Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family X De Deken, D Wang, MC Many, S Costagliola, F Libert, G Vassart, ... Journal of Biological Chemistry 275 (30), 23227-23233, 2000 | 782 | 2000 |
Roles of hydrogen peroxide in thyroid physiology and disease Y Song, N Driessens, M Costa, X De Deken, V Detours, B Corvilain, ... The Journal of Clinical Endocrinology & Metabolism 92 (10), 3764-3773, 2007 | 283 | 2007 |
Candida albicans zinc cluster protein Upc2p confers resistance to antifungal drugs and is an activator of ergosterol biosynthetic genes S MacPherson, B Akache, S Weber, X De Deken, M Raymond, B Turcotte Antimicrobial agents and chemotherapy 49 (5), 1745-1752, 2005 | 267 | 2005 |
Activation of Dual Oxidases Duox1 and Duox2 DIFFERENTIAL REGULATION MEDIATED BY cAMP-DEPENDENT PROTEIN KINASE AND PROTEIN KINASE C-DEPENDENT PHOSPHORYLATION S Rigutto, C Hoste, H Grasberger, M Milenkovic, D Communi, JE Dumont, ... Journal of Biological Chemistry 284 (11), 6725-6734, 2009 | 245 | 2009 |
Characterization of ThOX Proteins as Components of the Thyroid H2O2-Generating System X De Deken, D Wang, JE Dumont, F Miot Experimental cell research 273 (2), 187-196, 2002 | 243 | 2002 |
Hydrogen peroxide induces DNA single-and double-strand breaks in thyroid cells and is therefore a potential mutagen for this organ N Driessens, S Versteyhe, C Ghaddhab, A Burniat, X De Deken, ... Endocrine-related cancer 16 (3), 845-856, 2009 | 237 | 2009 |
Genomewide Location Analysis of Candida albicans Upc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance S Znaidi, S Weber, O Zin Al-Abdin, P Bomme, S Saidane, S Drouin, ... Eukaryotic cell 7 (5), 836-847, 2008 | 150 | 2008 |
The nonphagocytic NADPH oxidase Duox1 mediates a positive feedback loop during T cell receptor signaling J Kwon, KE Shatynski, H Chen, S Morand, X De Deken, F Miot, TL Leto, ... Science signaling 3 (133), ra59-ra59, 2010 | 141 | 2010 |
Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling X De Deken, B Corvilain, JE Dumont, F Miot Antioxidants & redox signaling 20 (17), 2776-2793, 2014 | 134 | 2014 |
NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation R Ameziane-El-Hassani, M Talbot, MC de Souza Dos Santos, ... Proceedings of the National Academy of Sciences 112 (16), 5051–5056, 2015 | 132 | 2015 |
The zinc cluster transcription factor Tac1p regulates PDR16 expression in Candida albicans S Znaidi, X De Deken, S Weber, T Rigby, A Nantel, M Raymond Molecular microbiology 66 (2), 440-452, 2007 | 112 | 2007 |
Identification of a Novel Partner of Duox EFP1, A THIOREDOXIN-RELATED PROTEIN D Wang, X De Deken, M Milenkovic, Y Song, I Pirson, JE Dumont, F Miot Journal of Biological Chemistry 280 (4), 3096-3103, 2005 | 111 | 2005 |
Urothelial cells produce hydrogen peroxide through the activation of Duox1 Á Donkó, É Ruisanchez, A Orient, B Enyedi, R Kapui, Z Péterfi, ... Free Radical Biology and Medicine 49 (12), 2040-2048, 2010 | 103 | 2010 |
Cancer heterogeneity is not compatible with one unique cancer cell metabolic map A Strickaert, M Saiselet, G Dom, X De Deken, JE Dumont, O Feron, ... Oncogene 36 (19), 2637, 2017 | 97 | 2017 |
Mice deficient in dual oxidase maturation factors are severely hypothyroid H Grasberger, X De Deken, OB Mayo, H Raad, M Weiss, XH Liao, ... Molecular endocrinology 26 (3), 481-492, 2012 | 96 | 2012 |
Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor H Grasberger, X De Deken, F Miot, J Pohlenz, S Refetoff Molecular Endocrinology 21 (6), 1408-1421, 2007 | 96 | 2007 |
Association of duoxes with thyroid peroxidase and its regulation in thyrocytes Y Song, J Ruf, P Lothaire, D Dequanter, G Andry, E Willemse, JE Dumont, ... The Journal of Clinical Endocrinology & Metabolism 95 (1), 375-382, 2010 | 95 | 2010 |
IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response K Fink, L Martin, E Mukawera, S Chartier, X De Deken, E Brochiero, F Miot, ... Cell research 23 (5), 673-690, 2013 | 87 | 2013 |
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult M Milenkovic, X De Deken, L Jin, M De Felice, R Di Lauro, JE Dumont, ... Journal of endocrinology 192 (3), 615-626, 2007 | 83 | 2007 |
Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2‐generating enzyme DUOX2 associated with … C Hoste, S Rigutto, G Van Vliet, F Miot, X De Deken Human mutation 31 (4), E1304-E1319, 2010 | 77 | 2010 |