| Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 Å resolution D Ghosh, VZ Pletnev, DW Zhu, Z Wawrzak, WL Duax, W Pangborn, ... Structure 3 (5), 503-513, 1995 | 372 | 1995 |
| Crystal structure of human estrogenic 17β-hydroxysteroid dehydrogenase complexed with 17β-estradiol A Azzi, PH Rehse, DW Zhu, RL Campbell, F Labrie, SX Lin Nature structural biology 3 (8), 665-668, 1996 | 201 | 1996 |
| Subunit identity of the dimeric 17 beta-hydroxysteroid dehydrogenase from human placenta. SX Lin, F Yang, JZ Jin, R Breton, DW Zhu, V Luu-The, F Labrie Journal of Biological Chemistry 267 (23), 16182-16187, 1992 | 143 | 1992 |
| Binary and ternary crystal structure analyses of a novel inhibitor with 17β-HSD type 1: a lead compound for breast cancer therapy M Mazumdar, D Fournier, DW Zhu, C Cadot, D Poirier, SX Lin Biochemical Journal 424 (3), 357-366, 2009 | 93 | 2009 |
| Crystallization and preliminary X-ray diffraction analysis of the complex of human placental 17β-hydroxysteroid dehydrogenase with NADP+ DW Zhu, X Lee, R Breton, D Ghosh, W Pangborn, WL Duax, SX Lin Journal of molecular biology 234 (1), 242-244, 1993 | 81 | 1993 |
| Structural basis of the multispecificity demonstrated by 17β-hydroxysteroid dehydrogenase types 1 and 5 SX Lin, R Shi, W Qiu, A Azzi, DW Zhu, H Al Dabbagh, M Zhou Molecular and cellular endocrinology 248 (1-2), 38-46, 2006 | 65 | 2006 |
| Characterization of protein and virus crystals by quasi-planar wave X-ray topography: a comparison between crystals grown in solution and in agarose gel B Lorber, C Sauter, JD Ng, DW Zhu, R Giegé, O Vidal, MC Robert, ... Journal of crystal growth 204 (3), 357-368, 1999 | 56 | 1999 |
| Structure of the human 3α-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-Å resolution V Nahoum, A Gangloff, P Legrand, DW Zhu, L Cantin, BS Zhorov, F Labrie, ... Journal of Biological Chemistry 276 (45), 42091-42098, 2001 | 55 | 2001 |
| Growth kinetics, diffraction properties and effect of agarose on the stability of a novel crystal form of Thermus thermophilus aspartyl-tRNA synthetase-1 DW Zhu, B Lorber, C Sauter, JD Ng, P Bénas, C Le Grimellec, R Giegé Acta Crystallographica Section D: Biological Crystallography 57 (4), 552-558, 2001 | 54 | 2001 |
| 3D-structure of human estrogenic 17β-HSD1: binding with various steroids SX Lin, Q Han, A Azzi, DW Zhu, A Gongloff, RL Campbell The Journal of Steroid Biochemistry and Molecular Biology 69 (1-6), 425-429, 1999 | 51 | 1999 |
| Luu-The, V., Labrie, F., Breton, R. and Lin, SX (2001) Structure of the human 3α-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-Å resolution V Nahoum, A Gangloff, P Legrand, DW Zhu, L Cantin, BS Zhorov J. Biol. Chem 276, 42091-42098, 0 | 35 | |
| Attempts to rationalize protein crystallization using relative crystallizability DW Zhu, A Garneau, M Mazumdar, M Zhou, GJ Xu, SX Lin Journal of structural biology 154 (3), 297-302, 2006 | 33 | 2006 |
| An extensive study of protein phase diagram modification: increasing macromolecular crystallizability by temperature screening YB Lin, DW Zhu, T Wang, J Song, YS Zou, YL Zhang, SX Lin Crystal Growth and Design 8 (12), 4277-4283, 2008 | 32 | 2008 |
| From conventional crystallization to better crystals from space: a review on pilot crystallogenesis studies with aspartyl-tRNA synthetases B Lorber, A Théobald-Dietrich, C Charron, C Sauter, JD Ng, DW Zhu, ... Acta Crystallographica Section D: Biological Crystallography 58 (10), 1674-1680, 2002 | 24 | 2002 |
| Rapid purification yielding highly active 17β-hydroxysteroid dehydrogenase: application of hydrophobic interaction and affinity fast protein liquid chromatography F Yang, DW Zhu, JY Wang, SX Lin Journal of Chromatography B: Biomedical Sciences and Applications 582 (1-2 …, 1992 | 23 | 1992 |
| V. Luu-The, F. Labrie SX Lin, F Yang, JZ Jin, R Breton, DW Zhu J. Biol. Chem 267 (16), 182, 1992 | 22 | 1992 |
| Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity B Zhang, DW Zhu, XJ Hu, M Zhou, P Shang, SX Lin The Journal of Steroid Biochemistry and Molecular Biology 141, 135-143, 2014 | 21 | 2014 |
| Human 3α-hydroxysteroid dehydrogenase type 3: structural clues of 5α-DHT reverse binding and enzyme down-regulation decreasing MCF7 cell growth B Zhang, XJ Hu, XQ Wang, JF Thériault, DW Zhu, P Shang, F Labrie, ... Biochemical Journal 473 (8), 1037-1046, 2016 | 19 | 2016 |
| The crystallogenesis of a human estradiol dehydrogenase-substrate complex DW Zhu, A Azzi, P Rehse, SX Lin Journal of crystal growth 168 (1-4), 275-279, 1996 | 19 | 1996 |
| Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+ reveal the mechanism of substrate inhibition T Li, P Stephen, DW Zhu, R Shi, SX Lin The FEBS journal 286 (11), 2155-2166, 2019 | 17 | 2019 |
Debashis GhoshProfessor, Department of Pharmacology, SUNY UpstateAdresse e-mail validée de upstate.edu
