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Prof David Kavanagh
Prof David Kavanagh
Professor of Complement Therapeutics, National Renal Complement Therapeutics Centre
Verified email at ncl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome
J Caprioli, M Noris, S Brioschi, G Pianetti, F Castelletti, P Bettinaglio, ...
Blood 108 (4), 1267-1279, 2006
8812006
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes”(KDIGO) Controversies Conference
THJ Goodship, HT Cook, F Fakhouri, FC Fervenza, V Frémeaux-Bacchi, ...
Kidney international 91 (3), 539-551, 2017
6452017
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
JM Seddon, Y Yu, EC Miller, R Reynolds, PL Tan, S Gowrisankar, ...
Nature genetics 45 (11), 1366-1370, 2013
4862013
C-terminal truncations in human 3′-5′ DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy
A Richards, AMJM Van Den Maagdenberg, JC Jen, D Kavanagh, ...
Nature genetics 39 (9), 1068-1070, 2007
4352007
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical …
I Moore, L Strain, I Pappworth, D Kavanagh, PN Barlow, AP Herbert, ...
Blood, The Journal of the American Society of Hematology 115 (2), 379-387, 2010
4012010
Atypical hemolytic uremic syndrome
D Kavanagh, TH Goodship, A Richards
Seminars in nephrology 33 (6), 508-530, 2013
3562013
Thrombotic microangiopathy and the kidney
V Brocklebank, KM Wood, D Kavanagh
Clinical Journal of the American Society of Nephrology 13 (2), 300-317, 2018
3452018
Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort
JE Salmon, C Heuser, M Triebwasser, MK Liszewski, D Kavanagh, ...
PLoS medicine 8 (3), e1001013, 2011
3322011
Atypical aHUS: state of the art
CM Nester, T Barbour, SR de Cordoba, MA Dragon-Durey, ...
Molecular immunology 67 (1), 31-42, 2015
3112015
Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome
D Kavanagh, EJ Kemp, E Mayland, RJ Winney, JS Duffield, G Warwick, ...
Journal of the American Society of Nephrology 16 (7), 2150-2155, 2005
3002005
C3 glomerulopathy—understanding a rare complement-driven renal disease
RJH Smith, GB Appel, AM Blom, HT Cook, VD D’Agati, F Fakhouri, ...
Nature reviews nephrology 15 (3), 129-143, 2019
2902019
Structural basis for sialic acid–mediated self-recognition by complement factor H
BS Blaum, JP Hannan, AP Herbert, D Kavanagh, D Uhrín, T Stehle
Nature chemical biology 11 (1), 77-82, 2015
2812015
Structural basis for engagement by complement factor H of C3b on a self surface
HP Morgan, CQ Schmidt, M Guariento, BS Blaum, D Gillespie, AP Herbert, ...
Nature structural & molecular biology 18 (4), 463-470, 2011
2772011
Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome
EA Moulton, D Kavanagh, J Blouin, A Caudy, N Arzouk, R Cleper, ...
Journal of the American Society of Nephrology 17 (7), 2017-2025, 2006
2762006
A new map of glycosaminoglycan and C3b binding sites on factor H
CQ Schmidt, AP Herbert, D Kavanagh, C Gandy, CJ Fenton, BS Blaum, ...
The Journal of Immunology 181 (4), 2610-2619, 2008
2642008
Extended haplotypes in the complement factor H (CFH) and CFH‐related (CFHR) family of genes protect against age‐related macular degeneration …
GS Hageman, LS Hancox, AJ Taiber, KM Gehrs, DH Anderson, ...
Annals of medicine 38 (8), 592-604, 2006
2632006
Peritoneal dialysis-associated peritonitis in Scotland (1999–2002)
D Kavanagh, GJ Prescott, RA Mactier
Nephrology Dialysis Transplantation 19 (10), 2584-2591, 2004
2372004
Genetics and complement in atypical HUS
D Kavanagh, T Goodship
Pediatric nephrology 25, 2431-2442, 2010
2082010
Hemolytic uremic syndrome in pregnancy and postpartum
A Bruel, D Kavanagh, M Noris, Y Delmas, EKS Wong, E Bresin, F Provôt, ...
Clinical Journal of the American Society of Nephrology 12 (8), 1237-1247, 2017
2062017
The binding of factor H to a complex of physiological polyanions and C3b on cells is impaired in atypical hemolytic uremic syndrome
VP Ferreira, AP Herbert, C Cortés, KA McKee, BS Blaum, ST Esswein, ...
The Journal of Immunology 182 (11), 7009-7018, 2009
2052009
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