Gareth Lim
Gareth Lim
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Hyperinsulinemia drives diet-induced obesity independently of brain insulin production
AE Mehran, NM Templeman, GS Brigidi, GE Lim, KY Chu, X Hu, ...
Cell metabolism 16 (6), 723-737, 2012
Glucagon-like peptide 1 secretion by the L-cell: the view from within
GE Lim, PL Brubaker
Diabetes 55 (Supplement_2), S70-S77, 2006
Prenatal exposure to nicotine causes postnatal obesity and altered perivascular adipose tissue function
YJ Gao, AC Holloway, ZH Zeng, GE Lim, JJ Petrik, WG Foster, RMKW Lee
Obesity research 13 (4), 687-692, 2005
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell
GE Lim, GJ Huang, N Flora, D LeRoith, CJ Rhodes, PL Brubaker
Endocrinology 150 (2), 580-591, 2009
Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells
F Yi, J Sun, GE Lim, IG Fantus, PL Brubaker, T Jin
Endocrinology 149 (5), 2341-2351, 2008
A causal role for hyperinsulinemia in obesity
NM Templeman, S Skovsø, MM Page, GE Lim, JD Johnson
Journal of Endocrinology 232 (3), R173-R183, 2017
Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 …
AC Holloway, GE Lim, JJ Petrik, WG Foster, KM Morrison, HC Gerstein
Diabetologia 48, 2661-2666, 2005
Reduced circulating insulin enhances insulin sensitivity in old mice and extends lifespan
NM Templeman, S Flibotte, JHL Chik, S Sinha, GE Lim, LJ Foster, ...
Cell reports 20 (2), 451-463, 2017
14-3-3ζ coordinates adipogenesis of visceral fat
GE Lim, T Albrecht, M Piske, K Sarai, JTC Lee, HS Ramshaw, S Sinha, ...
Nature communications 6 (1), 7671, 2015
Synergistic effects between FSH and 1, 1‐dichloro‐2, 2‐bis (P‐chlorophenyl) ethylene (P, P′‐DDE) on human granulosa cell aromatase activity
EV Younglai, AC Holloway, GE Lim, WG Foster
Human Reproduction 19 (5), 1089-1093, 2004
Musashi expression in β-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes
M Szabat, TB Kalynyak, GE Lim, KY Chu, YH Yang, A Asadi, BK Gage, ...
Cell death & disease 2 (11), e232-e232, 2011
The rho guanosine 5′-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine …
GE Lim, M Xu, J Sun, T Jin, PL Brubaker
Endocrinology 150 (12), 5249-5261, 2009
Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells
T Boothe, GE Lim, H Cen, S Skovsø, M Piske, SN Li, IR Nabi, P Gilon, ...
Molecular metabolism 5 (5), 366-378, 2016
Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain
MM Page, S Skovsø, H Cen, AP Chiu, DA Dionne, DF Hutchinson, GE Lim, ...
The FASEB Journal 32 (3), 1196, 2018
14-3-3 proteins are essential signalling hubs for beta cell survival
GE Lim, M Piske, JD Johnson
Diabetologia 56, 825-837, 2013
Effects of insulin on human pancreatic cancer progression modeled in vitro
MT Chan, GE Lim, S Skovsø, YHC Yang, T Albrecht, EU Alejandro, ...
BMC cancer 14, 1-12, 2014
Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription
EU Alejandro, GE Lim, AE Mehran, X Hu, F Taghizadeh, D Pelipeychenko, ...
The FASEB Journal 25 (11), 3884, 2011
Ywhaz/14-3-3ζ deletion improves glucose tolerance through a GLP-1-dependent mechanism
GE Lim, M Piske, JE Lulo, HS Ramshaw, AF Lopez, JD Johnson
Endocrinology 157 (7), 2649-2659, 2016
Is dynamic autocrine insulin signaling possible? A mathematical model predicts picomolar concentrations of extracellular monomeric insulin within human pancreatic islets
M Wang, J Li, GE Lim, JD Johnson
PLoS One 8 (6), e64860, 2013
Can 14-3-3 proteins serve as therapeutic targets for the treatment of metabolic diseases?
K Diallo, AK Oppong, GE Lim
Pharmacological research 139, 199-206, 2019
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