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Gabriel Fenteany
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Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
G Fenteany, RF Standaert, WS Lane, S Choi, EJ Corey, SL Schreiber
Science 268 (5211), 726-731, 1995
20081995
Lactacystin, proteasome function, and cell fate
G Fenteany, SL Schreiber
Journal of Biological Chemistry 273 (15), 8545-8548, 1998
5171998
Lactacystin and clasto-lactacystin β-lactone modify multiple proteasome β-subunits and inhibit intracellular protein degradation and major histocompatibility complex class I …
A Craiu, M Gaczynska, T Akopian, CF Gramm, G Fenteany, AL Goldberg, ...
Journal of Biological Chemistry 272 (20), 13437-13445, 1997
5121997
Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement
R Farooqui, G Fenteany
Journal of cell science 118 (1), 51-63, 2005
5072005
Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets
G Fenteany, PA Janmey, TP Stossel
Current biology 10 (14), 831-838, 2000
3702000
A beta-lactone related to lactacystin induces neurite outgrowth in a neuroblastoma cell line and inhibits cell cycle progression in an osteosarcoma cell line.
G Fenteany, RF Standaert, GA Reichard, EJ Corey, SL Schreiber
Proceedings of the National Academy of Sciences 91 (8), 3358-3362, 1994
2971994
Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer
G Ren, S Baritaki, H Marathe, J Feng, S Park, S Beach, PS Bazeley, ...
Cancer research 72 (12), 3091-3104, 2012
2602012
Small-molecule inhibitors of actin dynamics and cell motility
G Fenteany, S Zhu
Current topics in medicinal chemistry 3 (6), 593-616, 2003
2562003
A chemical inhibitor reveals the role of Raf kinase inhibitor protein in cell migration
S Zhu, KT Mc Henry, WS Lane, G Fenteany
Chemistry & biology 12 (9), 981-991, 2005
1312005
Cytoskeletal remodeling in leukocyte function
G Fenteany, M Glogauer
Current opinion in hematology 11 (1), 15-24, 2004
1242004
Raf kinase inhibitor protein suppresses nuclear factor-κB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression
AB Beshir, G Ren, AN Magpusao, LM Barone, KC Yeung, G Fenteany
Cancer letters 299 (2), 137-149, 2010
1062010
Cell surface actin remodeling
TP Stossel, G Fenteany, JH Hartwig
Journal of cell science 119 (16), 3261-3264, 2006
882006
Lactacystin analogs
G Fenteany, TF Jamison, SL Schreiber, RF Standaert
US Patent 5,756,764, 1998
821998
Synthesis and structure–activity relationships of metal–ligand complexes that potently inhibit cell migration
AB Beshir, SK Guchhait, JA Gascón, G Fenteany
Bioorganic & medicinal chemistry letters 18 (2), 498-504, 2008
712008
A non‐antibacterial oxazolidinone derivative that inhibits epithelial cell sheet migration
KT Mc Henry, SV Ankala, AK Ghosh, G Fenteany
ChemBioChem 3 (11), 1105-1111, 2002
702002
The structural requirements for inhibition of proteasome function by the lactacystin-derived β-lactone and synthetic analogs
EJ Corey, WDZ Li, T Nagamitsu, G Fenteany
Tetrahedron 55 (11), 3305-3316, 1999
701999
Cucurbitacin I inhibits cell motility by indirectly interfering with actin dynamics
DA Knecht, RA LaFleur, AW Kahsai, CE Argueta, AB Beshir, G Fenteany
PLoS One 5 (11), e14039, 2010
612010
Diversity through a branched reaction pathway: Generation of multicyclic scaffolds and identification of antimigratory agents
Z Wang, S Castellano, SS Kinderman, CE Argueta, AB Beshir, ...
Chemistry–A European Journal 17 (2), 649-654, 2011
592011
Glycogen synthase kinase-3 acts upstream of ADP-ribosylation factor 6 and Rac1 to regulate epithelial cell migration
R Farooqui, S Zhu, G Fenteany
Experimental cell research 312 (9), 1514-1525, 2006
592006
Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44
AW Kahsai, S Zhu, DJ Wardrop, WS Lane, G Fenteany
Chemistry & biology 13 (9), 973-983, 2006
572006
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