Harkness, T
Harkness, T
Professor, Biochemistry, Microbiology, and Immunology, University of Saskatchewan
Verified email at usask.ca - Homepage
Cited by
Cited by
Elevated histone expression promotes life span extension
J Feser, D Truong, C Das, JJ Carson, J Kieft, T Harkness, JK Tyler
Molecular cell 39 (5), 724-735, 2010
Yeast histone H3 and H4 amino termini are important for nucleosome assembly in vivo and in vitro: redundant and position-independent functions in assembly but not in gene …
X Ling, TA Harkness, MC Schultz, G Fisher-Adams, M Grunstein
Genes & development 10 (6), 686-699, 1996
A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria
TA Harkness, FE Nargang, I Van Der Klei, W Neupert, R Lill
Journal of Cell Biology 124 (5), 637-648, 1994
Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro …
MG Surette, T Harkness, G Chaconas
Journal of Biological Chemistry 266 (5), 3118-3124, 1991
Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells
AA Goldberg, A Beach, GF Davies, TAA Harkness, A LeBlanc, ...
Oncotarget 2 (10), 761, 2011
The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex
SDL Postnikoff, ME Malo, B Wong, TAA Harkness
PLoS genetics 8 (3), e1002583, 2012
Chromatin assembly in a yeast whole-cell extract
MC Schultz, DJ Hockman, TAA Harkness, WI Garinther, BA Altheim
Proceedings of the National Academy of Sciences 94 (17), 9034-9039, 1997
A functional analysis reveals dependence on the anaphase-promoting complex for prolonged life span in yeast
TAA Harkness, KA Shea, C Legrand, M Brahmania, GF Davies
Genetics 168 (2), 759-774, 2004
Inactivation of the Neurospora crassa gene encoding the mitochondrial protein import receptor MOM19 by the technique of" sheltered RIP".
TA Harkness, RL MetZenberg, H Schneider, R Lill, W Neupert, ...
Genetics 136 (1), 107-118, 1994
Troglitazone reverses the multiple drug resistance phenotype in cancer cells
GF Davies, BHJ Juurlink, TAA Harkness
Drug design, development and therapy 3, 79, 2009
The Ubiquitin-Dependent Targeting Pathway in Saccharomyces cerevisiae Plays a Critical Role in Multiple Chromatin Assembly Regulatory Steps
TAA Harkness, GF Davies, V Ramaswamy, TG Arnason
Genetics 162 (2), 615-632, 2002
Development, maintenance, and reversal of multiple drug resistance: at the crossroads of TFPI1, ABC transporters, and HIF1
T Arnason, T Harkness
Cancers 7 (4), 2063-2082, 2015
Metformin inhibits the development, and promotes the resensitization, of treatment-resistant breast cancer
G Davies, L Lobanova, W Dawicki, G Groot, JR Gordon, M Bowen, ...
PLoS One 12 (12), e0187191, 2017
Troglitazone overcomes doxorubicin-resistance in resistant K562 leukemia cells
GF Davies, WJ Roesler, BHJ Juurlink, TAA Harkness
Leukemia & lymphoma 46 (8), 1199-1206, 2005
Disruption of the nuclear gene encoding the 20.8-kDa subunit of NADH: ubiquinone reductase of Neurospora mitochondria
MV da Silva, PC Alves, M Duarte, N Mota, A Lobo-da-Cunha, A Videira, ...
Molecular and General Genetics MGG 252 (1), 177-183, 1996
Troglitazone inhibits histone deacetylase activity in breast cancer cells
GF Davies, AR Ross, TG Arnason, BHJ Juurlink, TAA Harkness
Cancer letters 288 (2), 236-250, 2010
Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan
Z Hu, B Xia, SDL Postnikoff, ZJ Shen, AS Tomoiaga, TA Harkness, ...
Elife 7, e35551, 2018
Disruption of the gene encoding the 78-kilodalton subunit of the peripheral arm of complex I in Neurospora crassa by repeat induced point mutation (RIP)
TAA Harkness, RA Rothery, JH Weiner, S Werner, JE Azevedo, A Videira, ...
Current genetics 27 (4), 339-350, 1995
Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans
K Baxi, A Ghavidel, B Waddell, TA Harkness, CE de Carvalho
Genetics 207 (1), 83-101, 2017
A genome scale screen for mutants with delayed exit from mitosis: Ire1-independent induction of autophagy integrates ER homeostasis into mitotic lifespan
A Ghavidel, K Baxi, V Ignatchenko, M Prusinkiewicz, TG Arnason, ...
PLoS genetics 11 (8), e1005429, 2015
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