Samuel Aparicio

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Sohrab ShahMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Marco MarraBC Cancer Agency; University of British Columbia, Genome Sciences CentreVerified email at bcgsc.ca
David HuntsmanBC Cancer AgencyVerified email at bccancer.bc.ca
Suet Feung ChinUniversity of CambridgeVerified email at cam.ac.uk
Martin HirstUniversity of British ColumbiaVerified email at bcgsc.ca
Oscar M RuedaMRC Investigator, Programme Leader, MRC-Biostatistics Unit. University of CambridgeVerified email at mrc-bsu.cam.ac.uk
Gavin HaFred Hutchinson Cancer Research CenterVerified email at fredhutch.org
H Raza AliGroup Leader, CRUK Cambridge Institute, University of CambridgeVerified email at cruk.cam.ac.uk
Ali BashashatiUniversity of British Columbia/Vancouver Coastal Health Research InstituteVerified email at bccrc.ca
Jiarui DingAsst. Professor, Computer Science, University of British ColumbiaVerified email at ubc.ca
Gregg B MorinSenior Scientist of Genome Sciences Centre, British Columbia Cancer AgencyVerified email at bcgsc.ca
Nuno Barbosa-MoraisResearch Group Leader, Instituto de Medicina Molecular - LisbonVerified email at medicina.ulisboa.pt
Ryan D. MorinProfessor, Simon Fraser University; Scientist at Genome Sciences Centre, BC Cancer AgencyVerified email at sfu.ca
Paul PharoahCedars-Sinai Medical CenterVerified email at cshs.org
Greg ElgarDirector of Sequencing, Research & Development. Genomics England and QMULVerified email at genomicsengland.co.uk
Andrew TeschendorffCAS Key Lab of Computational Biology, Shanghai Institute of Nutrition and Health, ShanghaiVerified email at sinh.ac.cn
Gholamreza (Reza) HaffariProfessor and ARC Future Fellow, DSAI Dept, Monash UniversityVerified email at monash.edu
Randy D GascoyneProfessor of Pathology, University of British ColumbiaVerified email at bccancer.bc.ca
Dr Anna GitDepartment of Biochemistry, University of CambridgeVerified email at cam.ac.uk
Ermanno GherardiUniversity of PaviaVerified email at unipv.it

Samuel Aparicio

UBC, BC Cancer Agency, Vancouver

Verified email at bccrc.ca - Homepage

genomics cancer evolution single cell biology computational biology


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Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013	10204	2013
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ... Nature 486 (7403), 346-352, 2012	6172	2012
The GPR54 Gene as a Regulator of Puberty SB Seminara, S Messager, EE Chatzidaki, RR Thresher, JS Acierno Jr, ... New England Journal of Medicine 349 (17), 1614-1627, 2003	3098	2003
The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012	2317	2012
Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012	2119	2012
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin RD Morin, NA Johnson, TM Severson, AJ Mungall, J An, R Goya, JE Paul, ... Nature genetics 42 (2), 181-185, 2010	1997	2010
ARID1A mutations in endometriosis-associated ovarian carcinomas KC Wiegand, SP Shah, OM Al-Agha, Y Zhao, K Tse, T Zeng, J Senz, ... New England Journal of Medicine 363 (16), 1532-1543, 2010	1957	2010
The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012	1939	2012
Whole-genome shotgun assembly and analysis of the genome of Fugu rubripes S Aparicio, J Chapman, E Stupka, N Putnam, J Chia, P Dehal, ... Science 297 (5585), 1301-1310, 2002	1890	2002
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1852*	2020
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes B Pereira, SF Chin, OM Rueda, HKM Vollan, E Provenzano, HA Bardwell, ... Nature communications 7 (1), 1-16, 2016	1651	2016
The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012	1593	2012
Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54 S Messager, EE Chatzidaki, D Ma, AG Hendrick, D Zahn, J Dixon, ... Proceedings of the National Academy of Sciences 102 (5), 1761-1766, 2005	1475	2005
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution SP Shah, RD Morin, J Khattra, L Prentice, T Pugh, A Burleigh, A Delaney, ... Nature 461 (7265), 809-813, 2009	1342	2009
Eleven grand challenges in single-cell data science D Lähnemann, J Köster, E Szczurek, DJ McCarthy, SC Hicks, ... Genome biology 21, 1-35, 2020	1050	2020
PyClone: statistical inference of clonal population structure in cancer A Roth, J Khattra, D Yap, A Wan, E Laks, J Biele, G Ha, S Aparicio, ... Nature methods 11 (4), 396-398, 2014	1000	2014
Mutation of FOXL2 in granulosa-cell tumors of the ovary SP Shah, M Köbel, J Senz, RD Morin, BA Clarke, KC Wiegand, G Leung, ... New England Journal of Medicine 360 (26), 2719-2729, 2009	873	2009
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome S Brenner, G Elgar, R Sanford, A Macrae, B Venkatesh, S Aparicio Nature 366 (6452), 265-268, 1993	755	1993
Patterns of somatic structural variation in human cancer genomes Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ... Nature 578 (7793), 112-121, 2020	754	2020
Eomesodermin is required for mouse trophoblast development and mesoderm formation AP Russ, S Wattler, WH Colledge, SAJR Aparicio, MBL Carlton, JJ Pearce, ... Nature 404 (6773), 95-99, 2000	737	2000

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