Valentina Gandin
Valentina Gandin
Janelia Research Campus
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mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation
M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ...
Cell metabolism 18 (5), 698-711, 2013
Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation
V Gandin, A Miluzio, AM Barbieri, A Beugnet, H Kiyokawa, PC Marchisio, ...
Nature 455 (7213), 684-688, 2008
S6K1 plays a critical role in early adipocyte differentiation
LS Carnevalli, K Masuda, F Frigerio, O Le Bacquer, SH Um, V Gandin, ...
Developmental cell 18 (5), 763-774, 2010
nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs
V Gandin, L Masvidal, L Hulea, SP Gravel, M Cargnello, S McLaughlan, ...
Genome research 26 (5), 636-648, 2016
Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale
V Gandin, K Sikström, T Alain, M Morita, S McLaughlan, O Larsson, ...
JoVE (Journal of Visualized Experiments), e51455, 2014
Intracellular mRNA transport and localized translation
S Das, M Vera, V Gandin, RH Singer, E Tutucci
Nature reviews Molecular cell biology 22 (7), 483-504, 2021
eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies
T Alain, M Morita, BD Fonseca, A Yanagiya, N Siddiqui, M Bhat, D Zammit, ...
Cancer research 72 (24), 6468-6476, 2012
DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation
N Liberman, V Gandin, YV Svitkin, M David, G Virgili, M Jaramillo, ...
Nucleic acids research 43 (7), 3764-3775, 2015
Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner
R Miloslavski, E Cohen, A Avraham, Y Iluz, Z Hayouka, J Kasir, ...
Journal of molecular cell biology 6 (3), 255-266, 2014
mTORC1 and CK2 coordinate ternary and eIF4F complex assembly
V Gandin, L Masvidal, M Cargnello, L Gyenis, S McLaughlan, Y Cai, ...
Nature communications 7 (1), 11127, 2016
Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes
P Thandapani, J Song, V Gandin, Y Cai, SG Rouleau, JM Garant, ...
Elife 4, e06234, 2015
Distinct Translational Control in CD4+ T Cell Subsets
E Bjur, O Larsson, E Yurchenko, L Zheng, V Gandin, I Topisirovic, S Li, ...
PLoS genetics 9 (5), e1003494, 2013
RACK1 function in cell motility and protein synthesis
V Gandin, D Senft, I Topisirovic, ZA Ronai
Genes & cancer 4 (9-10), 369-377, 2013
Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex
V Gandin, GJ Gutierrez, LM Brill, T Varsano, Y Feng, P Aza-Blanc, Q Au, ...
Molecular and cellular biology, 2013
Fibronectin controls cap-dependent translation through β1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways
C Gorrini, F Loreni, V Gandin, LA Sala, N Sonenberg, PC Marchisio, ...
Proceedings of the National Academy of Sciences 102 (26), 9200-9205, 2005
Largen: a molecular regulator of mammalian cell size control
K Yamamoto, V Gandin, M Sasaki, S McCracken, W Li, JL Silvester, ...
Molecular cell 53 (6), 904-915, 2014
FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation
D Cook, E Nuro, EV Jones, HF Altimimi, WT Farmer, V Gandin, E Hanna, ...
Cell reports 9 (4), 1402-1416, 2014
Inactive C-terminal telomerase reverse transcriptase insertion splicing variants are dominant-negative inhibitors of telomerase
S Zhu, P Rousseau, C Lauzon, V Gandin, I Topisirovic, C Autexier
Biochimie 101, 93-103, 2014
The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner
YK Im, R La Selva, V Gandin, JR Ha, V Sabourin, N Sonenberg, ...
Oncogene 34 (13), 1729-1735, 2015
The mTORC1/S6K/PDCD4/eIF4A axis determines outcome of mitotic arrest
M Moustafa-Kamal, TJ Kucharski, W El-Assaad, YM Abbas, V Gandin, ...
Cell Reports 33 (1), 2020
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