Design and optimization of aspartate N-acetyltransferase inhibitors for the potential treatment of Canavan disease B Thangavelu, V Mutthamsetty, Q Wang, RE Viola Bioorganic & medicinal chemistry 25 (3), 870-885, 2017 | 18 | 2017 |
Development of bisubstrate analog inhibitors of aspartate N‐acetyltransferase, a critical brain enzyme V Mutthamsetty, GP Dahal, Q Wang, RE Viola Chemical Biology & Drug Design 95 (1), 48-57, 2020 | 5 | 2020 |
Potent phthalate inhibitors of aspartate N-acetyltransferase and selective aspartate pathway inhibitors RE Viola, B Thangavelu, V Mutthamsetty, Q Wang, P Bhansali US Patent 10,449,168, 2019 | 1 | 2019 |
Potent inhibitors of aspartate N-acetyl-transferase for the treatment of Canavan disease RE Viola, B Thangavelu, V Mutthamsetty, Q Wang US Patent 11,186,541, 2021 | | 2021 |
Development of amino acid-based inhibitors against Aspartate-N-Acetyltransferase (ANAT) for the treatment of Canavan disease V Mutthamsetty, B Thangavelu, Q Wang, R Viola ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Aspartate N‐acetyltransferase: a key enzyme in neurobiology and cancer Q Wang, M Zhao, GG Parungao, B Thangavelu, V Mutthamsetty, RE Viola The FASEB Journal 31, 921.21-921.21, 2017 | | 2017 |
Design and Synthesis of Amino Acid-based Inhibitors Against Key Enzymes V Mutthamsetty University of Toledo, 2017 | | 2017 |
Substrate reduction therapy for Canavan disease Q Wang, M Zhao, G Parungao, B Thangavelu, V Mutthamsetty, R Viola ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
Design and synthesis of inhibitors against aspartate-N-acetyl transferase (ANAT)-A novel approach to treat Canavan disease V Mutthamsetty, B Thangavelu, Q Wang, R Viola ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |