Kevin R Brown
TitleCited byYear
High-throughput mapping of a dynamic signaling network in mammalian cells
M Barrios-Rodiles, KR Brown, B Ozdamar, R Bose, Z Liu, RS Donovan, ...
Science 307 (5715), 1621-1625, 2005
7312005
Online predicted human interaction database
KR Brown, I Jurisica
Bioinformatics 21 (9), 2076-2082, 2005
6532005
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
5302015
Unequal evolutionary conservation of human protein interactions in interologous networks
KR Brown, I Jurisica
Genome biology 8 (5), R95, 2007
3032007
Essential gene profiles in breast, pancreatic, and ovarian cancer cells
R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ...
Cancer discovery 2 (2), 172-189, 2012
2302012
NAViGaTOR: network analysis, visualization and graphing Toronto
KR Brown, D Otasek, M Ali, MJ McGuffin, W Xie, B Devani, IL Toch, ...
Bioinformatics 25 (24), 3327-3329, 2009
1852009
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ...
Cell 164 (1-2), 293-309, 2016
1722016
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6
YL Deribe, P Wild, A Chandrashaker, J Curak, MHH Schmidt, ...
Sci. Signal. 2 (102), ra84-ra84, 2009
1622009
A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers
L Gortzak-Uzan, A Ignatchenko, AI Evangelou, M Agochiya, KA Brown, ...
Journal of proteome research 7 (01), 339-351, 2007
1582007
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
T Hart, KR Brown, F Sircoulomb, R Rottapel, J Moffat
Molecular systems biology 10 (7), 2014
1362014
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60, 2017
1032017
Penicillin man: Alexander Fleming and the antibiotic revolution
K Brown
The History Press, 2005
962005
Systematic identification of SH3 domain‐mediated human protein–protein interactions by peptide array target screening
C Wu, MH Ma, KR Brown, M Geisler, L Li, E Tzeng, CYH Jia, I Jurisica, ...
Proteomics 7 (11), 1775-1785, 2007
892007
Transcriptional targets of hepatocyte growth factor signaling and Ki-ras oncogene activation in colorectal cancer
IM Seiden-Long, KR Brown, W Shih, DA Wigle, N Radulovich, I Jurisica, ...
Oncogene 25 (1), 91, 2006
782006
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes
W Zhang, KP Wu, MA Sartori, HB Kamadurai, A Ordureau, C Jiang, ...
Molecular cell 62 (1), 121-136, 2016
752016
Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes
B Cox, T Kislinger, DA Wigle, A Kannan, K Brown, T Okubo, B Hogan, ...
Molecular systems biology 3 (1), 2007
722007
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities
FJ Vizeacoumar, R Arnold, FS Vizeacoumar, M Chandrashekhar, ...
Molecular systems biology 9 (1), 2013
672013
Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity
M Usenovic, AL Knight, A Ray, V Wong, KR Brown, GA Caldwell, ...
Human molecular genetics 21 (17), 3785-3794, 2012
662012
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens
T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ...
G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017
652017
Analysis of hepatic glycogen‐associated proteins
D Stapleton, C Nelson, K Parsawar, D McClain, R Gilbert‐Wilson, ...
Proteomics 10 (12), 2320-2329, 2010
592010
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Articles 1–20