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Kyle Roskamp
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Stability of protein-specific hydration shell on crowding
KY Huang, CN Kingsley, R Sheil, CY Cheng, JC Bierma, KW Roskamp, ...
Journal of the American Chemical Society 138 (16), 5392-5402, 2016
332016
Structural basis for shelterin bridge assembly
JK Kim, J Liu, X Hu, C Yu, K Roskamp, B Sankaran, L Huang, EA Komives, ...
Molecular cell 68 (4), 698-714. e5, 2017
302017
Protein refractive index increment is determined by conformation as well as composition
D Khago, JC Bierma, KW Roskamp, N Kozlyuk, RW Martin
Journal of Physics: Condensed Matter 30 (43), 435101, 2018
252018
Sequence comparison, molecular modeling, and network analysis predict structural diversity in cysteine proteases from the Cape sundew, Drosera capensis
CT Butts, X Zhang, JE Kelly, KW Roskamp, MH Unhelkar, JA Freites, ...
Computational and structural biotechnology journal 14, 271-282, 2016
182016
Multiple aggregation pathways in human γS-crystallin and its aggregation-prone G18V variant
KW Roskamp, DM Montelongo, CD Anorma, DN Bandak, JA Chua, ...
Investigative ophthalmology & visual science 58 (4), 2397-2405, 2017
172017
Human γS-crystallin–copper binding helps buffer against aggregation caused by oxidative damage
KW Roskamp, S Azim, G Kassier, B Norton-Baker, MA Sprague-Piercy, ...
Biochemistry 59 (25), 2371-2385, 2020
132020
Divalent Cations and the Divergence of βγ-Crystallin Function
KW Roskamp, N Kozlyuk, S Sengupta, JC Bierma, RW Martin
Biochemistry 58 (45), 4505-4518, 2019
132019
Function and aggregation in structural eye lens crystallins
KW Roskamp, CN Paulson, WD Brubaker, RW Martin
Accounts of chemical research 53 (4), 863-874, 2020
102020
Chemical Properties Determine Solubility and Stability in βγ‐Crystallins of the Eye Lens
MA Rocha, MA Sprague‐Piercy, AO Kwok, KW Roskamp, RW Martin
ChemBioChem 22 (8), 1329-1346, 2021
92021
Human αB-crystallin discriminates between aggregation-prone and function-preserving variants of a client protein
MA Sprague-Piercy, E Wong, KW Roskamp, JN Fakhoury, JA Freites, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (3), 129502, 2020
92020
Controlling liquid–liquid phase separation of cold-adapted crystallin proteins from the Antarctic toothfish
JC Bierma, KW Roskamp, AP Ledray, AJ Kiss, CHC Cheng, RW Martin
Journal of molecular biology 430 (24), 5151-5168, 2018
92018
Deamidation of the human eye lens protein γS-crystallin accelerates oxidative aging
B Norton-Baker, P Mehrabi, AO Kwok, KW Roskamp, MA Rocha, ...
Structure 30 (5), 763-776. e4, 2022
12022
Accelerated oxidative aging in deamidated variants of the human eye lens protein γ (S)-crystallin
B Norton-Baker, P Mehrabi, A Kwok, K Roskamp, M Sprague-Piercy, ...
Biophysical Journal 121 (3), 22a, 2022
2022
Identifying the Structural Features that Differentiate Client Proteins of αB-Crystallin
M Sprauge-Piercy, K Roskamp, RW Martin
Biophysical Journal 118 (3), 511a, 2020
2020
Aggregation of Gamma S-Crystallin Mediated by UV Light and Divalent Metal Cations
K Roskamp, B Norton-Baker, N Kozlyuk, J Bierma, S Sengupta, ...
Biophysical Journal 118 (3), 336a, 2020
2020
Controlling liquid-liquid phase separation of Antartic toothfish crystallins through surface residue mutations
J Bierma, K Roskamp, A Ledray, A Kiss, CHC Cheng, R Martin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Growth mechanisms and catalytic efficiency in metal-organic framework (MOF) composites containing enzymes and structural proteins
B Carpenter, A Ogata, K Roskamp, R Martin, J Patterson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
2019
Uncovering the Role of Surface Residues and Buffer Composition in Liquid-Liquid Phase Separation of Eye Lens Crystallins from an Antarctic Toothfish
JC Bierma, K Roskamp, A Ledray, AJ Kiss, CHC Cheng, RW Martin
Biophysical Journal 116 (3), 454a, 2019
2019
Investigation of Gamma-Crystallin Biophysical Properties and Aggregation Pathways Relevant to Cataract Formation
K Roskamp
University of California, Irvine, 2019
2019
Exploration of the N-terminal extension's role in human gamma-S crystallin function
K Roskamp, A Chenault, R Martin
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
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Articles 1–20