| High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 852 | 2015 |
| Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 165 | 2017 |
| Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus in plant defense and viral counter-defense T Blevins, R Rajeswaran, M Aregger, BK Borah, M Schepetilnikov, ... Nucleic acids research 39 (12), 5003-5014, 2011 | 138 | 2011 |
| CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. M Zimmermann, O Murina, MAM Reijns, A Agathanggelou, R Challis, ... Nature, 2018 | 125 | 2018 |
| Primary and secondary siRNAs in geminivirus-induced gene silencing M Aregger, BK Borah, J Seguin, R Rajeswaran, EG Gubaeva, AS Zvereva, ... PLoS pathogens 8 (9), e1002941, 2012 | 122 | 2012 |
| Sequencing of RDR6-dependent double-stranded RNAs reveals novel features of plant siRNA biogenesis R Rajeswaran, M Aregger, AS Zvereva, BK Borah, EG Gubaeva, ... Nucleic acids research 40 (13), 6241-6254, 2012 | 56 | 2012 |
| Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons T Gonatopoulos-Pournatzis, M Wu, U Braunschweig, J Roth, H Han, ... Molecular Cell 72 (3), 510-524. e12, 2018 | 35 | 2018 |
| CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription M Aregger, A Kaskar, D Varshney, ME Fernandez-Sanchez, ... Molecular Cell 61 (5), 734-746, 2016 | 26 | 2016 |
| Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites M Aregger, VH Cowling Biochemical Journal 455 (1), 67-73, 2013 | 23 | 2013 |
| Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform T Gonatopoulos-Pournatzis, M Aregger, KR Brown, S Farhangmehr, ... Nature Biotechnology, 2020 | 15 | 2020 |
| E2F1-dependent methyl cap formation requires RNA pol II phosphorylation M Aregger, VH Cowling Cell Cycle 11 (11), 2146-2148, 2012 | 14 | 2012 |
| Regulation of mRNA capping in the cell cycle M Aregger, VH Cowling RNA biology 14 (1), 11-14, 2017 | 13 | 2017 |
| Pooled Lentiviral CRISPR-Cas9 Screens for Functional Genomics in Mammalian Cells M Aregger, M Chandrashekhar, AHY Tong, K Chan, J Moffat Brain Tumor Stem Cells, 169-188, 2019 | 11 | 2019 |
| Functional genomic landscape of cancer-intrinsic evasion of killing by T cells KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ... Nature 586 (7827), 120-126, 2020 | 8 | 2020 |
| Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism M Aregger, KA Lawson, M Billmann, M Costanzo, AHY Tong, K Chan, ... Nature Metabolism, 1-15, 2020 | 5 | 2020 |
| Systematic discovery and classification of human cell line essential genes T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, S Angers, ... bioRxiv, 015412, 2015 | 4 | 2015 |
| Extensive mapping of an innate immune network with CRISPR M Aregger, T Hart, J Moffat Molecular systems biology 11 (7), 821, 2015 | 1 | 2015 |
| Major functional bias for mitochondrial complexes in genome-wide CRISPR screens M Rahman, M Billmann, M Costanzo, M Aregger, AHY Tong, K Chan, ... bioRxiv, 2020 | | 2020 |
| Systematic mapping of genetic interactions for de novo fatty acid synthesis M Aregger, KA Lawson, M Billmann, M Costanzo, AHY Tong, K Chan, ... bioRxiv, 834721, 2019 | | 2019 |
| Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT) M Aregger University of Dundee, 2013 | | 2013 |
Jason MoffatProfessor, University of TorontoVerified email at utoronto.ca
