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Yu Sun
Yu Sun
Verified email at princeton.edu
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Vascular endothelial cells and innate immunity
Y Shao, J Saredy, WY Yang, Y Sun, Y Lu, F Saaoud, C Drummer IV, ...
Arteriosclerosis, thrombosis, and vascular biology 40 (6), e138-e152, 2020
1962020
ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes
Y Sun, Y Lu, J Saredy, X Wang, C Drummer IV, Y Shao, F Saaoud, K Xu, ...
Redox biology 37, 101696, 2020
1742020
Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation
X Li, L Wang, P Fang, Y Sun, X Jiang, H Wang, XF Yang
Journal of Biological Chemistry 293 (28), 11033-11045, 2018
742018
Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers
F Saaoud, CD IV, Y Shao, Y Sun, Y Lu, K Xu, D Ni, X Jiang, H Wang, ...
Pharmacology & therapeutics 220, 107715, 2021
732021
Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune …
X Li, P Fang, Y Sun, Y Shao, WY Yang, X Jiang, H Wang, X Yang
Redox biology 28, 101373, 2020
732020
Low-intensity ultrasound-induced anti-inflammatory effects are mediated by several new mechanisms including gene induction, immunosuppressor cell promotion, and enhancement of …
Q Yang, GK Nanayakkara, C Drummer, Y Sun, C Johnson, R Cueto, H Fu, ...
Frontiers in Physiology 8, 818, 2017
722017
Trained immunity and reactivity of macrophages and endothelial cells
C Drummer IV, F Saaoud, Y Shao, Y Sun, K Xu, Y Lu, D Ni, D Atar, ...
Arteriosclerosis, thrombosis, and vascular biology 41 (3), 1032-1046, 2021
692021
Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18-and sirtuin-1-independent pathways
Y Li, G Nanayakkara, Y Sun, X Li, L Wang, R Cueto, Y Shao, H Fu, ...
Journal of Hematology & Oncology 10, 1-23, 2017
572017
Endothelial immunity trained by coronavirus infections, DAMP stimulations and regulated by anti-oxidant NRF2 may contribute to inflammations, myelopoiesis, COVID-19 cytokine …
Y Shao, J Saredy, K Xu, Y Sun, F Saaoud, C Drummer IV, Y Lu, JJ Luo, ...
Frontiers in immunology 12, 653110, 2021
502021
Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells–novel …
Y Lu, Y Sun, C Drummer IV, GK Nanayakkara, Y Shao, F Saaoud, ...
Redox biology 24, 101221, 2019
502019
The microbial metabolite trimethylamine N-oxide links vascular dysfunctions and the autoimmune disease rheumatoid arthritis
MM Chan, X Yang, H Wang, F Saaoud, Y Sun, D Fong
Nutrients 11 (8), 1821, 2019
472019
Uremic toxins are conditional danger-or homeostasis-associated molecular patterns
Y Sun, C Johnson, J Zhou, L Wang, YF Li, Y Lu, G Nanayakkara, H Fu, ...
Frontiers in bioscience (Landmark edition) 23, 348, 2018
432018
End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs-A novel multiple-hit model for disease progression
R Zhang, J Saredy, Y Shao, T Yao, L Liu, F Saaoud, WY Yang, Y Sun, ...
Redox biology 34, 101460, 2020
422020
Co-signaling receptors regulate T-cell plasticity and immune tolerance
H Shen, N Wu, G Nanayakkara, H Fu, Q Yang, WY Yang, A Li, Y Sun, ...
Frontiers in bioscience (Landmark edition) 24, 96, 2019
402019
Liver ischemia reperfusion injury, enhanced by trained immunity, is attenuated in caspase 1/caspase 11 double gene knockout mice
AM Fagenson, K Xu, F Saaoud, G Nanayakkara, NC Jhala, L Liu, ...
Pathogens 9 (11), 879, 2020
382020
IL-35 promotes CD4+ Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms
Y Shao, WY Yang, F Saaoud, C Drummer IV, Y Sun, K Xu, Y Lu, H Shan, ...
JCI insight 6 (19), 2021
362021
Tissue Treg secretomes and transcription factors shared with stem cells contribute to a Treg niche to maintain Treg-ness with 80% innate immune pathways, and functions of …
R Zhang, K Xu, Y Shao, Y Sun, J Saredy, E Cutler, T Yao, M Liu, L Liu, ...
Frontiers in Immunology 11, 632239, 2021
342021
Twenty novel disease group-specific and 12 new shared macrophage pathways in eight groups of 34 diseases including 24 inflammatory organ diseases and 10 types of tumors
B Lai, J Wang, A Fagenson, Y Sun, J Saredy, Y Lu, G Nanayakkara, ...
Frontiers in Immunology 10, 2612, 2019
312019
A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors
L Wang, G Nanayakkara, Q Yang, H Tan, C Drummer, Y Sun, Y Shao, ...
Journal of hematology & oncology 10, 1-41, 2017
302017
Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators
M Liu, J Saredy, R Zhang, Y Shao, Y Sun, WY Yang, J Wang, L Liu, ...
Frontiers in Immunology 11, 554301, 2020
272020
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