| Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination M Vedadi, FH Niesen, A Allali-Hassani, OY Fedorov, PJ Finerty Jr, ... Proceedings of the National Academy of Sciences 103 (43), 15835-15840, 2006 | 722 | 2006 |
| A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-574, 2011 | 547 | 2011 |
| Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity A Schuetz, J Min, A Allali-Hassani, M Schapira, M Shuen, P Loppnau, ... Journal of Biological Chemistry 283 (17), 11355-11363, 2008 | 324 | 2008 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 312 | 2013 |
| Structural biology of human H3K9 methyltransferases H Wu, J Min, VV Lunin, T Antoshenko, L Dombrovski, H Zeng, ... PloS one 5 (1), e8570, 2010 | 308 | 2010 |
| Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin A Schuetz, J Min, T Antoshenko, CL Wang, A Allali-Hassani, A Dong, ... Structure 15 (3), 377-389, 2007 | 300 | 2007 |
| Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation C Bian, C Xu, J Ruan, KK Lee, TL Burke, W Tempel, D Barsyte, J Li, M Wu, ... The EMBO journal 30 (14), 2829-2842, 2011 | 285 | 2011 |
| Structural and chemical profiling of the human cytosolic sulfotransferases A Allali-Hassani, PW Pan, L Dombrovski, R Najmanovich, W Tempel, ... PLoS biology 5 (5), e97, 2007 | 270 | 2007 |
| Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP F Liu, D Barsyte-Lovejoy, F Li, Y Xiong, V Korboukh, XP Huang, ... Journal of medicinal chemistry 56 (21), 8931-8942, 2013 | 263 | 2013 |
| Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ... Journal of medicinal chemistry 52 (24), 7950-7953, 2009 | 246 | 2009 |
| Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein N Nady, A Lemak, JR Walker, GV Avvakumov, MS Kareta, M Achour, ... Journal of Biological Chemistry 286 (27), 24300-24311, 2011 | 235 | 2011 |
| Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium AK Wernimont, JD Artz, P Finerty Jr, YH Lin, M Amani, A Allali-Hassani, ... Nature structural & molecular biology 17 (5), 596-601, 2010 | 233 | 2010 |
| L3MBTL1 recognition of mono-and dimethylated histones J Min, A Allali-Hassani, N Nady, C Qi, H Ouyang, Y Liu, F MacKenzie, ... Nature structural & molecular biology 14 (12), 1229-1230, 2007 | 231 | 2007 |
| Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines. F Liu, X Chen, A Allali-Hassani, AM Quinn, TJ Wigle, GA Wasney, A Dong, ... Journal of medicinal chemistry 53 (15), 5844-5857, 2010 | 218 | 2010 |
| Structural basis for molecular recognition and presentation of histone H3 by WDR5 A Schuetz, A Allali‐Hassani, F Martín, P Loppnau, M Vedadi, A Bochkarev, ... The EMBO journal 25 (18), 4245-4252, 2006 | 214 | 2006 |
| (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells D Barsyte-Lovejoy, F Li, MJ Oudhoff, JH Tatlock, A Dong, H Zeng, H Wu, ... Proceedings of the National Academy of Sciences 111 (35), 12853-12858, 2014 | 182 | 2014 |
| First pass metabolism of ethanol is strikingly influenced by the speed of gastric emptying CM Oneta, UA Simanowski, M Martinez, A Allali-Hassani, X Pares, ... Gut 43 (5), 612-619, 1998 | 169 | 1998 |
| Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 G Senisterra, H Wu, A Allali-Hassani, GA Wasney, D Barsyte-Lovejoy, ... Biochemical Journal 449 (1), 151-159, 2013 | 162 | 2013 |
| Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines F Liu, D Barsyte-Lovejoy, A Allali-Hassani, Y He, JM Herold, X Chen, ... Journal of medicinal chemistry 54 (17), 6139-6150, 2011 | 162 | 2011 |
| Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2 W Zheng, G Ibáñez, H Wu, G Blum, H Zeng, A Dong, F Li, T Hajian, ... Journal of the American Chemical Society 134 (43), 18004-18014, 2012 | 153 | 2012 |
