Bradley W Doble
Bradley W Doble
Associate Professor, University of Manitoba
Verified email at - Homepage
Cited by
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The ground state of embryonic stem cell self-renewal
QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ...
nature 453 (7194), 519-523, 2008
GSK-3: tricks of the trade for a multi-tasking kinase
BW Doble, JR Woodgett
Journal of cell science 116 (7), 1175-1186, 2003
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
X Zeng, K Tamai, B Doble, S Li, H Huang, R Habas, H Okamura, ...
Nature 438 (7069), 873-877, 2005
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
X Zeng, H Huang, K Tamai, X Zhang, Y Harada, C Yokota, K Almeida, ...
Oxford University Press for The Company of Biologists Limited 135 (2), 367-375, 2008
Phosphorylation by p38 MAPK as an alternative pathway for GSK3β inactivation
TM Thornton, G Pedraza-Alva, B Deng, CD Wood, A Aronshtam, ...
Science 320 (5876), 667-670, 2008
Functional redundancy of GSK-3α and GSK-3β in Wnt/β-catenin signaling shown by using an allelic series of embryonic stem cell lines
BW Doble, S Patel, GA Wood, LK Kockeritz, JR Woodgett
Developmental cell 12 (6), 957-971, 2007
GSK-3 is a master regulator of neural progenitor homeostasis
WY Kim, X Wang, Y Wu, BW Doble, S Patel, JR Woodgett, WD Snider
Nature neuroscience 12 (11), 1390-1397, 2009
Glycogen synthase kinase 3α-specific regulation of murine hepatic glycogen metabolism
K MacAulay, BW Doble, S Patel, T Hansotia, EM Sinclair, DJ Drucker, ...
Cell metabolism 6 (4), 329-337, 2007
Glycogen synthase kinase-3-an overview of an over-achieving protein kinase
L Kockeritz, B Doble, S Patel, JR Woodgett
Current drug targets 7 (11), 1377-1388, 2006
Tissue-specific role of glycogen synthase kinase 3β in glucose homeostasis and insulin action
S Patel, BW Doble, K MacAulay, EM Sinclair, DJ Drucker, JR Woodgett
Molecular and cellular biology 28 (20), 6314-6328, 2008
Deletion of GSK-3β in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation
R Kerkela, L Kockeritz, K MacAulay, J Zhou, BW Doble, C Beahm, ...
The Journal of clinical investigation 118 (11), 3609-3618, 2008
The carboxy-tail of connexin-43 localizes to the nucleus and inhibits cell growth
X Dang, BW Doble, E Kardami
Molecular and cellular biochemistry 242, 35-38, 2003
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
KF Kelly, DY Ng, G Jayakumaran, GA Wood, H Koide, BW Doble
Cell stem cell 8 (2), 214-227, 2011
R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and β-catenin signaling
Q Wei, C Yokota, MV Semenov, B Doble, J Woodgett, X He
Journal of Biological Chemistry 282 (21), 15903-15911, 2007
Prevention of amino acid conversion in SILAC experiments with embryonic stem cells
SC Bendall, C Hughes, MH Stewart, B Doble, M Bhatia, GA Lajoie
Molecular & Cellular Proteomics 7 (9), 1587-1597, 2008
Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?
S Patel, B Doble, JR Woodgett
Biochemical Society Transactions 32 (5), 803-808, 2004
The ε subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation
BW Doble, P Ping, E Kardami
Circulation research 86 (3), 293-301, 2000
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
O Kaidanovich-Beilin, TV Lipina, K Takao, M Van Eede, S Hattori, ...
Molecular brain 2, 1-23, 2009
Role of glycogen synthase kinase-3 in cell fate and epithelial-mesenchymal transitions
BW Doble, JR Woodgett
Cells Tissues Organs 185 (1-3), 73-84, 2007
Nucleotide sequence of katG, encoding catalase HPI of Escherichia coli
BL Triggs-Raine, BW Doble, MR Mulvey, PA Sorby, PC Loewen
Journal of bacteriology 170 (9), 4415-4419, 1988
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