Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13590* | 2021 |
Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms EA Sausville, SG Arbuck, R Messmann, D Headlee, KS Bauer, RM Lush, ... Journal of Clinical Oncology 19 (8), 2319-2333, 2001 | 391 | 2001 |
Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling AD Balgi, BD Fonseca, E Donohue, TCF Tsang, P Lajoie, CG Proud, ... PloS one 4 (9), e7124, 2009 | 381 | 2009 |
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis G Juan, F Traganos, WM James, JM Ray, M Roberge, DM Sauve, ... Cytometry: The Journal of the International Society for Analytical Cytology …, 1998 | 301 | 1998 |
Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites E Gilson, M Roberge, R Giraldo, D Rhodes, SM Gasser Journal of molecular biology 231 (2), 293-310, 1993 | 283 | 1993 |
Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation HJ Anderson, JE Coleman, RJ Andersen, M Roberge Cancer chemotherapy and pharmacology 39, 223-226, 1996 | 208 | 1996 |
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action K Baetz, L McHardy, K Gable, T Tarling, D Rebérioux, J Bryan, ... Proceedings of the National Academy of Sciences 101 (13), 4525-4530, 2004 | 205 | 2004 |
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen S Ramón-García, C Ng, H Anderson, JD Chao, X Zheng, T Pfeifer, ... Antimicrobial agents and chemotherapy 55 (8), 3861-3869, 2011 | 203 | 2011 |
Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 … XW Guo, JP Th'ng, RA Swank, HJ Anderson, C Tudan, EM Bradbury, ... The EMBO journal 14 (5), 976-985, 1995 | 203 | 1995 |
Granulatimide and isogranulatimide, aromatic alkaloids with G2 checkpoint inhibition activity isolated from the Brazilian ascidian Didemnum granulatum: structure elucidation … RGS Berlinck, R Britton, E Piers, L Lim, M Roberge, R Moreira da Rocha, ... The Journal of Organic Chemistry 63 (26), 9850-9856, 1998 | 173 | 1998 |
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling BD Fonseca, GH Diering, MA Bidinosti, K Dalal, T Alain, AD Balgi, ... Journal of Biological Chemistry 287 (21), 17530-17545, 2012 | 170 | 2012 |
Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine D Curman, B Cinel, DE Williams, N Rundle, WD Block, AA Goodarzi, ... Journal of Biological Chemistry 276 (21), 17914-17919, 2001 | 166 | 2001 |
Phosphorylation-induced Rearrangement of the Histone H3 NH2-terminal Domain during Mitotic Chromosome Condensation DM Sauvé, HJ Anderson, JM Ray, WM James, M Roberge The Journal of cell biology 145 (2), 225-235, 1999 | 165 | 1999 |
Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis KKY Lam, X Zheng, R Forestieri, AD Balgi, M Nodwell, S Vollett, ... PLoS pathogens 8 (5), e1002691, 2012 | 164 | 2012 |
High-Throughput Assay for G2 Checkpoint Inhibitors and Identification of the Structurally Novel Compound Isogranulatimide M Roberge, RGS Berlinck, L Xu, HJ Anderson, LY Lim, D Curman, ... Cancer Research 58 (24), 5701-5706, 1998 | 152 | 1998 |
Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts M Roberge, B Cinel, HJ Anderson, L Lim, X Jiang, L Xu, CM Bigg, ... Cancer Research 60 (18), 5052-5058, 2000 | 145 | 2000 |
Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin E Donohue, A Tovey, AW Vogl, S Arns, E Sternberg, RN Young, ... Journal of Biological Chemistry 286 (9), 7290-7300, 2011 | 144 | 2011 |
Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues JA Nieman, JE Coleman, DJ Wallace, E Piers, LY Lim, M Roberge, ... Journal of natural products 66 (2), 183-199, 2003 | 144 | 2003 |
Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A M Roberge, C Tudan, SMF Hung, KW Harder, FR Jirik, H Anderson Cancer research 54 (23), 6115-6121, 1994 | 141 | 1994 |
Spirastrellolide A, An Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea DE Williams, M Roberge, R Van Soest, RJ Andersen Journal of the American Chemical Society 125 (18), 5296-5297, 2003 | 135 | 2003 |