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Michel Roberge
Michel Roberge
Adresse e-mail validée de mail.ubc.ca
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13140*2021
Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms
EA Sausville, SG Arbuck, R Messmann, D Headlee, KS Bauer, RM Lush, ...
Journal of Clinical Oncology 19 (8), 2319-2333, 2001
3912001
Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling
AD Balgi, BD Fonseca, E Donohue, TCF Tsang, P Lajoie, CG Proud, ...
PloS one 4 (9), e7124, 2009
3722009
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis
G Juan, F Traganos, WM James, JM Ray, M Roberge, DM Sauve, ...
Cytometry: The Journal of the International Society for Analytical Cytology …, 1998
2921998
Distortion of the DNA double helix by RAP1 at silencers and multiple telomeric binding sites
E Gilson, M Roberge, R Giraldo, D Rhodes, SM Gasser
Journal of molecular biology 231 (2), 293-310, 1993
2811993
Cytotoxic peptides hemiasterlin, hemiasterlin A and hemiasterlin B induce mitotic arrest and abnormal spindle formation
HJ Anderson, JE Coleman, RJ Andersen, M Roberge
Cancer chemotherapy and pharmacology 39, 223-226, 1996
2021996
Chromosome condensation induced by fostriecin does not require p34cdc2 kinase activity and histone H1 hyperphosphorylation, but is associated with enhanced histone H2A and H3 …
XW Guo, JP Th'ng, RA Swank, HJ Anderson, C Tudan, EM Bradbury, ...
The EMBO journal 14 (5), 976-985, 1995
2021995
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action
K Baetz, L McHardy, K Gable, T Tarling, D Rebérioux, J Bryan, ...
Proceedings of the National Academy of Sciences 101 (13), 4525-4530, 2004
2012004
Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen
S Ramón-García, C Ng, H Anderson, JD Chao, X Zheng, T Pfeifer, ...
Antimicrobial agents and chemotherapy 55 (8), 3861-3869, 2011
1842011
Granulatimide and isogranulatimide, aromatic alkaloids with G2 checkpoint inhibition activity isolated from the Brazilian ascidian Didemnum granulatum: structure elucidation …
RGS Berlinck, R Britton, E Piers, L Lim, M Roberge, R Moreira da Rocha, ...
The Journal of Organic Chemistry 63 (26), 9850-9856, 1998
1681998
Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine
D Curman, B Cinel, DE Williams, N Rundle, WD Block, AA Goodarzi, ...
Journal of Biological Chemistry 276 (21), 17914-17919, 2001
1652001
Phosphorylation-induced Rearrangement of the Histone H3 NH2-terminal Domain during Mitotic Chromosome Condensation
DM Sauvé, HJ Anderson, JM Ray, WM James, M Roberge
The Journal of cell biology 145 (2), 225-235, 1999
1621999
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling
BD Fonseca, GH Diering, MA Bidinosti, K Dalal, T Alain, AD Balgi, ...
Journal of Biological Chemistry 287 (21), 17530-17545, 2012
1612012
Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis
KKY Lam, X Zheng, R Forestieri, AD Balgi, M Nodwell, S Vollett, ...
PLoS pathogens 8 (5), e1002691, 2012
1562012
High-Throughput Assay for G2 Checkpoint Inhibitors and Identification of the Structurally Novel Compound Isogranulatimide
M Roberge, RGS Berlinck, L Xu, HJ Anderson, LY Lim, D Curman, ...
Cancer Research 58 (24), 5701-5706, 1998
1491998
Cell-based screen for antimitotic agents and identification of analogues of rhizoxin, eleutherobin, and paclitaxel in natural extracts
M Roberge, B Cinel, HJ Anderson, L Lim, X Jiang, L Xu, CM Bigg, ...
Cancer Research 60 (18), 5052-5058, 2000
1482000
Antitumor drug fostriecin inhibits the mitotic entry checkpoint and protein phosphatases 1 and 2A
M Roberge, C Tudan, SMF Hung, KW Harder, FR Jirik, H Anderson
Cancer research 54 (23), 6115-6121, 1994
1441994
Inhibition of autophagosome formation by the benzoporphyrin derivative verteporfin
E Donohue, A Tovey, AW Vogl, S Arns, E Sternberg, RN Young, ...
Journal of Biological Chemistry 286 (9), 7290-7300, 2011
1422011
Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues
JA Nieman, JE Coleman, DJ Wallace, E Piers, LY Lim, M Roberge, ...
Journal of natural products 66 (2), 183-199, 2003
1412003
Spirastrellolide A, An Antimitotic Macrolide Isolated from the Caribbean Marine Sponge Spirastrella coccinea
DE Williams, M Roberge, R Van Soest, RJ Andersen
Journal of the American Chemical Society 125 (18), 5296-5297, 2003
1332003
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