Hans-Guido Wendel
TitleCited byYear
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
HG Wendel, E de Stanchina, JS Fridman, A Malina, S Ray, S Kogan, ...
Nature 428 (6980), 332, 2004
10342004
Dissecting eIF4E action in tumorigenesis
HG Wendel, RLA Silva, A Malina, JR Mills, H Zhu, T Ueda, ...
Genes & development 21 (24), 3232-3237, 2007
4272007
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ...
Nature cell biology 12 (4), 372, 2010
3262010
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
AL Wolfe, K Singh, Y Zhong, P Drewe, VK Rajasekhar, VR Sanghvi, ...
Nature 513 (7516), 65, 2014
2792014
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ...
Nature genetics 43 (7), 673, 2011
2392011
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ...
Nature genetics 43 (7), 673, 2011
2382011
mTORC1 promotes survival through translational control of Mcl-1
JR Mills, Y Hippo, F Robert, SMH Chen, A Malina, CJ Lin, U Trojahn, ...
Proceedings of the National Academy of Sciences 105 (31), 10853-10858, 2008
2292008
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
ME Bordeleau, F Robert, B Gerard, L Lindqvist, SMH Chen, HG Wendel, ...
The Journal of clinical investigation 118 (7), 2651-2660, 2008
2262008
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma
E Oricchio, G Nanjangud, AL Wolfe, JH Schatz, KJ Mavrakis, M Jiang, ...
Cell 147 (3), 554-564, 2011
1632011
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
HG Wendel, E de Stanchina, E Cepero, S Ray, M Emig, JS Fridman, ...
Proceedings of the National Academy of Sciences 103 (19), 7444-7449, 2006
1432006
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
HG Wendel, E de Stanchina, E Cepero, S Ray, M Emig, JS Fridman, ...
Proceedings of the National Academy of Sciences 103 (19), 7444-7449, 2006
1432006
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ...
Nature medicine 21 (10), 1199, 2015
1402015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
J Van der Meulen, V Sanghvi, K Mavrakis, K Durinck, F Fang, ...
Blood 125 (1), 13-21, 2015
1172015
Tumorigenic activity and therapeutic inhibition of Rheb GTPase
KJ Mavrakis, H Zhu, RLA Silva, JR Mills, J Teruya-Feldstein, SW Lowe, ...
Genes & development 22 (16), 2178-2188, 2008
1172008
Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo
HG Wendel, A Malina, Z Zhao, L Zender, SC Kogan, C Cordon-Cardo, ...
Cancer Research 66 (15), 7639-7646, 2006
1142006
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
JH Schatz, E Oricchio, AL Wolfe, M Jiang, I Linkov, J Maragulia, W Shi, ...
Journal of experimental medicine 208 (9), 1799-1807, 2011
1032011
Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene
X Chen, N Mitsutake, K LaPerle, N Akeno, P Zanzonico, VA Longo, ...
Proceedings of the National Academy of Sciences 106 (19), 7979-7984, 2009
972009
Loss of the HVEM tumor suppressor in lymphoma and restoration by modified CAR-T cells
M Boice, D Salloum, F Mourcin, V Sanghvi, R Amin, E Oricchio, M Jiang, ...
Cell 167 (2), 405-418. e13, 2016
812016
Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
PA Bunn, JD Minna, A Augustyn, AF Gazdar, Y Ouadah, MA Krasnow, ...
Journal of Thoracic Oncology 11 (4), 453-474, 2016
812016
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
E Mets, J Van der Meulen, G Van Peer, M Boice, P Mestdagh, ...
Leukemia 29 (4), 798, 2015
742015
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Articles 1–20