Nahum Sonenberg
Nahum Sonenberg
James McGill Professor
Verified email at mcgill.ca - Homepage
TitleCited byYear
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
W Filipowicz, SN Bhattacharyya, N Sonenberg
Nature reviews genetics 9 (2), 102-114, 2008
49262008
Upstream and downstream of mTOR
N Hay, N Sonenberg
Genes & development 18 (16), 1926-1945, 2004
42962004
Regulation of translation initiation in eukaryotes: mechanisms and biological targets
N Sonenberg, AG Hinnebusch
Cell 136 (4), 731-745, 2009
24212009
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
AC Gingras, B Raught, N Sonenberg
Annual review of biochemistry 68 (1), 913-963, 1999
22971999
Regulation of mRNA translation and stability by microRNAs
MR Fabian, N Sonenberg, W Filipowicz
Annual review of biochemistry 79, 351-379, 2010
22362010
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
J Pelletier, N Sonenberg
Nature 334 (6180), 320-325, 1988
20851988
Regulation of translation initiation by FRAP/mTOR
AC Gingras, B Raught, N Sonenberg
Genes & development 15 (7), 807-826, 2001
15082001
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
A Pause, GJ Belsham, AC Gingras, O Donzé, TA Lin, JC Lawrence, ...
Nature 371 (6500), 762-767, 1994
13091994
Translational control in stress and apoptosis
M Holcik, N Sonenberg
Nature reviews Molecular cell biology 6 (4), 318-327, 2005
13042005
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ...
Genes & development 13 (11), 1422-1437, 1999
11991999
Metformin is an AMP kinase–dependent growth inhibitor for breast cancer cells
M Zakikhani, R Dowling, IG Fantus, N Sonenberg, M Pollak
Cancer research 66 (21), 10269-10273, 2006
10672006
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5'cap
A Lazaris-Karatzas, KS Montine, N Sonenberg
Nature 345 (6275), 544-547, 1990
10191990
Regulation of cap-dependent translation by eIF4E inhibitory proteins
JD Richter, N Sonenberg
Nature 433 (7025), 477-480, 2005
9702005
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway
AC Gingras, SG Kennedy, MA O’Leary, N Sonenberg, N Hay
Genes & development 12 (4), 502-513, 1998
9571998
The mRNA 5′ cap-binding protein eIF4E and control of cell growth
N Sonenberg, AC Gingras
Current opinion in cell biology 10 (2), 268-275, 1998
8841998
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
AC Gingras, B Raught, SP Gygi, A Niedzwiecka, M Miron, SK Burley, ...
Genes & development 15 (21), 2852-2864, 2001
8712001
Metformin inhibits mammalian target of rapamycin–dependent translation initiation in breast cancer cells
RJO Dowling, M Zakikhani, IG Fantus, M Pollak, N Sonenberg
Cancer research 67 (22), 10804-10812, 2007
8612007
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ...
Immunity 21 (1), 81-93, 2004
8592004
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
DF Stojdl, B Lichty, S Knowles, R Marius, H Atkins, N Sonenberg, JC Bell
Nature medicine 6 (7), 821-825, 2000
8532000
Rapamycin blocks the phosphorylation of 4E‐BP1 and inhibits cap‐dependent initiation of translation.
L Beretta, AC Gingras, YV Svitkin, MN Hall, N Sonenberg
The EMBO journal 15 (3), 658-664, 1996
7571996
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Articles 1–20