| Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction DE Kaufmann, DG Kavanagh, F Pereyra, JJ Zaunders, EW Mackey, ... Nature immunology 8 (11), 1246-1254, 2007 | 577 | 2007 |
| Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication A Schneidewind, MA Brockman, R Yang, RI Adam, B Li, S Le Gall, ... Journal of virology 81 (22), 12382-12393, 2007 | 364 | 2007 |
| HLA-B57/B* 5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T … T Miura, MA Brockman, A Schneidewind, M Lobritz, F Pereyra, A Rathod, ... Journal of virology 83 (6), 2743-2755, 2009 | 302 | 2009 |
| Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A MA Brockman, A Schneidewind, M Lahaie, A Schmidt, T Miura, I DeSouza, ... Journal of virology 81 (22), 12608-12618, 2007 | 297 | 2007 |
| IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells MA Brockman, DS Kwon, DP Tighe, DF Pavlik, PC Rosato, J Sela, ... Blood 114 (2), 346-356, 2009 | 260 | 2009 |
| TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infection H Chen, ZM Ndhlovu, D Liu, LC Porter, JW Fang, S Darko, MA Brockman, ... Nature immunology 13 (7), 691, 2012 | 226 | 2012 |
| Herpes simplex virus. TJ Taylor, MA Brockman, EE McNamee, DM Knipe Frontiers in bioscience: a journal and virtual library 7, d752-64, 2002 | 192 | 2002 |
| HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins ZL Brumme, M John, JM Carlson, CJ Brumme, D Chan, MA Brockman, ... PloS one 4 (8), e6687, 2009 | 182 | 2009 |
| Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid A Schneidewind, MA Brockman, J Sidney, YE Wang, H Chen, ... Journal of virology 82 (11), 5594-5605, 2008 | 170 | 2008 |
| Responsiveness of HIV-specific CD4 T cells to PD-1 blockade F Porichis, DS Kwon, J Zupkosky, DP Tighe, A McMullen, MA Brockman, ... Blood, The Journal of the American Society of Hematology 118 (4), 965-974, 2011 | 163 | 2011 |
| HIV Increases HCV Replication in a TGF-β1–Dependent Manner W Lin, EM Weinberg, AW Tai, LF Peng, MA Brockman, KA Kim, SS Kim, ... Gastroenterology 134 (3), 803-811, 2008 | 155 | 2008 |
| HLA-associated alterations in replication capacity of chimeric NL4-3 viruses carrying gag-protease from elite controllers of human immunodeficiency virus type 1 T Miura, MA Brockman, ZL Brumme, CJ Brumme, F Pereyra, A Trocha, ... Journal of virology 83 (1), 140-149, 2009 | 148 | 2009 |
| Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes T Miura, MA Brockman, CJ Brumme, ZL Brumme, JM Carlson, F Pereyra, ... Journal of virology 82 (17), 8422-8430, 2008 | 148 | 2008 |
| Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection MA Brockman, ZL Brumme, CJ Brumme, T Miura, J Sela, PC Rosato, ... Journal of virology 84 (22), 11937-11949, 2010 | 142 | 2010 |
| Humoral response to herpes simplex virus is complement-dependent XJ Da Costa, MA Brockman, E Alicot, M Ma, MB Fischer, X Zhou, ... Proceedings of the National Academy of Sciences 96 (22), 12708-12712, 1999 | 140 | 1999 |
| Impaired replication capacity of acute/early viruses in persons who become HIV controllers T Miura, ZL Brumme, MA Brockman, P Rosato, J Sela, CJ Brumme, ... Journal of virology 84 (15), 7581-7591, 2010 | 136 | 2010 |
| Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection M Lichterfeld, GY Xu, SK Mui, KL Williams, A Trocha, MA Brockman, ... Journal of virology 81 (8), 4199-4214, 2007 | 135 | 2007 |
| Construction, phenotypic analysis, and immunogenicity of a UL5/UL29 double deletion mutant of herpes simplex virus 2 X Da Costa, MF Kramer, J Zhu, MA Brockman, DM Knipe Journal of Virology 74 (17), 7963-7971, 2000 | 107 | 2000 |
| Up-regulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands A Meier, A Bagchi, HK Sidhu, G Alter, TJ Suscovich, DG Kavanagh, ... AIDS (London, England) 22 (5), 655, 2008 | 105 | 2008 |
| HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFκB W Lin, G Wu, S Li, EM Weinberg, K Kumthip, LF Peng, J Méndez-Navarro, ... Journal of Biological Chemistry 286 (4), 2665-2674, 2011 | 104 | 2011 |
Zabrina BrummeAssociate Professor, Faculty of Health Sciences, Simon Fraser UniversityVerified email at sfu.ca
