Harkness, T
Harkness, T
Professor, Biochemistry, Microbiology, and Immunology, University of Saskatchewan
Verified email at usask.ca - Homepage
TitleCited byYear
Elevated histone expression promotes life span extension
J Feser, D Truong, C Das, JJ Carson, J Kieft, T Harkness, JK Tyler
Molecular cell 39 (5), 724-735, 2010
2732010
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene …
X Ling, TA Harkness, MC Schultz, G Fisher-Adams, M Grunstein
Genes & Development 10 (6), 686-699, 1996
1491996
A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria
TA Harkness, FE Nargang, I Van Der Klei, W Neupert, R Lill
The Journal of Cell Biology 124 (5), 637-648, 1994
1171994
Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro …
MG Surette, T Harkness, G Chaconas
Journal of Biological Chemistry 266 (5), 3118-3124, 1991
781991
Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells
AA Goldberg, A Beach, GF Davies, TAA Harkness, A LeBlanc, ...
Oncotarget 2 (10), 761, 2011
512011
The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex
SDL Postnikoff, ME Malo, B Wong, TAA Harkness
PLoS genetics 8 (3), e1002583, 2012
492012
A functional analysis reveals dependence on the anaphase-promoting complex for prolonged life span in yeast
TAA Harkness, KA Shea, C Legrand, M Brahmania, GF Davies
Genetics 168 (2), 759-774, 2004
482004
Chromatin assembly in a yeast whole-cell extract
MC Schultz, DJ Hockman, TAA Harkness, WI Garinther, BA Altheim
Proceedings of the National Academy of Sciences 94 (17), 9034-9039, 1997
471997
Inactivation of the Neurospora crassa gene encoding the mitochondrial protein import receptor MOM19 by the technique of" sheltered RIP".
TA Harkness, RL MetZenberg, H Schneider, R Lill, W Neupert, ...
Genetics 136 (1), 107-118, 1994
451994
The ubiquitin-dependent targeting pathway in Saccharomyces cerevisiae plays a critical role in multiple chromatin assembly regulatory steps
TAA Harkness, GF Davies, V Ramaswamy, TG Arnason
Genetics 162 (2), 615-632, 2002
352002
Troglitazone reverses the multiple drug resistance phenotype in cancer cells
GF Davies, BHJ Juurlink, TAA Harkness
Drug design, development and therapy 3, 79, 2009
332009
Disruption of the nuclear gene encoding the 20.8-kDa subunit of NADH: ubiquinone reductase ofNeurospora mitochondria
MV da Silva, PC Alves, M Duarte, N Mota, A Lobo-da-Cunha, A Videira, ...
Molecular and General Genetics MGG 252 (1-2), 177-183, 1996
331996
Troglitazone inhibits histone deacetylase activity in breast cancer cells
GF Davies, AR Ross, TG Arnason, BHJ Juurlink, TAA Harkness
Cancer letters 288 (2), 236-250, 2010
272010
Troglitazone overcomes doxorubicin-resistance in resistant K562 leukemia cells
GF Davies, WJ Roesler, BHJ Juurlink, TAA Harkness
Leukemia & lymphoma 46 (8), 1199-1206, 2005
262005
Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae
TG Arnason, MG Pisclevich, MD Dash, GF Davies, TAA Harkness
Eukaryotic cell 4 (1), 134-146, 2005
242005
Disruption of the gene encoding the 78-kilodalton subunit of the peripheral arm of complex I in Neurospora crassa by repeat induced point mutation (RIP)
TAA Harkness, RA Rothery, JH Weiner, S Werner, JE Azevedo, A Videira, ...
Current genetics 27 (4), 339-350, 1995
211995
Development, maintenance, and reversal of multiple drug resistance: at the crossroads of TFPI1, ABC transporters, and HIF1
T Arnason, T Harkness
Cancers 7 (4), 2063-2082, 2015
202015
Contribution of CAF-I to anaphase-promoting-complex-mediated mitotic chromatin assembly in Saccharomyces cerevisiae
TAA Harkness, TG Arnason, C Legrand, MG Pisclevich, GF Davies, ...
Eukaryotic cell 4 (4), 673-684, 2005
192005
A genome scale screen for mutants with delayed exit from mitosis: Ire1-independent induction of autophagy integrates ER homeostasis into mitotic lifespan
A Ghavidel, K Baxi, V Ignatchenko, M Prusinkiewicz, TG Arnason, ...
PLoS genetics 11 (8), e1005429, 2015
172015
Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer
G Davies, L Lobanova, W Dawicki, G Groot, JR Gordon, M Bowen, ...
PLoS One 12 (12), e0187191, 2017
162017
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