PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking A Vaid, R Ranjan, WA Smythe, HC Hoppe, P Sharma Blood, The Journal of the American Society of Hematology 115 (12), 2500-2507, 2010 | 164 | 2010 |
Comparison of dual therapies for lowering blood pressure in black Africans DB Ojji, B Mayosi, V Francis, M Badri, V Cornelius, W Smythe, N Kramer, ... New England Journal of Medicine 380 (25), 2429-2439, 2019 | 118 | 2019 |
A semimechanistic pharmacokinetic-enzyme turnover model for rifampin autoinduction in adult tuberculosis patients W Smythe, A Khandelwal, C Merle, R Rustomjee, M Gninafon, M Bocar Lo, ... Antimicrobial agents and chemotherapy 56 (4), 2091-2098, 2012 | 105 | 2012 |
Actin is required for endocytic trafficking in the malaria parasite Plasmodium falciparum WA Smythe, KA Joiner, HC Hoppe Cellular microbiology 10 (2), 452-464, 2008 | 77 | 2008 |
Bioavailability of two licensed paediatric rifampicin suspensions: implications for quality control programmes H McIlleron, H Hundt, W Smythe, A Bekker, J Winckler, L Van der Laan, ... The International Journal of Tuberculosis and Lung Disease 20 (7), 915-919, 2016 | 26 | 2016 |
Gatifloxacin pharmacokinetics/pharmacodynamics–based optimal dosing for pulmonary and meningeal multidrug-resistant tuberculosis D Deshpande, JG Pasipanodya, S Srivastava, P Bendet, T Koeuth, ... Clinical Infectious Diseases 67 (suppl_3), S274-S283, 2018 | 24 | 2018 |
Evaluation of initial and steady-state gatifloxacin pharmacokinetics and dose in pulmonary tuberculosis patients by using Monte Carlo simulations W Smythe, CS Merle, R Rustomjee, M Gninafon, MB Lo, O Bah-Sow, ... Antimicrobial agents and chemotherapy 57 (9), 4164-4171, 2013 | 23 | 2013 |
Bocar Lo M, Sow OB, Olliaro PL, Lienhardt C, Horton J, Smith P, McIlleron H, Simonsson USH. 2012. A semimechanistic pharmacokinetic-enzyme turnover model for rifampin … W Smythe, A Khandelwal, C Merle, R Rustomjee, M Gninafon Antimicrob Agents Chemother 56 (4), 2091-2098, 0 | 21 | |
Quality assurance of rifampicin-containing fixed-drug combinations in South Africa: dosing implications MT Chirehwa, L Wiesner, B Wright, W Smythe, N Kramer, H McIlleron The International Journal of Tuberculosis and Lung Disease 22 (5), 537-543, 2018 | 15 | 2018 |
Pharmacokinetic profile and safety of adjusted doses of darunavir/ritonavir with rifampicin in people living with HIV I Ebrahim, G Maartens, L Wiesner, C Orrell, W Smythe, H McIlleron Journal of Antimicrobial Chemotherapy 75 (4), 1019-1025, 2020 | 14 | 2020 |
Artificial intelligence–derived 3-way concentration-dependent antagonism of gatifloxacin, pyrazinamide, and rifampicin during treatment of pulmonary tuberculosis JG Pasipanodya, W Smythe, CS Merle, PL Olliaro, D Deshpande, ... Clinical Infectious Diseases 67 (suppl_3), S284-S292, 2018 | 13 | 2018 |
Rationale and design of the comparison of 3 combination therapies in lowering blood pressure in black Africans (CREOLE study): 2× 3 factorial randomized single-blind … DB Ojji, N Poulter, A Damasceno, K Sliwa, W Smythe, N Kramer, M Badri, ... American Heart Journal 202, 5-12, 2018 | 12 | 2018 |
A population pharmacokinetic model for rifampicin auto-induction P Denti, W Smythe, US Simonsson, R Rustomjee, P Onyebujoh, P Smith, ... 3rd International Workshop on Clinical Pharmacology of TB Drugs, 2010 | 12 | 2010 |
Characterizing population pharmacokinetic/pharmacodynamic relationships in pulmonary tuberculosis infected adults using nonlinear mixed effects modelling WA Smythe | 6 | 2016 |
Effect of 3, 2-drug combinations of antihypertensive therapies on blood pressure variability in black African patients: Secondary analyses of the CREOLE Trial DB Ojji, V Cornelius, G Partington, V Francis, S Pandie, W Smythe, ... Hypertension 79 (11), 2593-2600, 2022 | 3 | 2022 |
A differential response to antihypertensive therapy in African men and women: insights from the CREOLE trial DB Ojji, GL Shedul, M Sani, OS Ogah, A Dzudie, F Barasa, C Mondo, ... American Journal of Hypertension 35 (6), 551-560, 2022 | 3 | 2022 |
Investigational Medicinal Product (IMP) Management W Smythe, N Kramer A Comprehensive and Practical Guide to Clinical Trials, 103-117, 2017 | 1 | 2017 |
Bioavailability of two licensed paediatric rifampicin suspensions: implications for quality control programmes AC Hesseling, HJ Zar, H Hundt, H McIlleron, A van Rie, L Wiesner, ... International Union Against Tuberculosis and Lung Disease, 2016 | | 2016 |
Characterising the role of actin and PI (3) kinases in endocytosis in the malaria parasite Plasmodium falciparum WA Smythe | | 2007 |
Population Approach Group Europe Population Approach Group Europe W Smythe | | |