Jerome Kluza
Jerome Kluza
INSERM UMR9020 – UMR-S 1277 - Canther – Cancer Heterogeneity, Plasticity and Resistance to Therapies
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Targeting chelatable iron as a therapeutic modality in Parkinson's disease
D Devos, C Moreau, JC Devedjian, J Kluza, M Petrault, C Laloux, ...
Antioxidants & redox signaling 21 (2), 195-210, 2014
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells
MS Trabelsi, M Daoudi, J Prawitt, S Ducastel, V Touche, SI Sayin, ...
Nature communications 6 (1), 1-13, 2015
Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells
J Kluza, P Marchetti, MA Gallego, S Lancel, C Fournier, A Loyens, ...
Oncogene 23 (42), 7018-7030, 2004
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D
J Kluza, MA Gallego, A Loyens, JC Beauvillain, JMF Sousa-Faro, ...
Cancer Research 66 (6), 3177-3187, 2006
Ventricular myocyte caspases are directly responsible for endotoxin-induced cardiac dysfunction
S Lancel, O Joulin, R Favory, JF Goossens, J Kluza, C Chopin, ...
Circulation 111 (20), 2596-2604, 2005
Mitochondrial oxidative stress is the Achille's heel of melanoma cells resistant to Braf-mutant inhibitor
P Corazao-Rozas, P Guerreschi, M Jendoubi, F André, A Jonneaux, ...
Oncotarget 4 (11), 1986, 2013
Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants
J Kluza, P Corazao-Rozas, Y Touil, M Jendoubi, C Maire, P Guerreschi, ...
Cancer research 72 (19), 5035-5047, 2012
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux
M Vanhuyse, J Kluza, C Tardy, G Otero, C Cuevas, C Bailly, A Lansiaux
Cancer letters 221 (2), 165-175, 2005
Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D
C Ballot, J Kluza, S Lancel, A Martoriati, SM Hassoun, L Mortier, ...
Apoptosis 15 (7), 769-781, 2010
Mitochondrial electron transport is the cellular target of the oncology drug elesclomol
RK Blackman, K Cheung-Ong, M Gebbia, DA Proia, S He, J Kepros, ...
PloS one 7 (1), e29798, 2012
Lactate inhibits the pro-inflammatory response and metabolic reprogramming in murine macrophages in a GPR81-independent manner
A Errea, D Cayet, P Marchetti, C Tang, J Kluza, S Offermanns, JC Sirard, ...
PloS one 11 (11), e0163694, 2016
Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway
MA Gallego, C Ballot, J Kluza, N Hajji, A Martoriati, L Castera, C Cuevas, ...
Oncogene 27 (14), 1981-1992, 2008
Apoptotic response of HL-60 human leukemia cells to the antitumor drug TAS-103
J Kluza, A Lansiaux, N Wattez, C Mahieu, N Osheroff, C Bailly
Cancer research 60 (15), 4077-4084, 2000
Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78
M Kotecha, J Kluza, G Wells, CC O'Hare, C Forni, R Mantovani, ...
Molecular cancer therapeutics 7 (5), 1319-1328, 2008
Air pollution-derived PM2. 5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells
B Leclercq, J Kluza, S Antherieu, J Sotty, LY Alleman, E Perdrix, A Loyens, ...
Environmental pollution 243, 1434-1449, 2018
Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells
J Kluza, M Jendoubi, C Ballot, A Dammak, A Jonneaux, T Idziorek, S Joha, ...
PLoS One 6 (7), e21924, 2011
Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D
C Ballot, J Kluza, A Martoriati, U Nyman, P Formstecher, B Joseph, ...
Molecular cancer therapeutics 8 (12), 3307-3317, 2009
Relationship between cell cycle changes and variations of the mitochondrial membrane potential induced by etoposide
M Facompré, N Wattez, J Kluza, A Lansiaux, C Bailly
Molecular Cell Biology Research Communications 4 (1), 37-42, 2000
Cytotoxicity and DNA binding properties of the plant alkaloid burasaine
J Kluza, B Baldeyrou, P Colson, P Rasoanaivo, L Mambu, F Frappier, ...
European journal of pharmaceutical sciences 20 (4-5), 383-391, 2003
Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1
J Kluza, A Lansiaux, N Wattez, MP Hildebrand, S Léonce, A Pierré, ...
Biochemical pharmacology 63 (8), 1443-1452, 2002
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