| Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth L Lv, D Li, D Zhao, R Lin, Y Chu, H Zhang, Z Zha, Y Liu, Z Li, Y Xu, ... Molecular cell 42 (6), 719-730, 2011 | 615 | 2011 |
| Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth R Lin, R Tao, X Gao, T Li, X Zhou, KL Guan, Y Xiong, QY Lei Molecular cell 51 (4), 506-518, 2013 | 347 | 2013 |
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling R Lin, S Elf, C Shan, HB Kang, Q Ji, L Zhou, T Hitosugi, L Zhang, S Zhang, ... Nature cell biology 17 (11), 1484, 2015 | 260 | 2015 |
| Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation J Wang, C Luo, C Shan, Q You, J Lu, S Elf, Y Zhou, Y Wen, JL Vinkenborg, ... Nature chemistry 7 (12), 968-979, 2015 | 221 | 2015 |
| Prevention of dietary-fat-fueled ketogenesis attenuates BRAF V600E tumor growth S Xia, R Lin, L Jin, L Zhao, HB Kang, Y Pan, S Liu, G Qian, Z Qian, ... Cell metabolism 25 (2), 358-373, 2017 | 154 | 2017 |
| Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling HB Kang, J Fan, R Lin, S Elf, Q Ji, L Zhao, L Jin, JH Seo, C Shan, ... Molecular cell 59 (3), 345-358, 2015 | 141 | 2015 |
| Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth C Shan, S Elf, Q Ji, HB Kang, L Zhou, T Hitosugi, L Jin, R Lin, L Zhang, ... Molecular cell 55 (4), 552-565, 2014 | 137 | 2014 |
| MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ... Cancer cell 34 (2), 315-330. e7, 2018 | 108 | 2018 |
| Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth J Fan, R Lin, S Xia, D Chen, SE Elf, S Liu, Y Pan, H Xu, Z Qian, M Wang, ... Molecular cell 64 (5), 859-874, 2016 | 86 | 2016 |
| Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect J Fan, HB Kang, C Shan, S Elf, R Lin, J Xie, TL Gu, M Aguiar, S Lonning, ... Journal of Biological Chemistry 289 (38), 26533-26541, 2014 | 86 | 2014 |
| Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin S Elf, R Lin, S Xia, Y Pan, C Shan, S Wu, S Lonial, M Gaddh, ML Arellano, ... Oncogene 36 (2), 254, 2017 | 54 | 2017 |
| γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A X Gao, L Zhao, S Liu, Y Li, S Xia, D Chen, M Wang, S Wu, Q Dai, H Vu, ... Molecular cell, 2019 | 41 | 2019 |
| Acetylation control of cancer cell metabolism R Lin, X Zhou, W Huang, D Zhao, L Lv, Y Xiong, KL Guan, QY Lei Current pharmaceutical design 20 (15), 2627-2633, 2014 | 38 | 2014 |
| HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers L Zhao, J Fan, S Xia, Y Pan, S Liu, G Qian, Z Qian, HB Kang, JL Arbiser, ... Journal of Biological Chemistry, jbc. M117. 788778, 2017 | 33 | 2017 |
| Mutant and wild-type isocitrate dehydrogenase 1 share enhancing mechanisms involving distinct tyrosine kinase cascades in cancer D Chen, S Xia, M Wang, R Lin, Y Li, H Mao, M Aguiar, CA Famulare, ... Cancer discovery 9 (6), 756-777, 2019 | 25 | 2019 |
| The dietary supplement chondroitin-4-sulfate exhibits oncogene-specific pro-tumor effects on BRAF V600E melanoma cells R Lin, S Xia, C Shan, D Chen, Y Liu, X Gao, M Wang, HB Kang, Y Pan, ... Molecular cell 69 (6), 923-937. e8, 2018 | 21 | 2018 |
