Anwar Anwar-Mohamed
TitleCited byYear
Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats
BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi
Toxicology and applied pharmacology 242 (1), 38-46, 2010
752010
Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver
BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi
Drug metabolism and disposition 39 (8), 1440-1450, 2011
632011
Regulation of CYP1A1 by heavy metals and consequences for drug metabolism
A Anwar-Mohamed, RH Elbekai, AOS El-Kadi
Expert opinion on drug metabolism & toxicology 5 (5), 501-521, 2009
612009
Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells
A Anwar-Mohamed, AOS El-Kadi
Cancer letters 275 (1), 93-101, 2009
592009
The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers
A Anwar-Mohamed, OS Degenhardt, MAM El Gendy, JM Seubert, ...
Toxicology in Vitro 25 (4), 785-795, 2011
492011
Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation
A Anwar-mohamed, BNM Zordoky, ME Aboutabl, AOS El-Kadi
Pharmacological research 61 (5), 410-418, 2010
422010
The tumor suppressor gene, RASSF1A, is essential for protection against inflammation-induced injury
M Gordon, M El-Kalla, Y Zhao, Y Fiteih, J Law, N Volodko, A Mohamed, ...
PloS one 8 (10), e75483, 2013
392013
A refined model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes
KH Barakat, A Anwar-Mohamed, JA Tuszynski, MJ Robins, DL Tyrrell, ...
Journal of chemical information and modeling 55 (2), 362-373, 2014
382014
A human ether-a-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
A Anwar-Mohamed, KH Barakat, R Bhat, SY Noskov, DL Tyrrell, ...
Toxicology letters 230 (3), 382-392, 2014
362014
Secondary cytotoxicity mediated by alveolar macrophages: a contribution to the total efficacy of nanoparticles in lung cancer therapy?
KMHD Al-Hallak, S Azarmi, A Anwar-Mohamed, WH Roa, R Löbenberg
European Journal of Pharmaceutics and Biopharmaceutics 76 (1), 112-119, 2010
322010
Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation
ZH Maayah, MAM El Gendy, AO El-Kadi, HM Korashy
Archives of toxicology 87 (5), 847-856, 2013
302013
Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice
A Anwar-Mohamed, G Abdelhamid, IEA Amara, AOS El-Kadi
Archives of toxicology 86 (6), 897-910, 2012
272012
Down-regulation of the carcinogen-metabolizing enzyme cytochrome P450 1a1 by vanadium
A Anwar-Mohamed, AOS El-Kadi
Drug Metabolism and Disposition 36 (9), 1819-1827, 2008
272008
Arsenite down-regulates cytochrome P450 1A1 at the transcriptional and posttranslational levels in human HepG2 cells
A Anwar-Mohamed, AOS El-Kadi
Free Radical Biology and Medicine 48 (10), 1399-1409, 2010
262010
20-Hydroxyeicosatetraenoic acid is a potential therapeutic target in cardiovascular diseases
O H Elshenawy, A Anwar-Mohamed, A OS El-Kadi
Current drug metabolism 14 (6), 706-719, 2013
252013
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation
HM Korashy, A Anwar-Mohamed, AA Soshilov, MS Denison, AOS El-Kadi
Chemical research in toxicology 24 (9), 1540-1548, 2011
252011
Induction of cytochrome P450 1a1 by the food flavoring agent, maltol
A Anwar-Mohamed, AOS El-Kadi
Toxicology in vitro 21 (4), 685-690, 2007
252007
Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics
AA El-Sherbeni, ME Aboutabl, BNM Zordoky, A Anwar-Mohamed, ...
The AAPS journal 15 (1), 112-122, 2013
242013
Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart
A Anwar-Mohamed, AA El-Sherbeni, SH Kim, HN Althurwi, BNM Zordoky, ...
Xenobiotica 42 (12), 1235-1247, 2012
242012
Mercury modulates the CYP1A1 at transcriptional and posttranslational levels in human hepatoma HepG2 cells
IEA Amara, A Anwar-Mohamed, AOS El-Kadi
Toxicology letters 199 (3), 225-233, 2010
242010
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