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Kyle L Flannigan
Kyle L Flannigan
Verified email at ucalgary.ca
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Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production
JP Motta, KL Flannigan, TA Agbor, JK Beatty, RW Blackler, ...
Inflammatory bowel diseases 21 (5), 1006-1017, 2015
1532015
Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics
JL Wallace, RW Blackler, MV Chan, GJ Da Silva, W Elsheikh, ...
Antioxidants & redox signaling 22 (5), 398-410, 2015
1342015
Cutting edge: IL-36 receptor promotes resolution of intestinal damage
O Medina-Contreras, A Harusato, H Nishio, KL Flannigan, V Ngo, G Leoni, ...
The journal of immunology 196 (1), 34-38, 2016
1222016
Gaseous mediators in resolution of inflammation
JL Wallace, A Ianaro, KL Flannigan, G Cirino
Seminars in immunology 27 (3), 227-233, 2015
1012015
IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria
KL Flannigan, VL Ngo, D Geem, A Harusato, SA Hirota, CA Parkos, ...
Mucosal immunology 10 (3), 673-684, 2017
982017
Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis
KL Flannigan, TA Agbor, RW Blackler, JJ Kim, WI Khan, EF Verdu, ...
Proceedings of the National Academy of Sciences 111 (37), 13559-13564, 2014
842014
Enhanced synthesis and diminished degradation of hydrogen sulfide in experimental colitis: a site-specific, pro-resolution mechanism
KL Flannigan, JGP Ferraz, R Wang, JL Wallace
PLoS One 8 (8), e71962, 2013
722013
Eukaryotic and prokaryotic contributions to colonic hydrogen sulfide synthesis
KL Flannigan, KD McCoy, JL Wallace
American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (1 …, 2011
682011
Deciphering the pathogenesis of NSAID enteropathy using proton pump inhibitors and a hydrogen sulfide-releasing NSAID
RW Blackler, G De Palma, A Manko, GJ Da Silva, KL Flannigan, P Bercik, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 308 (12 …, 2015
652015
Vancomycin relieves mycophenolate mofetil–induced gastrointestinal toxicity by eliminating gut bacterial β-glucuronidase activity
MR Taylor, KL Flannigan, H Rahim, A Mohamud, IA Lewis, SA Hirota, ...
Science advances 5 (8), eaax2358, 2019
602019
Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer
W Elsheikh, RW Blackler, KL Flannigan, JL Wallace
Nitric Oxide 41, 131-137, 2014
572014
Intestinal antigen-presenting cells: key regulators of immune homeostasis and inflammation
KL Flannigan, D Geem, A Harusato, TL Denning
The American journal of pathology 185 (7), 1809-1819, 2015
562015
Segmented filamentous bacteria‐induced immune responses: a balancing act between host protection and autoimmunity
KL Flannigan, TL Denning
Immunology 154 (4), 537-546, 2018
542018
Proresolution effects of hydrogen sulfide during colitis are mediated through hypoxia‐inducible factor‐1α
KL Flannigan, TA Agbor, JP Motta, JGP Ferraz, R Wang, AG Buret, ...
The FASEB Journal 29 (4), 1591-1602, 2015
502015
An intact microbiota is required for the gastrointestinal toxicity of the immunosuppressant mycophenolate mofetil
KL Flannigan, MR Taylor, SK Pereira, J Rodriguez-Arguello, AW Moffat, ...
The Journal of Heart and Lung Transplantation 37 (9), 1047-1059, 2018
492018
Harnessing regulatory T cells for the treatment of inflammatory bowel disease
D Geem, A Harusato, K Flannigan, TL Denning
Inflammatory bowel diseases 21 (6), 1409-1418, 2015
432015
Targeting the pregnane X receptor using microbial metabolite mimicry
Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ...
EMBO molecular medicine 12 (4), e11621, 2020
362020
Constitutive androstane receptor regulates the intestinal mucosal response to injury
GM Hudson, KL Flannigan, SL Erickson, FA Vicentini, A Zamponi, ...
British journal of pharmacology 174 (12), 1857-1871, 2017
352017
Xenobiotic receptor-mediated regulation of intestinal barrier function and innate immunity
HS Ranhotra, KL Flannigan, M Brave, S Mukherjee, DJ Lukin, SA Hirota, ...
Nuclear receptor research 3, 2016
322016
Changes in Composition of the Gut Bacterial Microbiome after Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in a Pediatric Heart …
KL Flannigan, T Rajbar, A Moffat, LS McKenzie, F Dicke, K Rioux, ...
Frontiers in Cardiovascular Medicine 4, 17, 2017
272017
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