Inflammatory signalling in atrial cardiomyocytes: a novel unifying principle in atrial fibrillation pathophysiology D Dobrev, J Heijman, R Hiram, N Li, S Nattel Nature Reviews Cardiology 20 (3), 145-167, 2023 | 112 | 2023 |
Right atrial mechanisms of atrial fibrillation in a rat model of right heart disease R Hiram, P Naud, F Xiong, D Al-u’datt, V Algalarrondo, MG Sirois, ... Journal of the American College of Cardiology 74 (10), 1332-1347, 2019 | 103 | 2019 |
Docosapentaenoic acid monoacylglyceride reduces inflammation and vascular remodeling in experimental pulmonary hypertension C Morin, R Hiram, E Rousseau, PU Blier, S Fortin American Journal of Physiology-Heart and Circulatory Physiology 307 (4 …, 2014 | 66 | 2014 |
Resolvin E1 normalizes contractility, Ca2+ sensitivity and smooth muscle cell migration rate in TNF-α- and IL-6-pretreated human pulmonary arteries R Hiram, E Rizcallah, S Marouan, C Sirois, M Sirois, C Morin, S Fortin, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (8 …, 2015 | 56 | 2015 |
The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease R Hiram, F Xiong, P Naud, J Xiao, M Sirois, JF Tanguay, JC Tardif, ... Cardiovascular Research 117 (7), 1776-1789, 2021 | 51 | 2021 |
Resolvin D1 reverses reactivity and Ca2+ sensitivity induced by ET-1, TNF-α, and IL-6 in the human pulmonary artery R Hiram, E Rizcallah, C Sirois, M Sirois, C Morin, S Fortin, E Rousseau American Journal of Physiology-Heart and Circulatory Physiology 307 (11 …, 2014 | 42 | 2014 |
Role of atrial arrhythmia and ventricular response in atrial fibrillation induced atrial remodelling JB Guichard, F Xiong, XY Qi, N L’Heureux, R Hiram, J Xiao, P Naud, ... Cardiovascular research 117 (2), 462-471, 2021 | 27 | 2021 |
Comparison of atrial remodeling caused by sustained atrial flutter versus atrial fibrillation JB Guichard, P Naud, F Xiong, X Qi, N L’heureux, R Hiram, JC Tardif, ... Journal of the American College of Cardiology 76 (4), 374-388, 2020 | 27 | 2020 |
Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling J Wu, T Liu, S Shi, Z Fan, R Hiram, F Xiong, B Cui, X Su, R Chang, ... Cardiovascular Diabetology 21 (1), 197, 2022 | 25 | 2022 |
Pulmonary disease, pulmonary hypertension and atrial fibrillation R Hiram, S Provencher Cardiac Electrophysiology Clinics 13 (1), 141-153, 2021 | 23 | 2021 |
Mechanisms and management of thyroid disease and atrial fibrillation: impact of atrial electrical remodeling and cardiac fibrosis A Takawale, M Aguilar, Y Bouchrit, R Hiram Cells 11 (24), 4047, 2022 | 21 | 2022 |
Current knowledge into the role of the peptidylarginine deiminase (PAD) enzyme family in cardiovascular disease GFA Doa'a, BG Allen, R Hiram, N Alrabadi European Journal of Pharmacology 891, 173765, 2021 | 17 | 2021 |
Resolution-promoting autacoids demonstrate promising cardioprotective effects against heart diseases R Hiram Molecular biology reports 49 (6), 5179-5197, 2022 | 14 | 2022 |
Implications of enigmatic transglutaminase 2 (TG2) in cardiac diseases and therapeutic developments GFA Doa'a, CC Tranchant, A Al-Dwairi, M Alqudah, O Al-Shboul, R Hiram, ... Biochemical Pharmacology 201, 115104, 2022 | 12 | 2022 |
Cardiac cytokine therapy? Relevance of targeting inflammatory mediators to combat cardiac arrhythmogenic remodeling R Hiram International Journal of cardiology. Heart & Vasculature 37, 2021 | 9 | 2021 |
An inflammation resolution–promoting intervention prevents atrial fibrillation caused by left ventricular dysfunction R Hiram, F Xiong, P Naud, J Xiao, DK Sosnowski, E Le Quilliec, A Saljic, ... Cardiovascular Research 120 (4), 345-359, 2024 | 8 | 2024 |
Evidence of failed resolution mechanisms in arrhythmogenic inflammation, fibrosis and right heart disease R Younes, CA LeBlanc, R Hiram Biomolecules 12 (5), 720, 2022 | 8 | 2022 |
MAG‐DPA curbs inflammatory biomarkers and pharmacological reactivity in cytokine‐triggered hyperresponsive airway models R Khaddaj‐Mallat, R Hiram, C Sirois, M Sirois, E Rizcallah, S Marouan, ... Pharmacology Research & Perspectives 4 (6), e00263, 2016 | 6 | 2016 |
Involvement and possible role of transglutaminases 1 and 2 in mediating fibrotic signalling, collagen cross-linking and cell proliferation in neonatal rat ventricular fibroblasts DGF Al-U’datt, CC Tranchant, B Al-Husein, R Hiram, A Al-Dwairi, ... PLoS One 18 (2), e0281320, 2023 | 5 | 2023 |
Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats GFA Doa'a, CC Tranchant, M Alu'datt, S Abusara, A Al-Dwairi, M AlQudah, ... Life Sciences 321, 121564, 2023 | 4 | 2023 |