| Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease TR Flower, LS Chesnokova, CA Froelich, C Dixon, SN Witt Journal of molecular biology 351 (5), 1081-1100, 2005 | 307 | 2005 |
| Ethanolamine and phosphatidylethanolamine: partners in health and disease D Patel, SN Witt Oxidative medicine and cellular longevity 2017, 2017 | 274 | 2017 |
| The unfolding story of the Escherichia coli Hsp70 DnaK: is DnaK a holdase or an unfoldase? SV Slepenkov, SN Witt Molecular microbiology 45 (5), 1197-1206, 2002 | 135 | 2002 |
| Mechanism of cytochrome c oxidase-catalyzed dioxygen reduction at low temperatures. Evidence for two intermediates at the three-electron level and entropic promotion of the … DF Blair, SN Witt, SI Chan Journal of the American Chemical Society 107 (25), 7389-7399, 1985 | 125 | 1985 |
| Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease S Wang, S Zhang, LC Liou, Q Ren, Z Zhang, GA Caldwell, KA Caldwell, ... Proceedings of the National Academy of Sciences 111 (38), E3976-E3985, 2014 | 97 | 2014 |
| Hsp70 molecular chaperones and Parkinson's disease SN Witt Biopolymers 93 (3), 218-228, 2010 | 94 | 2010 |
| Characterization of a lidless form of the molecular chaperone DnaK G Buczynski, SV Slepenkov, MG Sehorn, SN Witt Journal of Biological Chemistry 276 (29), 27231-27236, 2001 | 91 | 2001 |
| α‐Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease SN Witt, TR Flower FEMS yeast research 6 (8), 1107-1116, 2006 | 78 | 2006 |
| YGR198w (YPP1) targets A30P α-synuclein to the vacuole for degradation TR Flower, C Clark-Dixon, C Metoyer, H Yang, R Shi, Z Zhang, SN Witt The Journal of cell biology 177 (6), 1091-1104, 2007 | 76 | 2007 |
| Novel suppressors of α-synuclein toxicity identified using yeast J Liang, C Clark-Dixon, S Wang, TR Flower, T Williams-Hart, R Zweig, ... Human molecular genetics 17 (23), 3784-3795, 2008 | 72 | 2008 |
| Evidence for a ferryl Fea3 in oxygenated cytochrome c oxidase. SN Witt, SI Chan Journal of Biological Chemistry 262 (4), 1446-1448, 1987 | 70 | 1987 |
| Molecular chaperones, alpha-synuclein, and neurodegeneration SN Witt Molecular neurobiology 47, 552-560, 2013 | 69 | 2013 |
| Kinetic analysis of interdomain coupling in a lidless variant of the molecular chaperone DnaK: DnaK's lid inhibits transition to the low affinity state SV Slepenkov, SN Witt Biochemistry 41 (40), 12224-12235, 2002 | 64 | 2002 |
| Peptide-induced conformational changes in the molecular chaperone DnaK SV Slepenkov, SN Witt Biochemistry 37 (47), 16749-16756, 1998 | 63 | 1998 |
| The insect antimicrobial peptide, L-pyrrhocoricin, binds to and stimulates the ATPase activity of both wild-type and lidless DnaK LS Chesnokova, SV Slepenkov, SN Witt FEBS letters 565 (1-3), 65-69, 2004 | 61 | 2004 |
| Kinetics of the reactions of the Escherichia coli molecular chaperone DnaK with ATP: evidence that a three-step reaction precedes ATP hydrolysis SV Slepenkov, SN Witt Biochemistry 37 (4), 1015-1024, 1998 | 55 | 1998 |
| GrpE accelerates peptide binding and release from the high affinity state of DnaK A Mally, SN Witt Nature Structural & Molecular Biology 8 (3), 254-257, 2001 | 54 | 2001 |
| α-Synuclein disrupts stress signaling by inhibiting polo-like kinase Cdc5/Plk2 S Wang, B Xu, LC Liou, Q Ren, S Huang, Y Luo, Z Zhang, SN Witt Proceedings of the National Academy of Sciences 109 (40), 16119-16124, 2012 | 52 | 2012 |
| Defects in Very Long Chain Fatty Acid Synthesis Enhance Alpha-Synuclein Toxicity in a Yeast Model of Parkinson's Disease YJ Lee, S Wang, SR Slone, TA Yacoubian, SN Witt PloS one 6 (1), e15946, 2011 | 52 | 2011 |
| Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast X Liu, YJ Lee, LC Liou, Q Ren, Z Zhang, S Wang, SN Witt Human molecular genetics 20 (17), 3401-3414, 2011 | 47 | 2011 |
