocytes in cancer M Kiss, AA Caro, G Raes, D Laoui Frontiers in oncology 10, 1399, 2020 | 98 | 2020 |