Brian Ciruna
Brian Ciruna
Hospital for Sick Children, University of Toronto
Verified email at
Cited by
Cited by
Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.
Tropepe, Sibilia, Ciruna, Rossant, Wagner, D van der Kooy
Developmental Biology 208 (1), 1999
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak.
B Ciruna, J Rossant
Developmental Cell 1 (1), 2001
Planar cell polarity signalling couples cell division and morphogenesis during neurulation.
B Ciruna, A Jenny, D Lee, M Mlodzik, AF Schier
Nature 439 (7073), 2006
Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak.
Ciruna, Schwartz, Harpal, Yamaguchi, Rossant
Development 124 (14), 1997
Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia.
Borovina, Superina, Voskas, Ciruna
Nature Cell Biology 12 (4), 2010
Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish.
YA Pan, F T, W TA, S D, W XC, Z S, C B, Sanes JR, L JW, S AF.
Developmental Biology 140 (13), 2013
A fully automated robotic system for microinjection of zebrafish embryos.
Wang, Liu, Gelinas, Ciruna, Sun
PLoS ONE 2 (9), 2007
Production of maternal-zygotic mutant zebrafish by germ-line replacement.
B Ciruna, G Weidinger, H Knaut, B Thisse, C Thisse, E Raz, AF Schier
Proceedings of the National Academy of Sciences 99 (23), 2002
Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature
DT Grimes, CW Boswell, NFC Morante, RM Henkelman, RD Burdine, ...
Science 352 (6291), 1341-1344, 2016
Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein.
Calarco, Superina, O'Hanlon, Gabut, Raj, Pan, Skalska, Clarke, Gelinas, ...
Cell 138 (5), 2009
Expression of the T-box gene Eomesodermin during early mouse development.
B Ciruna, J Rossant
Mechanisms of Development 81, 1999
Variation of BMP3 contributes to dog breed skull diversity.
Schoenebeck, Hutchinson, Byers, Beale, Carrington, Faden, D Rimbault, ...
PLoS Genetics 8 (8), 2012
The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.
TM Saxton, BG Ciruna, D Holmyard, S Kulkarni, K Harpal, J Rossant, ...
Nature Genetics 24 (4), 2000
ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease
Hayes, Gao, Yu, Paria, Henkelman, Wise, Ciruna
Nature Communications 5, 2014
Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development.
Hayes, Naito, Daulat, Angers, Ciruna
Development 140 (8), 2013
Oriented cell motility and division underlie early limb bud morphogenesis.
Wyngaarden, Vogeli, Ciruna, Wells, Hadjantonakis, H S.
Development 137 (15), 2010
Anisotropic stress orients remodelling of mammalian limb bud ectoderm
K Lau, H Tao, H Liu, J Wen, K Sturgeon, N Sorfazlian, S Lazic, J Burrows, ...
Nature Cell Biology, 2015
Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.
Persaud, Alberts, Hayes, Guettler, Clarke, Sicheri, Dirks, Ciruna, Rotin
EMBO J 30 (16), 2011
Understanding idiopathic scoliosis: a new zebrafish school of thought
CW Boswell, B Ciruna
Trends in Genetics 33 (3), 183-196, 2017
Convergence and extension movements during vertebrate gastrulation.
Yin, Ciruna, Solnica-Krezel
Current Topics in Developmental Biology 89, 2009
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