Anwar Anwar-Mohamed
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Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats
BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi
Toxicology and applied pharmacology 242 (1), 38-46, 2010
Regulation of CYP1A1 by heavy metals and consequences for drug metabolism
A Anwar-Mohamed, RH Elbekai, AOS El-Kadi
Expert opinion on drug metabolism & toxicology 5 (5), 501-521, 2009
Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver
BNM Zordoky, A Anwar-Mohamed, ME Aboutabl, AOS El-Kadi
Drug Metabolism and Disposition 39 (8), 1440-1450, 2011
Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells
A Anwar-Mohamed, AOS El-Kadi
Cancer letters 275 (1), 93-101, 2009
The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers
A Anwar-Mohamed, OS Degenhardt, MAM El Gendy, JM Seubert, ...
Toxicology in Vitro 25 (4), 785-795, 2011
Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation
A Anwar-mohamed, BNM Zordoky, ME Aboutabl, AOS El-Kadi
Pharmacological research 61 (5), 410-418, 2010
A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity
A Anwar-Mohamed, KH Barakat, R Bhat, SY Noskov, DL Tyrrell, ...
Toxicology letters 230 (3), 382-392, 2014
The tumor suppressor gene, RASSF1A, is essential for protection against inflammation-induced injury
M Gordon, M El-Kalla, Y Zhao, Y Fiteih, J Law, N Volodko, A Mohamed, ...
PloS one 8 (10), e75483, 2013
A refined model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes
KH Barakat, A Anwar-Mohamed, JA Tuszynski, MJ Robins, DL Tyrrell, ...
Journal of chemical information and modeling 55 (2), 362-373, 2015
Secondary cytotoxicity mediated by alveolar macrophages: a contribution to the total efficacy of nanoparticles in lung cancer therapy?
KMHD Al-Hallak, S Azarmi, A Anwar-Mohamed, WH Roa, R Löbenberg
European Journal of Pharmaceutics and Biopharmaceutics 76 (1), 112-119, 2010
Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation
ZH Maayah, MAM El Gendy, AO El-Kadi, HM Korashy
Archives of toxicology 87 (5), 847-856, 2013
Oxidative stress attenuates lipid synthesis and increases mitochondrial fatty acid oxidation in hepatoma cells infected with hepatitis C virus
DN Douglas, CH Pu, JT Lewis, R Bhat, A Anwar-Mohamed, M Logan, ...
Journal of biological chemistry 291 (4), 1974-1990, 2016
Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics
AA El-Sherbeni, ME Aboutabl, BNM Zordoky, A Anwar-Mohamed, ...
The AAPS journal 15 (1), 112-122, 2013
Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice
A Anwar-Mohamed, G Abdelhamid, IEA Amara, AOS El-Kadi
Archives of toxicology 86 (6), 897-910, 2012
Down-regulation of the carcinogen-metabolizing enzyme cytochrome P450 1a1 by vanadium
A Anwar-Mohamed, AOS El-Kadi
Drug metabolism and disposition 36 (9), 1819-1827, 2008
The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation
HM Korashy, A Anwar-Mohamed, AA Soshilov, MS Denison, AOS El-Kadi
Chemical research in toxicology 24 (9), 1540-1548, 2011
Clinical implications of 20-hydroxyeicosatetraenoic acid in the kidney, liver, lung and brain: an emerging therapeutic target
OH Elshenawy, SM Shoieb, A Mohamed, AOS El-Kadi
Pharmaceutics 9 (1), 9, 2017
Vinyl chloride metabolites potentiate inflammatory liver injury caused by LPS in mice
LC Anders, AL Lang, A Anwar-Mohamed, AN Douglas, AM Bushau, ...
Toxicological Sciences 151 (2), 312-323, 2016
20-Hydroxyeicosatetraenoic acid is a potential therapeutic target in cardiovascular diseases
O H Elshenawy, A Anwar-Mohamed, A OS El-Kadi
Current Drug Metabolism 14 (6), 706-719, 2013
Acute arsenic toxicity alters cytochrome P450 and soluble epoxide hydrolase and their associated arachidonic acid metabolism in C57Bl/6 mouse heart
A Anwar-Mohamed, AA El-Sherbeni, SH Kim, HN Althurwi, BNM Zordoky, ...
Xenobiotica 42 (12), 1235-1247, 2012
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