| Adjuvant and neoadjuvant therapy for breast cancer T Shien, H Iwata Japanese journal of clinical oncology 50 (3), 225-229, 2020 | 166 | 2020 |
| Primary tumor resection improves the survival of younger patients with metastatic breast cancer T Shien, T Kinoshita, C Shimizu, T Hojo, N Taira, H Doihara, ... Oncology reports 21 (3), 827-832, 2009 | 113 | 2009 |
| Estrogen receptor (ER) mRNA expression and molecular subtype distribution in ER-negative/progesterone receptor-positive breast cancers M Itoh, T Iwamoto, J Matsuoka, T Nogami, T Motoki, T Shien, N Taira, ... Breast cancer research and treatment 143, 403-409, 2014 | 103 | 2014 |
| Distinct gene expression profiles between primary breast cancers and brain metastases from pair-matched samples T Iwamoto, N Niikura, R Ogiya, H Yasojima, K Watanabe, C Kanbayashi, ... Scientific reports 9 (1), 13343, 2019 | 94 | 2019 |
| Unmet information needs and quality of life in young breast cancer survivors in Japan M Miyashita, S Ohno, A Kataoka, E Tokunaga, N Masuda, T Shien, ... Cancer nursing 38 (6), E1-E11, 2015 | 94 | 2015 |
| The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases … H Ikeda, N Taira, F Hara, T Fujita, H Yamamoto, J Soh, S Toyooka, ... Breast Cancer Research 12, 1-12, 2010 | 82 | 2010 |
| A randomized controlled trial comparing primary tumour resection plus systemic therapy with systemic therapy alone in metastatic breast cancer (PRIM-BC): Japan Clinical … T Shien, K Nakamura, T Shibata, T Kinoshita, K Aogi, T Fujisawa, ... Japanese journal of clinical oncology 42 (10), 970-973, 2012 | 72 | 2012 |
| The international collaboration of active surveillance trials for low-risk DCIS (LORIS, LORD, COMET, LORETTA). C Kanbayashi, AM Thompson, ESS Hwang, AH Partridge, DW Rea, ... Journal of Clinical Oncology 37 (15_suppl), TPS603-TPS603, 2019 | 65 | 2019 |
| Tumor inhibitory effect of gefitinib (ZD1839, Iressa) and taxane combination therapy in EGFR‐overexpressing breast cancer cell lines (MCF7/ADR, MDA‐MB‐231) D Takabatake, T Fujita, T Shien, K Kawasaki, N Taira, S Yoshitomi, ... International journal of cancer 120 (1), 181-188, 2007 | 64 | 2007 |
| Antitumor effect of gefitinib (‘Iressa’) on esophageal squamous cell carcinoma cell lines in vitro and in vivo F Hara, M Aoe, H Doihara, N Taira, T Shien, H Takahashi, S Yoshitomi, ... Cancer letters 226 (1), 37-47, 2005 | 62 | 2005 |
| 21-Gene expression profile assay on core needle biopsies predicts responses to neoadjuvant endocrine therapy in breast cancer patients S Akashi-Tanaka, C Shimizu, M Ando, T Shibata, N Katsumata, T Kouno, ... The Breast 18 (3), 171-174, 2009 | 58 | 2009 |
| Clinicopathological features of young patients (< 35 years of age) with breast cancer in a Japanese Breast Cancer Society supported study A Kataoka, E Tokunaga, N Masuda, T Shien, K Kawabata, M Miyashita Breast cancer 21, 643-650, 2014 | 57 | 2014 |
| TNM classification of malignant tumors (Breast Cancer Study Group) M Sawaki, T Shien, H Iwata Japanese journal of clinical oncology 49 (3), 228-231, 2019 | 56 | 2019 |
| Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR‐TKIs in non‐small cell lung cancer H Sato, H Yamamoto, M Sakaguchi, K Shien, S Tomida, T Shien, H Ikeda, ... Cancer Science 109 (10), 3183-3196, 2018 | 56 | 2018 |
| Combination treatment with fulvestrant and various cytotoxic agents (doxorubicin, paclitaxel, docetaxel, vinorelbine, and 5‐fluorouracil) has a synergistic effect in estrogen … H Ikeda, N Taira, T Nogami, K Shien, M Okada, T Shien, H Doihara, ... Cancer science 102 (11), 2038-2042, 2011 | 56 | 2011 |
| Immunohistochemical K i67 labeling index has similar proliferation predictive power to various gene signatures in breast cancer N Niikura, T Iwamoto, S Masuda, N Kumaki, T Xiaoyan, M Shirane, K Mori, ... Cancer science 103 (8), 1508-1512, 2012 | 55 | 2012 |
| Clinical and pathological features of intracystic papillary carcinoma of the breast T Akagi, T Kinoshita, T Shien, T Hojo, S Akashi-Tanaka, Y Murata Surgery today 39, 5-8, 2009 | 54 | 2009 |
| Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor‑positive/human epidermal growth factor receptor … Y Miyoshi, T Shien, A Ogiya, N Ishida, K Yamazaki, R Horii, Y Horimoto, ... Oncology letters 17 (2), 2177-2186, 2019 | 52 | 2019 |
| Effects of lifestyle and single nucleotide polymorphisms on breast cancer risk: a case–control study in Japanese women T Mizoo, N Taira, K Nishiyama, T Nogami, T Iwamoto, T Motoki, T Shien, ... BMC cancer 13, 1-15, 2013 | 51 | 2013 |
| Clinicopathological factors predicting early and late distant recurrence in estrogen receptor-positive, HER2-negative breast cancer H Yamashita, A Ogiya, T Shien, Y Horimoto, N Masuda, T Inao, T Osako, ... Breast Cancer 23, 830-843, 2016 | 47 | 2016 |
