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Doug Crump
Doug Crump
Environment and Climate Change Canada
Verified email at ec.gc.ca
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Cited by
Year
Adverse outcome pathway (AOP) development I: strategies and principles
DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ...
Toxicological Sciences 142 (2), 312-320, 2014
6222014
Adverse outcome pathway development II: best practices
DL Villeneuve, D Crump, N Garcia-Reyero, M Hecker, TH Hutchinson, ...
Toxicological Sciences 142 (2), 321-330, 2014
2452014
In Ovo Effects of Two Organophosphate Flame Retardants—TCPP and TDCPP—on Pipping Success, Development, mRNA Expression, and Thyroid Hormone …
A Farhat, D Crump, S Chiu, KL Williams, RJ Letcher, LT Gauthier, ...
toxicological sciences 134 (1), 92-102, 2013
2222013
Rapid in vitro metabolism of the flame retardant triphenyl phosphate and effects on cytotoxicity and mRNA expression in chicken embryonic hepatocytes
G Su, D Crump, RJ Letcher, SW Kennedy
Environmental science & technology 48 (22), 13511-13519, 2014
2002014
Exposure to the herbicide acetochlor alters thyroid hormone-dependent gene expression and metamorphosis in Xenopus Laevis.
D Crump, K Werry, N Veldhoen, G Van Aggelen, CC Helbing
Environmental Health Perspectives 110 (12), 1199-1205, 2002
1992002
The role of amino acid neurotransmitters in the regulation of pituitary gonadotropin release in fish
VL Trudeau, D Spanswick, EJ Fraser, K Lariviere, D Crump, S Chiu, ...
Biochemistry and Cell Biology 78 (3), 241-259, 2000
1532000
Effects of tris (1, 3-dichloro-2-propyl) phosphate and tris (1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal …
D Crump, S Chiu, SW Kennedy
Toxicological Sciences 126 (1), 140-148, 2012
1402012
Amino acid sequence of the ligand-binding domain of the aryl hydrocarbon receptor 1 predicts sensitivity of wild birds to effects of dioxin-like compounds
R Farmahin, GE Manning, D Crump, D Wu, LJ Mundy, SP Jones, ...
Toxicological Sciences 131 (1), 139-152, 2013
1232013
Use of an avian hepatocyte assay and the avian toxchip polymerse chain reaction array for testing prioritization of 16 organic flame retardants
E Porter, D Crump, C Egloff, S Chiu, SW Kennedy
Environmental toxicology and chemistry 33 (3), 573-582, 2014
1012014
Persistent, bioaccumulative, and toxic properties of liquid crystal monomers and their detection in indoor residential dust
H Su, S Shi, M Zhu, D Crump, RJ Letcher, JP Giesy, G Su
Proceedings of the National Academy of Sciences 116 (52), 26450-26458, 2019
942019
In Vitro Metabolism of the Flame Retardant Triphenyl Phosphate in Chicken Embryonic Hepatocytes and the Importance of the Hydroxylation Pathway
G Su, RJ Letcher, D Crump, DM Gooden, HM Stapleton
Environmental Science & Technology Letters 2 (4), 100-104, 2015
942015
Tris (1, 3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos
A Farhat, JK Buick, A Williams, CL Yauk, JM O'Brien, D Crump, ...
Toxicology and applied pharmacology 275 (2), 104-112, 2014
912014
In vitro and in ovo effects of four brominated flame retardants on toxicity and hepatic mRNA expression in chicken embryos
C Egloff, D Crump, S Chiu, G Manning, KK McLaren, CG Cassone, ...
Toxicology letters 207 (1), 25-33, 2011
822011
Expression Profiles of Novel Thyroid Hormone-Responsive Genes and Proteins in the Tail of Xenopus laevis Tadpoles Undergoing Precocious Metamorphosis
CC Helbing, K Werry, D Crump, D Domanski, N Veldhoen, CM Bailey
Molecular Endocrinology 17 (7), 1395-1409, 2003
762003
Sequence and in vitro function of chicken, ring-necked pheasant, and Japanese quail AHR1 predict in vivo sensitivity to dioxins
R Farmahin, D Wu, D Crump, JC Hervé, SP Jones, ME Hahn, SI Karchner, ...
Environmental science & technology 46 (5), 2967-2975, 2012
752012
In Ovo Effects of Perfluorohexane Sulfonate and Perfluorohexanoate on Pipping Success, Development, mRNA Expression, and Thyroid Hormone Levels in …
CG Cassone, V Vongphachan, S Chiu, KL Williams, RJ Letcher, ...
Toxicological Sciences 127 (1), 216-224, 2012
742012
Organophosphate ester, 2-ethylhexyl diphenyl phosphate (EHDPP), elicits cytotoxic and transcriptomic effects in chicken embryonic hepatocytes and its biotransformation profile …
J Shen, Y Zhang, N Yu, D Crump, J Li, H Su, RJ Letcher, G Su
Environmental science & technology 53 (4), 2151-2160, 2019
702019
The effects of Dechlorane Plus on toxicity and mRNA expression in chicken embryos: a comparison of in vitro and in ovo approaches
D Crump, S Chiu, LT Gauthier, NJ Hickey, RJ Letcher, SW Kennedy
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2011
602011
Cytochrome P4501A Induction by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Two Chlorinated Dibenzofurans in Primary Hepatocyte Cultures of Three Avian Species
JC Hervé, D Crump, SP Jones, LJ Mundy, JP Giesy, MJ Zwiernik, ...
Toxicological sciences 113 (2), 380-391, 2010
552010
Tris (2-butoxyethyl) phosphate and triethyl phosphate alter embryonic development, hepatic mRNA expression, thyroid hormone levels, and circulating bile acid concentrations in …
C Egloff, D Crump, E Porter, KL Williams, RJ Letcher, LT Gauthier, ...
Toxicology and applied pharmacology 279 (3), 303-310, 2014
542014
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