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Hugo Poulin
Hugo Poulin
Centre de Recherche de l'Institut universitaire en santé mentale de Québec
Adresse e-mail validée de crulrg.ulaval.ca
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A recessive Nav1.4 mutation underlies congenital myasthenic syndrome with periodic paralysis
K Habbout, H Poulin, F Rivier, S Giuliano, D Sternberg, B Fontaine, ...
Neurology 86 (2), 161-169, 2016
652016
Fluoxetine blocks Nav1. 5 channels via a mechanism similar to that of class 1 antiarrhythmics
H Poulin, O Theriault, MJ Beaulieu, M Chahine
Biophysical Journal 106 (2), 325a-326a, 2014
422014
Pyridoxal-5′-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors
O Thériault, H Poulin, GR Thomas, AD Friesen, WA Al-Shaqha, ...
Canadian journal of physiology and pharmacology 92 (3), 189-196, 2014
412014
Differential modulation of Nav1. 7 and Nav1. 8 channels by antidepressant drugs
O Thériault, H Poulin, JM Beaulieu, M Chahine
European journal of pharmacology 764, 395-403, 2015
232015
iPSC-derived cardiomyocytes from patients with myotonic dystrophy type 1 have abnormal ion channel functions and slower conduction velocities
H Poulin, A Mercier, M Djemai, V Pouliot, I Deschenes, M Boutjdir, ...
Scientific reports 11 (1), 2500, 2021
202021
Substitutions of the S4DIV R2 residue (R1451) in NaV1.4 lead to complex forms of paramyotonia congenita and periodic paralyses
H Poulin, P Gosselin-Badaroudine, S Vicart, K Habbout, D Sternberg, ...
Scientific reports 8 (1), 2041, 2018
202018
The PLAGL1 gene is down-regulated in human extraskeletal myxoid chondrosarcoma tumors
H Poulin, Y Labelle
Cancer letters 227 (2), 185-191, 2005
202005
Serum-and glucocorticoid-regulated kinase 1 (SGK1) induction by the EWS/NOR1 (NR4A3) fusion protein
H Poulin, C Filion, M Ladanyi, Y Labelle
Biochemical and biophysical research communications 346 (1), 306-313, 2006
142006
NaV1.5 knockout in iPSCs: a novel approach to study NaV1.5 variants in a human cardiomyocyte environment
M Pierre, M Djemai, H Poulin, M Chahine
Scientific reports 11 (1), 17168, 2021
112021
Differentiation of lymphoblastoid-derived iPSCs into functional cardiomyocytes, neurons and myoblasts
H Poulin, L Martineau, V Racine, J Puymirat, M Chahine
Biochemical and biophysical research communications 516 (1), 222-228, 2019
112019
The variant hERG/R148W associated with LQTS is a mutation that reduces current density on co-expression with the WT
A Mechakra, Y Vincent, P Chevalier, G Millat, E Ficker, M Jastrzebski, ...
Gene 536 (2), 348-356, 2014
102014
SCN2A-related epilepsy of infancy with migrating focal seizures: report of a variant with apparent gain- and loss-of-function effects
XR Yang, VKM Ginjupalli, O Theriault, H Poulin, JP Appendino, PYB Au, ...
Journal of Neurophysiology 127 (5), 1388-1397, 2022
82022
R1617Q epilepsy mutation slows NaV1.6 sodium channel inactivation and increases the persistent current and neuronal firing
H Poulin, M Chahine
The Journal of Physiology 599 (5), 1651-1664, 2021
82021
Modulation of peripheral Na+ channels and neuronal firing by n-butyl-p-aminobenzoate
O Thériault, H Poulin, A Sculptoreanu, WC De Groat, ME O’Leary, ...
European journal of pharmacology 727, 158-166, 2014
42014
De novo Y1460C missense variant in NaV1.1 impedes the pore region and results in epileptic encephalopathy
Q Plumereau, A Ebdalla, H Poulin, JP Appendino, MH Scantlebury, ...
Scientific Reports 12 (1), 17182, 2022
12022
Generation of a patient-specific iPSC cell line with cardiac arrhythmias and dilated cardiomyopathy (CBRCULi016-A), an isogenic control (CBRCULi016-A-1), and a paternal control …
M Djemai, D Jauvin, H Poulin, CA Chapotte-Baldacci, M Chahine
Stem Cell Research 75, 103308, 2024
2024
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