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Yoshitaka Nagai
Yoshitaka Nagai
Department of Neurotherapeutics, Osaka University Graduate School of Medicine
Verified email at neurother.med.osaka-u.ac.jp - Homepage
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13165*2021
A toxic monomeric conformer of the polyglutamine protein
Y Nagai, T Inui, HA Popiel, N Fujikake, K Hasegawa, Y Urade, Y Goto, ...
Nature structural & molecular biology 14 (4), 332-340, 2007
4022007
Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic
T Takahashi, S Kikuchi, S Katada, Y Nagai, M Nishizawa, O Onodera
Human molecular genetics 17 (3), 345-356, 2008
2762008
Harnessing chaperone-mediated autophagy for the selective degradation of mutant huntingtin protein
PO Bauer, A Goswami, HK Wong, M Okuno, M Kurosawa, M Yamada, ...
Nature biotechnology 28 (3), 256-263, 2010
2652010
Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones
N Fujikake, Y Nagai, HA Popiel, Y Okamoto, M Yamaguchi, T Toda
Journal of Biological Chemistry 283 (38), 26188-26197, 2008
2482008
Multiple candidate gene analysis identifies α-synuclein as a susceptibility gene for sporadic Parkinson's disease
I Mizuta, W Satake, Y Nakabayashi, C Ito, S Suzuki, Y Momose, Y Nagai, ...
Human molecular genetics 15 (7), 1151-1158, 2006
2382006
Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening
Y Nagai, T Tucker, H Ren, DJ Kenan, BS Henderson, JD Keene, ...
Journal of Biological Chemistry 275 (14), 10437-10442, 2000
2222000
VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease
E Miura, T Hasegawa, M Konno, M Suzuki, N Sugeno, N Fujikake, ...
Neurobiology of disease 71, 1-13, 2014
1972014
Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level
T Takeuchi, M Suzuki, N Fujikake, HA Popiel, H Kikuchi, S Futaki, K Wada, ...
Proceedings of the National Academy of Sciences 112 (19), E2497-E2506, 2015
1942015
Decrease of the D3 dopamine receptor mRNA expression in lymphocytes from patients with Parkinson's disease
Y Nagai, S Ueno, Y Saeki, F Soga, M Hirano, T Yanagihara
Neurology 46 (3), 791-795, 1996
1931996
Prevention of polyglutamine oligomerization and neurodegeneration by the peptide inhibitor QBP1 in Drosophila
Y Nagai, N Fujikake, K Ohno, H Higashiyama, HA Popiel, J Rahadian, ...
Human molecular genetics 12 (11), 1253-1259, 2003
1702003
Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein
K Araki, N Yagi, K Aoyama, CJ Choong, H Hayakawa, H Fujimura, ...
Proceedings of the National Academy of Sciences 116 (36), 17963-17969, 2019
1342019
Regulatory role of RNA chaperone TDP-43 for RNA misfolding and repeat-associated translation in SCA31
T Ishiguro, N Sato, M Ueyama, N Fujikake, C Sellier, A Kanegami, ...
Neuron 94 (1), 108-124. e7, 2017
1232017
Human peripheral blood lymphocytes express D5 dopamine receptor gene and transcribe the two pseudogenes
N Takahashi, Y Nagai, S Ueno, Y Saeki, T Yanagihara
FEBS letters 314 (1), 23-25, 1992
1151992
Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy
Y Takahashi, Y Okamoto, HA Popiel, N Fujikake, T Toda, M Kinjo, Y Nagai
Journal of Biological Chemistry 282 (33), 24039-24048, 2007
1082007
Expression of the D3 dopamine receptor gene and a novel variant transcript generated by alternative splicing in human peripheral blood lymphocytes
Y Nagai, S Ueno, Y Saeki, F Soga, T Yanagihara
Biochemical and biophysical research communications 194 (1), 368-374, 1993
981993
Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in a Drosophila model of …
M Suzuki, N Fujikake, T Takeuchi, A Kohyama-Koganeya, K Nakajima, ...
Human molecular genetics 24 (23), 6675-6686, 2015
972015
Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches
H Sasayama, M Shimamura, T Tokuda, Y Azuma, T Yoshida, T Mizuno, ...
PLoS One 7 (6), e39483, 2012
932012
Sleep disturbance as a potential modifiable risk factor for Alzheimer’s disease
EN Minakawa, K Wada, Y Nagai
International journal of molecular sciences 20 (4), 803, 2019
912019
Residual laminin-binding activity and enhanced dystroglycan glycosylation by LARGE in novel model mice to dystroglycanopathy
M Kanagawa, A Nishimoto, T Chiyonobu, S Takeda, Y Miyagoe-Suzuki, ...
Human molecular genetics 18 (4), 621-631, 2009
912009
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